Reflux esophagitis and its role in the pathogenesis of Barrett’s metaplasia

Hypoxia-inducible factor-2α plays a role in mediating oesophagitis in GORD

(2016) Xiaofang Huo et al.   GUT

Association of Acute Gastroesophageal Reflux Disease With Esophageal Histologic Changes

(2016) Kerry B. Dunbar et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2015

(2016) Katsuhiko Iwakiri et al.   JOURNAL OF GASTROENTEROLOGY

In oesophageal squamous cells, nitric oxide causes S-nitrosylation of Akt and blocks SOX2 (sex determining region Y-box 2) expression

(2015) Kiyotaka Asanuma et al.   GUT

Bile acids induce Delta-like 1 expression via Cdx2-dependent pathway in the development of Barrett’s esophagus

(2015) Yuji Tamagawa et al.   LABORATORY INVESTIGATION

Conversion of one cell type into another: implications for understanding organ development, pathogenesis of cancer and generating cells for therapy: Figure 1

(2014) James L. Corbett et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas

(2014) Hideo Watanabe et al.   JOURNAL OF CLINICAL INVESTIGATION

Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett’s metaplasia

(2014) David H. Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Barrett oesophagus: lessons on its origins from the lesion itself

(2014) Stuart A. C. McDonald et al.   Nature Reviews Gastroenterology & Hepatology

Barrett's Esophagus

(2014) Stuart J. Spechler et al.   NEW ENGLAND JOURNAL OF MEDICINE

A pSMAD/CDX2 Complex Is Essential for the Intestinalization of Epithelial Metaplasia

(2014) Luigi Mari et al.   Cell Reports

Hydroxylase-dependent regulation of the NF-κB pathway

(2013) Carsten C. Scholz et al.   BIOLOGICAL CHEMISTRY

Endothelial PAS Domain Protein 1 Activates the Inflammatory Response in the Intestinal Epithelium to Promote Colitis in Mice

(2013) Xiang Xue et al.   GASTROENTEROLOGY

In oesophageal squamous cells exposed to acidic bile salt medium, omeprazole inhibits IL-8 expression through effects on nuclear factor-κB and activator protein-1

(2013) Xiaofang Huo et al.   GUT

Barrett Esophagus and Risk of Esophageal Cancer

(2013) Stuart Jon Spechler   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs

(2013) Geou-Yarh Liou et al.   JOURNAL OF CELL BIOLOGY

Barrett's metaplasia as a paradigm for understanding the development of cancer

(2012) Zoë D Burke et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Notch signaling pathway and Cdx2 expression in the development of Barrett's esophagus

(2012) Yuji Tamagawa et al.   LABORATORY INVESTIGATION

Current Status and Future Perspectives on the Etiology of Esophageal Adenocarcinoma

(2012) Aaron P. Thrift et al.   Frontiers in Oncology

Hypoxia and Inflammation

(2011) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Aberrant Epithelial–Mesenchymal Hedgehog Signaling Characterizes Barrett's Metaplasia

(2010) David H. Wang et al.   GASTROENTEROLOGY

Exogenous luminal nitric oxide exposure accelerates columnar transformation of rat esophagus

(2010) Hiroyuki Endo et al.   INTERNATIONAL JOURNAL OF CANCER

HIF-1 and HIF-2 transcription factors — Similar but not identical

(2010) Agnieszka Loboda et al.   MOLECULES AND CELLS

Gastroesophageal Reflux Might Cause Esophagitis Through a Cytokine-Mediated Mechanism Rather Than Caustic Acid Injury

(2009) Rhonda F. Souza et al.   GASTROENTEROLOGY

CDX2 hox gene product in a rat model of esophageal cancer

(2009) Giuseppe Ingravallo et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Overview of molecular testing in non-small-cell lung cancer: mutational analysis, gene copy number, protein expression and other biomarkers of EGFR for the prediction of response to tyrosine kinase inhibitors

(2009) T John et al.   ONCOGENE

Exogenous luminal nitric oxide exacerbates esophagus tissue damage in a reflux esophagitis model of rats

(2009) Fumitake Ishiyama et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Physicochemical basis for dilated intercellular spaces in non-erosive acid-damaged rabbit esophageal epithelium

(2008) N. A. Tobey et al.   DISEASES OF THE ESOPHAGUS

Pathophysiology of Gastroesophageal Reflux Disease

(2008) Roy C. Orlando   JOURNAL OF CLINICAL GASTROENTEROLOGY

Interdependent roles for hypoxia inducible factor and nuclear factor-κB in hypoxic inflammation

(2008) Cormac T. Taylor   JOURNAL OF PHYSIOLOGY-LONDON

Mechanisms of oxidant production in esophageal squamous cell and Barrett's cell lines

(2007) Linda A. Feagins et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY