iASPP induces EMT and cisplatin resistance in human cervical cancer through miR-20a-FBXL5/BTG3 signaling

Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer

(2017) Jiahui Xu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Changing paradigms in the systemic treatment of advanced cervical cancer

(2016) Krista S. Pfaendler et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

MiR-137 and miR-34a directly target Snail and inhibit EMT, invasion and sphere-forming ability of ovarian cancer cells

(2016) Peixin Dong et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Cisplatin resistance in gastric cancer cells is associated with HER2 upregulation-induced epithelial-mesenchymal transition

(2016) Dongsheng Huang et al.   Scientific Reports

Suppression of iASPP-dependent aggressiveness in cervical cancer through reversal of methylation silencing of microRNA-124

(2016) Peixin Dong et al.   Scientific Reports

EMT in cervical cancer: Its role in tumour progression and response to therapy

(2015) Rehana Qureshi et al.   CANCER LETTERS

FBXL5 Inhibits Metastasis of Gastric Cancer Through Suppressing Snail1

(2015) Weidong Wu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

BTG3 upregulation induces cell apoptosis and suppresses invasion in esophageal adenocarcinoma

(2015) Yuwen Du et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Reactivating p53 functions by suppressing its novel inhibitor iASPP: a potential therapeutic opportunity in p53 wild-type tumors

(2015) Peixin Dong et al.   Oncotarget

MiR-20a Promotes Cervical Cancer Proliferation and Metastasis In Vitro and In Vivo

(2015) Shan Zhao et al.   PLoS One

MicroRNA-101 targets EZH2, MCL-1 and FOS to suppress proliferation, invasion and stem cell-like phenotype of aggressive endometrial cancer cells

(2015) Yosuke Konno et al.   Oncotarget

Cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Oncogene iASPP enhances self-renewal of hematopoietic stem cells and facilitates their resistance to chemotherapy and irradiation

(2014) Yujiao Jia et al.   FASEB JOURNAL

Down-regulation of BTG3 promotes cell proliferation, migration and invasion and predicts survival in gastric cancer

(2014) X. L. Ren et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

The multiple facets of drug resistance: one history, different approaches

(2014) Evandro Niero et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

miRDB: an online resource for microRNA target prediction and functional annotations

(2014) Nathan Wong et al.   NUCLEIC ACIDS RESEARCH

Elevated expression of iASPP correlates with poor prognosis and chemoresistance/radioresistance in FIGO Ib1-IIa squamous cell cervical cancer

(2013) Liping Cao et al.   CELL AND TISSUE RESEARCH

SurvExpress: An Online Biomarker Validation Tool and Database for Cancer Gene Expression Data Using Survival Analysis

(2013) Raul Aguirre-Gamboa et al.   PLoS One

High Iodine Blocks a Notch/miR-19 Loop Activated by the BRAFV600E Oncoprotein and Restores the Response to TGFβ in Thyroid Follicular Cells

(2013) Cesar Seigi Fuziwara et al.   THYROID

Polycomb-Mediated Loss of miR-31 Activates NIK-Dependent NF-κB Pathway in Adult T Cell Leukemia and Other Cancers

(2012) Makoto Yamagishi et al.   CANCER CELL

iASPP and Chemoresistance in Ovarian Cancers: Effects on Paclitaxel-Mediated Mitotic Catastrophe

(2011) L. Jiang et al.   CLINICAL CANCER RESEARCH

Breast and cervical cancer in 187 countries between 1980 and 2010: a systematic analysis

(2011) Mohammad H Forouzanfar et al.   LANCET

The miRNA-17∼92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation

(2011) E Rao et al.   LEUKEMIA

RNA interference-mediated silencing of iASPP induces cell proliferation inhibition and G0/G1 cell cycle arrest in U251 human glioblastoma cells

(2010) Guilin Li et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis

(2009) Hong-li Yan et al.   EMBO JOURNAL

siRNA-mediated down-regulation of iASPP promotes apoptosis induced by etoposide and daunorubicin in leukemia cells expressing wild-type p53

(2009) Hang Liu et al.   LEUKEMIA RESEARCH

ARF antagonizes the ability of Miz-1 to inhibit p53-mediated transactivation

(2009) L Miao et al.   ONCOGENE

The estrogen receptor- -induced microRNA signature regulates itself and its transcriptional response

(2009) L. Castellano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aberrant Expression of Oncogenic and Tumor-Suppressive MicroRNAs in Cervical Cancer Is Required for Cancer Cell Growth

(2008) Xiaohong Wang et al.   PLoS One