Benzo[g]quinazolin-based scaffold derivatives as dual EGFR/HER2 inhibitors

Design, synthesis and biological evaluation of pyrazolyl-nitroimidazole derivatives as potential EGFR/HER-2 kinase inhibitors

(2016) Xiang-Xiang Tao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis and antitumor activity of novel pyrazolo[3,4-d]pyrimidine derivatives as EGFR-TK inhibitors

(2016) Mohamed A. Abdelgawad et al.   BIOORGANIC CHEMISTRY

Design, synthesis and biological evaluation of novel EGFR/HER2 dual inhibitors bearing a oxazolo[4,5-g]quinazolin-2(1H)-one scaffold

(2016) Siyuan Yin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Afatinib beyond progression in patients with non-small-cell lung cancer following chemotherapy, erlotinib/gefitinib and afatinib: phase III randomized LUX-Lung 5 trial

(2015) M. Schuler et al.   ANNALS OF ONCOLOGY

Targeting EGFR/HER2 tyrosine kinases with a new potent series of 6-substituted 4-anilinoquinazoline hybrids: Design, synthesis, kinase assay, cell-based assay, and molecular docking

(2015) Ahmed Elkamhawy et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel Quinazoline Derivatives Bearing Various 4-Aniline Moieties as Potent EGFR Inhibitors with Enhanced Activity Against NSCLC Cell Lines

(2015) Changyan Wang et al.   Chemical Biology & Drug Design

Regioselective synthesis of 6-aryl-benzo[h][1,2,4]-triazolo[5,1-b]quinazoline-7,8-diones as potent antitumoral agents

(2013) Liqiang wu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Impact of EGFR Inhibitor in Non–Small Cell Lung Cancer on Progression-Free and Overall Survival: A Meta-Analysis

(2013) Chee Khoon Lee et al.   JNCI-Journal of the National Cancer Institute

Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives

(2009) Olayinka O. Ajani et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Predictive value of EGFR and HER2 overexpression in advanced non-small-cell lung cancer

(2009) F R Hirsch et al.   ONCOGENE