ALX4, an epigenetically down regulated tumor suppressor, inhibits breast cancer progression by interfering Wnt/β-catenin pathway

β-catenin-mediated YAP signaling promotes human glioma growth

(2017) Yan Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Overexpression of Aristaless-Like Homeobox-4 Inhibits Proliferation, Invasion, and EMT in Hepatocellular Carcinoma Cells

(2017) Yao Shi et al.   ONCOLOGY RESEARCH

GSK-3β suppresses HCC cell dissociation in vitro by upregulating epithelial junction proteins and inhibiting Wnt/β-catenin signaling pathway

(2017) Jing-Hua Zhang et al.   Journal of Cancer

LHX6, An Independent Prognostic Factor, Inhibits Lung Adenocarcinoma Progression through Transcriptional Silencing of β-catenin

(2017) Juntang Yang et al.   Journal of Cancer

Epigenetic CpG Methylation of the Promoter and Reactivation of the Expression of GSTP1 by Astaxanthin in Human Prostate LNCaP Cells

(2016) Yuqing Yang et al.   AAPS Journal

Cancer statistics in China, 2015

(2016) Wanqing Chen et al.   CA-A CANCER JOURNAL FOR CLINICIANS

c-Myb Enhances Breast Cancer Invasion and Metastasis through the Wnt/ -Catenin/Axin2 Pathway

(2016) Y. Li et al.   CANCER RESEARCH

GPC5, a novel epigenetically silenced tumor suppressor, inhibits tumor growth by suppressing Wnt/β-catenin signaling in lung adenocarcinoma

(2016) S Yuan et al.   ONCOGENE

Pygo2 activates MDR1 expression and mediates chemoresistance in breast cancer via the Wnt/β-catenin pathway

(2016) Z-M Zhang et al.   ONCOGENE

HOXB13 and ALX4 induce SLUG expression for the promotion of EMT and cell invasion in ovarian cancer cells

(2015) Hong Yuan et al.   Oncotarget

High expression of SOX30 is associated with favorable survival in human lung adenocarcinoma

(2015) Fei Han et al.   Scientific Reports

Prevalence, risk factors, and prognosis of peritoneal metastasis from breast cancer

(2015) Serena Bertozzi et al.   SpringerPlus

β-Catenin Is Required for the Tumorigenic Behavior of Triple-Negative Breast Cancer Cells

(2015) Jinhua Xu et al.   PLoS One

Breast Cancer Biomarkers: Risk Assessment, Diagnosis, Prognosis, Prediction of Treatment Efficacy and Toxicity, and Recurrence

(2014) Amy Braden et al.   CURRENT PHARMACEUTICAL DESIGN

SNAIL1 combines competitive displacement of ASCL2 and epigenetic mechanisms to rapidly silence the EPHB3 tumor suppressor in colorectal cancer

(2014) Kerstin Rönsch et al.   Molecular Oncology

SOX30, a novel epigenetic silenced tumor suppressor, promotes tumor cell apoptosis by transcriptional activating p53 in lung cancer

(2014) F Han et al.   ONCOGENE

Epigenetic silencing of DACH1 induces loss of transforming growth factor-β1 antiproliferative response in human hepatocellular carcinoma

(2013) Hongbin Zhu et al.   HEPATOLOGY

Epigenetic silencing ofAristaless-like homeobox-4, a potential tumor suppressor gene associated with lung cancer

(2013) Wen-Bin Liu et al.   INTERNATIONAL JOURNAL OF CANCER

Wnt/beta-Catenin Signaling and Small Molecule Inhibitors

(2012) Andrey Voronkov et al.   CURRENT PHARMACEUTICAL DESIGN

Anandamide inhibits the Wnt/β-catenin signalling pathway in human breast cancer MDA MB 231 cells

(2012) Chiara Laezza et al.   EUROPEAN JOURNAL OF CANCER

The LIM Homeodomain Transcription Factor LHX6

(2012) Zichao Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The  -Catenin Destruction Complex

(2012) J. L. Stamos et al.   Cold Spring Harbor Perspectives in Biology

Deconstructing the ßcatenin destruction complex: mechanistic roles for the tumor suppressor APC in regulating Wnt signaling

(2011) David M. Roberts et al.   MOLECULAR BIOLOGY OF THE CELL

Cancer epigenetics reaches mainstream oncology

(2011) Manuel Rodríguez-Paredes et al.   NATURE MEDICINE

Targeting Wnt Signaling: Can We Safely Eradicate Cancer Stem Cells?

(2010) F. Takahashi-Yanaga et al.   CLINICAL CANCER RESEARCH

XPC Epigenetic Silence Coupled With p53 Alteration Has a Significant Impact on Bladder Cancer Outcome

(2010) Jin Yang et al.   JOURNAL OF UROLOGY

Molecular mechanisms of metastasis in breast cancer—clinical applications

(2010) Michal Mego et al.   Nature Reviews Clinical Oncology

Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells Mediate Metastasis and Poor Clinical Outcome in Inflammatory Breast Cancer

(2009) E. Charafe-Jauffret et al.   CLINICAL CANCER RESEARCH

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

ALX4 dysfunction disrupts craniofacial and epidermal development

(2009) Hulya Kayserili et al.   HUMAN MOLECULAR GENETICS

Loss of ALX4 expression in epithelial cells and adjacent stromal cells in breast cancer

(2009) H Chang et al.   JOURNAL OF CLINICAL PATHOLOGY

Lung cancer epigenetics and genetics

(2008) Angela Risch et al.   INTERNATIONAL JOURNAL OF CANCER