XIAP BIR domain suppresses miR-200a expression and subsequently promotes EGFR protein translation and anchorage-independent growth of bladder cancer cell

Cancer statistics, 2016

(2016) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Epidermal growth factor receptor is expressed and active in a subset of acute myeloid leukemia

(2016) Hasan Mahmud et al.   Journal of Hematology & Oncology

The X-linked inhibitor of apoptosis protein is an independent prognostic marker for rectal adenocarcinoma after preoperative chemoradiotherapy

(2016) Yi-Ting Chen et al.   VIRCHOWS ARCHIV

X-linked inhibitor of apoptosis protein mediates tumor cell resistance to antibody-dependent cellular cytotoxicity

(2016) M K Evans et al.   Cell Death & Disease

Biomarkers and targeted systemic therapies in advanced non-small cell lung cancer

(2015) Mukesh Kumar et al.   MOLECULAR ASPECTS OF MEDICINE

High levels of X-linked Inhibitor-of-Apoptosis Protein (XIAP) are indicative of radio chemotherapy resistance in rectal cancer

(2015) L. Flanagan et al.   Radiation Oncology

Predicting effective microRNA target sites in mammalian mRNAs

(2015) Vikram Agarwal et al.   eLife

X-linked inhibitor of apoptosis protein (XIAP) lacking RING domain localizes to the nuclear and promotes cancer cell anchorage-independent growth by targeting the E2F1/Cyclin E axis

(2015) Zipeng Cao et al.   Oncotarget

Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention

(2015) Nicole M. Davis et al.   Oncotarget

Crucial Role of c-Jun Phosphorylation at Ser63/73 Mediated by PHLPP Protein Degradation in the Cheliensisin A Inhibition of Cell Transformation

(2014) J. Zhu et al.   Cancer Prevention Research

Production, purification and titration of a lentivirus-based vector for gene delivery purposes

(2014) Masoud Nasri et al.   CYTOTECHNOLOGY

EGFR as a potential therapeutic target for a subset of muscle-invasive bladder cancers presenting a basal-like phenotype

(2014) S. Rebouissou et al.   Science Translational Medicine

Evaluation of urinary XIAP as a diagnostic biomarker of carcinoma of urinary bladder

(2014) A. K. Srivastava et al.   TUMOR BIOLOGY

A novel antagonist to the inhibitors of apoptosis (IAPs) potentiates cell death in EGFR-overexpressing non-small-cell lung cancer cells

(2014) S-H Lee et al.   Cell Death & Disease

X-linked Inhibitor of Apoptosis Protein (XIAP) Regulation of Cyclin D1 Protein Expression and Cancer Cell Anchorage-independent Growth via Its E3 Ligase-mediated Protein Phosphatase 2A/c-Jun Axis

(2013) Zipeng Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genomic amplification and high expression of EGFR are key targetable oncogenic events in malignant peripheral nerve sheath tumor

(2013) Xiaoling Du et al.   Journal of Hematology & Oncology

microRNA, Cancer and Cancer Chemoprevention

(2013) Xun Che et al.   Current Molecular Pharmacology

XIAP as a Radioresistance Factor and Prognostic Marker for Radiotherapy in Human Rectal Adenocarcinoma

(2012) Driffa Moussata et al.   AMERICAN JOURNAL OF PATHOLOGY

Role of epidermal growth factor receptor in breast cancer

(2012) Hiroko Masuda et al.   BREAST CANCER RESEARCH AND TREATMENT

Targeting the EGFR signaling pathway in cancer therapy

(2012) Parthasarathy Seshacharyulu et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

RhoGDI SUMOylation at Lys-138 Increases Its Binding Activity to Rho GTPase and Its Inhibiting Cancer Cell Motility

(2012) Jianxiu Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting IAP proteins for therapeutic intervention in cancer

(2012) Simone Fulda et al.   NATURE REVIEWS DRUG DISCOVERY

E3 Ligase Activity of XIAP RING Domain Is Required for XIAP-Mediated Cancer Cell Migration, but Not for Its RhoGDI Binding Activity

(2012) Jinyi Liu et al.   PLoS One

CD95 death receptor and epidermal growth factor receptor (EGFR) in liver cell apoptosis and regeneration

(2011) Roland Reinehr et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation

(2011) Tripat Kaur Oberoi et al.   EMBO JOURNAL

X-linked Inhibitor of Apoptosis Protein (XIAP) Mediates Cancer Cell Motility via Rho GDP Dissociation Inhibitor (RhoGDI)-dependent Regulation of the Cytoskeleton

(2011) Jinyi Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential roles of ERK and Akt pathways in regulation of EGFR-mediated signaling and motility in prostate cancer cells

(2010) Y Gan et al.   ONCOGENE

XIAP expression is post-transcriptionally upregulated in childhood ALL and is associated with glucocorticoid response in T-cell ALL

(2010) Patrick Hundsdoerfer et al.   PEDIATRIC BLOOD & CANCER

miR-200 Expression Regulates Epithelial-to-Mesenchymal Transition in Bladder Cancer Cells and Reverses Resistance to Epidermal Growth Factor Receptor Therapy

(2009) L. Adam et al.   CLINICAL CANCER RESEARCH

Bladder cancer

(2009) Donald S Kaufman et al.   LANCET

microRNA-7 Inhibits the Epidermal Growth Factor Receptor and the Akt Pathway and Is Down-regulated in Glioblastoma

(2008) B. Kefas et al.   CANCER RESEARCH

Rho GTPases in cancer cell biology

(2008) Francisco M. Vega et al.   FEBS LETTERS

Anti-cancer Effects of JKA97 Are Associated with Its Induction of Cell Apoptosis via a Bax-dependent and p53-independent Pathway

(2008) Wenjing Luo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival

(2007) Melissa R. Junttila et al.   FASEB JOURNAL