A Novel NF-κB Inhibitor, Edasalonexent (CAT-1004), in Development as a Disease-Modifying Treatment for Patients With Duchenne Muscular Dystrophy: Phase 1 Safety, Pharmacokinetics, and Pharmacodynamics in Adult Subjects

Synthesis and Characterization of Fatty Acid Conjugates of Niacin and Salicylic Acid

(2016) Chi B. Vu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Musculoskeletal simulation can help explain selective muscle degeneration in Duchenne muscular dystrophy

(2015) Xiao Hu et al.   MUSCLE & NERVE

CAT-1004, an oral agent targeting NF-κB in development for treatment of Duchenne muscular dystrophy: Phase 1/2 study design

(2015) J. Donovan et al.   NEUROMUSCULAR DISORDERS

Immune-mediated pathology in Duchenne muscular dystrophy

(2015) Amy S. Rosenberg et al.   Science Translational Medicine

TNF-α-Induced microRNAs Control Dystrophin Expression in Becker Muscular Dystrophy

(2015) Alyson A. Fiorillo et al.   Cell Reports

Ataluren treatment of patients with nonsense mutation dystrophinopathy

(2014) Katharine Bushby et al.   MUSCLE & NERVE

Targeting inflammation in the treatment of type 2 diabetes: time to start

(2014) Marc Y. Donath   NATURE REVIEWS DRUG DISCOVERY

Omega-3 Free Fatty Acids Suppress Macrophage Inflammasome Activation by Inhibiting NF-κB Activation and Enhancing Autophagy

(2014) Yolanda Williams-Bey et al.   PLoS One

The Effects of Salsalate on Glycemic Control in Patients With Type 2 Diabetes

(2013) Allison B. Goldfine   ANNALS OF INTERNAL MEDICINE

Eteplirsen for the treatment of Duchenne muscular dystrophy

(2013) Jerry R. Mendell et al.   ANNALS OF NEUROLOGY

Wasting mechanisms in muscular dystrophy

(2013) Jonghyun Shin et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

All-Cause Mortality and Cardiovascular Outcomes With Prophylactic Steroid Therapy in Duchenne Muscular Dystrophy

(2013) Gernot Schram et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Long-term benefits and adverse effects of intermittent versus daily glucocorticoids in boys with Duchenne muscular dystrophy

(2012) V. Ricotti et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Implications of glucocorticoid therapy in idiopathic inflammatory myopathies

(2012) Beatriz Y. Hanaoka et al.   Nature Reviews Rheumatology

Effects of DHA- Rich n-3 Fatty Acid Supplementation on Gene Expression in Blood Mononuclear Leukocytes: The OmegAD Study

(2012) Inger Vedin et al.   PLoS One

A systematic review of salicylates in foods: Estimated daily intake of a Scottish population

(2011) Adrian Wood et al.   MOLECULAR NUTRITION & FOOD RESEARCH

NF-κB Negatively Impacts the Myogenic Potential of Muscle-derived Stem Cells

(2011) Aiping Lu et al.   MOLECULAR THERAPY

Natural salicylates: foods, functions and disease prevention

(2011) Garry G. Duthie et al.   Food & Function

GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects

(2010) Da Young Oh et al.   CELL

Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells

(2009) Mark Bouwens et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Mechanisms of Muscle Atrophy Induced by Glucocorticoids

(2009) O. Schakman et al.   HORMONE RESEARCH

Nuclear factor-kappa B signaling in skeletal muscle atrophy

(2008) Hong Li et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

NF-κB signaling in skeletal muscle: prospects for intervention in muscle diseases

(2008) Foteini Mourkioti et al.   JOURNAL OF MOLECULAR MEDICINE-JMM