Journal
DEVELOPMENT GROWTH & DIFFERENTIATION
Volume 57, Issue 4, Pages 324-332Publisher
WILEY
DOI: 10.1111/dgd.12211
Keywords
embryogenesis; epigenesis; germline segregation; multipotent cells; preformation
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Funding
- JSPS KAKENHI [23570252]
- Grants-in-Aid for Scientific Research [23570252] Funding Source: KAKEN
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Germline segregation is a complex process by which germline cells are separated from somatic tissues during development. Recent animal studies on germline segregation allow for comparisons of the mechanisms used by different species and to propose evolutionary scenarios underlying the diversification of these processes. In this review, several proposed models of germline segregation are presented, and in addition, recent findings from the increasing number of studies are discussed, particularly concerning the need to reconsider these models based on available data.
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