PSAT1 is regulated by ATF4 and enhances cell proliferation via the GSK3β/β-catenin/cyclin D1 signaling pathway in ER-negative breast cancer

Phosphoserine aminotransferase 1 is associated to poor outcome on tamoxifen therapy in recurrent breast cancer

(2017) Tommaso De Marchi et al.   Scientific Reports

A High-Quality Biobank Supports Breast Cancer Research in Harbin, China

(2016) Guangwen Zhang et al.   BIOPRESERVATION AND BIOBANKING

Psat1-Dependent Fluctuations in α-Ketoglutarate Affect the Timing of ESC Differentiation

(2016) In-Young Hwang et al.   Cell Metabolism

Overexpression of Phosphoserine Aminotransferase 1 (PSAT1) Predicts Poor Prognosis and Associates with Tumor Progression in Human Esophageal Squamous Cell Carcinoma

(2016) Bingyan Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

A High-Quality Biobank Supports Breast Cancer Research in Harbin, China

(2016) Guangwen Zhang et al.   Biopreservation and Biobanking

Crosstalk between ATF4 and MTA1/HDAC1 promotes osteosarcoma progression

(2016) Heng Zeng et al.   Oncotarget

Phosphoglycerate kinase-1 is a predictor of poor survival and a novel prognostic biomarker of chemoresistance to paclitaxel treatment in breast cancer

(2015) S Sun et al.   BRITISH JOURNAL OF CANCER

Expression of ribosome-binding protein 1 correlates with shorter survival in Her-2 positive breast cancer

(2015) Xiaoshuan Liang et al.   CANCER SCIENCE

MicroRNA-340 Inhibits Esophageal Cancer Cell Growth and Invasion by Targeting Phosphoserine Aminotransferase 1

(2015) Shuo Yan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

NRF2 regulates serine biosynthesis in non–small cell lung cancer

(2015) Gina M DeNicola et al.   NATURE GENETICS

Calcitriol restores antiestrogen responsiveness in estrogen receptor negative breast cancer cells: A potential new therapeutic approach

(2014) Nancy Santos-Martínez et al.   BMC CANCER

Akt2 Mediates TGF-�1-Induced Epithelial to Mesenchymal Transition by Deactivating GSK3�/Snail Signaling Pathway in Renal Tubular Epithelial Cells

(2014) Aiping Lan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

PSAT1 regulates cyclin D1 degradation and sustains proliferation of non-small cell lung cancer cells

(2014) Yi Yang et al.   INTERNATIONAL JOURNAL OF CANCER

Activating Transcription Factor 4 Promotes Esophageal Squamous Cell Carcinoma Invasion and Metastasis in Mice and Is Associated with Poor Prognosis in Human Patients

(2014) Hongwu Zhu et al.   PLoS One

Serine Metabolism: Some Tumors Take the Road Less Traveled

(2013) Ralph J. DeBerardinis   Cell Metabolism

Activating transcription factor 4 increases chemotherapeutics resistance of human hepatocellular carcinoma

(2012) Zhuhong Zhang et al.   CANCER BIOLOGY & THERAPY

Wnt signaling from membrane to nucleus: β-catenin caught in a loop

(2012) Cara Jamieson et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Activating Transcription Factor 4 Confers a Multidrug Resistance Phenotype to Gastric Cancer Cells through Transactivation of SIRT1 Expression

(2012) Hongwu Zhu et al.   PLoS One

Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation

(2012) J. Ye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of ATF4 in regulation of autophagy and resistance to drugs and hypoxia

(2011) Tomasz Rzymski et al.   CELL CYCLE

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

(2011) Richard Possemato et al.   NATURE

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

(2011) Jason W Locasale et al.   NATURE GENETICS

Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis

(2010) Sirkku Pollari et al.   BREAST CANCER RESEARCH AND TREATMENT

The Role of ATF4 Stabilization and Autophagy in Resistance of Breast Cancer Cells Treated with Bortezomib

(2009) M. Milani et al.   CANCER RESEARCH

Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells

(2008) Nadia Vié et al.   Molecular Cancer