Symmetric molecules with 1,4-triazole moieties as potent inhibitors of tumour-associated lactate dehydrogenase-A

Lactate dehydrogenase inhibitors can reverse inflammation induced changes in colon cancer cells

(2017) Marcella Manerba et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Discovery of human lactate dehydrogenase A (LDHA) inhibitors as anticancer agents to inhibit the proliferation of MG-63 osteosarcoma cells

(2017) Aiping Fang et al.   MedChemComm

Lactate dehydrogenase inhibition: exploring possible applications beyond cancer treatment

(2016) Giuseppina Di Stefano et al.   Future Medicinal Chemistry

Kinetic characterization of lactate dehydrogenase in normal and malignant human breast tissues

(2015) Abdolhassan Talaiezadeh et al.   Cancer Cell International

Lactate dehydrogenase inhibitors sensitize lymphoma cells to cisplatin without enhancing the drug effects on immortalized normal lymphocytes

(2015) Marcella Manerba et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Evaluation of the anti-tumor effects of lactate dehydrogenase inhibitor galloflavin in endometrial cancer cells

(2015) Xiaoyun Han et al.   Journal of Hematology & Oncology

Recent Update on Human Lactate Dehydrogenase Enzyme 5 (hLDH5) Inhibitors: A Promising Approach for Cancer Chemotherapy

(2015) Reshma Rani et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inhibition of lactate dehydrogenase activity as an approach to cancer therapy

(2014) Luigi Fiume et al.   Future Medicinal Chemistry

Toward Metal Complexes That Can Directionally Walk Along Tracks: Controlled Stepping of a Molecular Biped with a Palladium(II) Foot

(2014) Jonathon E. Beves et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Galloflavin suppresses lactate dehydrogenase activity and causes MYC downregulation in Burkitt lymphoma cells through NAD/NADH-dependent inhibition of sirtuin-1

(2013) Marina Vettraino et al.   ANTI-CANCER DRUGS

Identification of substituted 2-thio-6-oxo-1,6-dihydropyrimidines as inhibitors of human lactate dehydrogenase

(2013) Peter S. Dragovich et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

1,3,5-Trisubstituted benzenes as fluorescent photoaffinity probes for human carbonic anhydrase II capture

(2013) Partha Sarathi Addy et al.   CHEMICAL COMMUNICATIONS

Targeting lactate metabolism for cancer therapeutics

(2013) Joanne R. Doherty et al.   JOURNAL OF CLINICAL INVESTIGATION

Fragment Growing and Linking Lead to Novel Nanomolar Lactate Dehydrogenase Inhibitors

(2013) Anna Kohlmann et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and evaluation of novel benzimidazole derivatives as antimicrobial agents

(2013) Deepkumar Joshi et al.   MEDICINAL CHEMISTRY RESEARCH

Targeting cellular metabolism to improve cancer therapeutics

(2013) Y Zhao et al.   Cell Death & Disease

Galloflavin, a new lactate dehydrogenase inhibitor, induces the death of human breast cancer cells with different glycolytic attitude by affecting distinct signaling pathways

(2012) F. Farabegoli et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Design and Synthesis of Novel Lactate Dehydrogenase A Inhibitors by Fragment-Based Lead Generation

(2012) Richard A. Ward et al.   JOURNAL OF MEDICINAL CHEMISTRY

Galloflavin (CAS 568-80-9): A Novel Inhibitor of Lactate Dehydrogenase

(2011) Marcella Manerba et al.   ChemMedChem

Carboxylic Acid-Promoted Copper(I)-Catalyzed Azide−Alkyne Cycloaddition

(2010) Changwei Shao et al.   JOURNAL OF ORGANIC CHEMISTRY

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

(2010) A. Le et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA