The immunoproteasome is induced by cytokines and regulates apoptosis in human islets

Kinase-Independent Small-Molecule Inhibition of JAK-STAT Signaling

(2015) Danny Hung-Chieh Chou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Lipotoxic Stress Induces Pancreaticβ-Cell Apoptosis through Modulation of Bcl-2 Proteins by the Ubiquitin-Proteasome System

(2015) Sara A. Litwak et al.   Journal of Diabetes Research

Regulated protein turnover: snapshots of the proteasome in action

(2014) Sucharita Bhattacharyya et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Proteasome Dysfunction Mediates High Glucose-Induced Apoptosis in Rodent Beta Cells and Human Islets

(2014) Christophe Broca et al.   PLoS One

Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and  -cell protection

(2014) D. P. Christensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of Histone Deacetylase 3 Protects Beta Cells from Cytokine-Induced Apoptosis

(2012) Danny Hung-Chieh Chou et al.   CHEMISTRY & BIOLOGY

Microarray analysis of isolated human islet transcriptome in type 2 diabetes and the role of the ubiquitin–proteasome system in pancreatic beta cell dysfunction

(2012) Marco Bugliani et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The Immunoproteasomes Regulate LPS-Induced TRIF/TRAM Signaling Pathway in Murine Macrophages

(2011) Julia Reis et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Proteasome activator PA28γ stimulates degradation of GSK3-phosphorylated insulin transcription activator MAFA

(2011) Kenichi Kanai et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Immunoproteasomes Preserve Protein Homeostasis upon Interferon-Induced Oxidative Stress

(2010) Ulrike Seifert et al.   CELL

Mitochondrial uncoupling protein 2 in pancreatic β-cells

(2010) M. D. Brand et al.   DIABETES OBESITY & METABOLISM

Targeting the proteasome: partial inhibition of the proteasome by bortezomib or deletion of the immunosubunit LMP7 attenuates experimental colitis

(2010) N. Schmidt et al.   GUT

Prevention of Experimental Colitis by a Selective Inhibitor of the Immunoproteasome

(2010) M. Basler et al.   JOURNAL OF IMMUNOLOGY

Autophagy in human type 2 diabetes pancreatic beta cells

(2009) M. Masini et al.   DIABETOLOGIA

Quantification of protein modification by oxidants

(2009) Clare L. Hawkins et al.   FREE RADICAL BIOLOGY AND MEDICINE

A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis

(2009) Tony Muchamuel et al.   NATURE MEDICINE

Emerging roles for the ubiquitin-proteasome system and autophagy in pancreatic β-cells

(2008) Taila Hartley et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM