Hh/Gli antagonist in acute myeloid leukemia with CBFA2T3-GLIS2 fusion gene

Recurrent abnormalities can be used for risk group stratification in pediatric AMKL: a retrospective intergroup study

(2016) Jasmijn D. E. de Rooij et al.   BLOOD

Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects

(2015) J. Wellbrock et al.   CLINICAL CANCER RESEARCH

Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding

(2015) Akwasi Agyeman et al.   Oncotarget

CBFA2T3-GLIS2 fusion transcript is a novel common feature in pediatric, cytogenetically normal AML, not restricted to FAB M7 subtype

(2013) R. Masetti et al.   BLOOD

An Inv(16)(p13.3q24.3)-Encoded CBFA2T3-GLIS2 Fusion Protein Defines an Aggressive Subtype of Pediatric Acute Megakaryoblastic Leukemia

(2012) Tanja A. Gruber et al.   CANCER CELL

Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models

(2012) Clarisse Thiollier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Gli inhibitor GANT61 causes apoptosis in myeloid leukemia cells and acts in synergy with rapamycin

(2012) Deng Pan et al.   LEUKEMIA RESEARCH