Article
Oncology
Emrah Celtikci, Muammer Melih Sahin, Mustafa Caglar Sahin, Emetullah Cindil, Zuhal Demirtas, Hakan Emmez
Summary: This retrospective study aimed to determine the necessity of intraoperative MRI scans following endoscopic endonasal pituitary adenoma surgery. The results show that for adenomas limited in the sellae and not invading the cavernous sinus, an IO-MRI scan is not necessary, but it is strongly recommended if there is any suprasellar and parasellar extension and/or cavernous sinus invasion.
FRONTIERS IN ONCOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Chun-Qiu Su, Bin-Bin Wang, Wen-Tian Tang, Chao Tao, Peng Zhao, Min-Hong Pan, Xun-Ning Hong, Wen-Tao Hu, Yong-Ming Dai, Hai-Bin Shi, Shan-Shan Lu
Summary: This study evaluated the ability of diffusion-relaxation correlation spectrum imaging (DR-CSI) to predict the consistency and extent of resection (EOR) of pituitary adenomas (PAs). DR-CSI was found to be a promising tool for predicting the consistency and extent of resection of PAs, which has clinical relevance.
EUROPEAN RADIOLOGY
(2023)
Article
Clinical Neurology
Rupa G. Juthani, Anne S. Reiner, Ankur R. Patel, Aimee Cowan, Marie Roguski, Katherine S. Panageas, Eliza B. Geer, Sasan Karimi, Marc A. Cohen, Viviane Tabar
Summary: The study evaluated the safety and efficacy of iMRI for pituitary adenoma resection, comparing endoscopic transsphenoidal and microscopic transsphenoidal approaches. Results showed that iMRI can improve the extent of resection for pituitary adenomas while preserving hormone function, with low rates of postoperative complications.
JOURNAL OF NEUROSURGERY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yan Bai, Yu Shen, Rushi Chen, Xianchang Zhang, Mathias Nittka, Gregor Koerzdoerfer, Qiyong Gong, Meiyun Wang
Summary: Magnetic resonance fingerprinting (MRF) can effectively differentiate gonadotroph from non-gonadotroph pituitary macroadenomas, guiding treatment decisions.
EUROPEAN RADIOLOGY
(2021)
Review
Clinical Neurology
John J. Y. Zhang, Jia Xu Lim, Keng Siang Lee, Ramez W. Kirollos, Jai Prashanth Rao
Summary: The use of iMRI in transsphenoidal surgery significantly improves the gross total resection (GTR) rate and achieves comparable benefits for functioning and nonfunctioning pituitary adenomas. Satisfactory endocrinologic and visual outcomes are also achieved.
WORLD NEUROSURGERY
(2022)
Article
Gastroenterology & Hepatology
Issei Hasegawa, Takeshi Yamamura, Hiroto Suzuki, Keiko Maeda, Tsunaki Sawada, Yasuyuki Mizutani, Eri Ishikawa, Takuya Ishikawa, Naomi Kakushima, Kazuhiro Furukawa, Eizaburo Ohno, Hiroki Kawashima, Masanao Nakamura, Mitsuhiro Fujishiro
Summary: The study found that while the ADR was similar between the LCI and WLI groups, the LCI group showed significantly lower AMR, especially for diminutive adenomas and nonpolypoid lesions. This suggests that LCI has an advantage in reducing adenoma miss rate.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Clinical Neurology
Hyung-Chul Lee, Hyun-Kyu Yoon, Jung Hee Kim, Yong Hwy Kim, Hee-Pyoung Park
Summary: The study suggests that preoperative steroid administration may not be necessary for patients without adrenal insufficiency undergoing endoscopic transsphenoidal surgery for nonfunctioning pituitary adenomas, as it does not affect the pituitary hormone levels postoperatively. However, further large-scale studies are needed to determine the impact of preoperative steroid administration on clinically meaningful events such as perioperative AI and postoperative 3-month ACTH deficiency in these patients.
JOURNAL OF NEUROSURGERY
(2021)
Article
Clinical Neurology
Lea M. Alhilali, Andrew S. Little, Kevin C. J. Yuen, Jae Lee, Timothy K. Ho, Saeed Fakhran, William L. White
Summary: In this study of 102 patients undergoing microscopic transsphenoidal resection of a pituitary adenoma, early postoperative MRI showed high sensitivity and specificity for detecting residual tumors, with better reliability than late postoperative MRI. Early MRI identified 4 residual tumors that were missed by intraoperative assessment and late MRI, providing important guidance for reoperation in select patients.
JOURNAL OF NEUROSURGERY
(2021)
Article
Neurosciences
Tianshun Feng, Yi Fang, Zhijie Pei, Ziqi Li, Hongjie Chen, Pengwei Hou, Liangfeng Wei, Renzhi Wang, Shousen Wang
Summary: This study demonstrates the potential of a CNN model to accurately assess sellar floor invasion in pituitary adenoma, with high accuracy and excellent performance.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Endocrinology & Metabolism
Kunzhe Lin, Ran Zeng, Shuwen Mu, Yinghong Lin, Shousen Wang
Summary: This study developed a nomogram to predict delayed hyponatremia after transsphenoidal surgery for pituitary adenoma. By incorporating clinical variables and magnetic resonance imaging scans, the nomogram provides individualized prediction and demonstrates clinical usefulness.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yang Zhang, Junkai Zheng, Zhouyang Huang, Yuen Teng, Chaoyue Chen, Jianguo Xu
Summary: This study aimed to investigate whether morphological changes and delta-radiomics of the optic chiasm obtained from routine MRI could help predict postoperative visual recovery of pituitary adenoma patients. A total of 130 patients were enrolled, and it was found that postoperative morphological changes of the optic chiasm were not significantly associated with visual outcome, while the delta-radiomics model showed good performance in predicting visual recovery.
EUROPEAN RADIOLOGY
(2023)
Article
Clinical Neurology
Andrew S. Little, Varun R. Kshettry, Marc R. Rosen, Ryan M. Rehl, Timothy W. Haegen, Mindy R. Rabinowitz, Gurston G. Nyquist, Pablo F. Recinos, Raj Sindwani, Troy D. Woodard, Christopher J. Farrell, Griffin D. Santarelli, John Milligan, James J. Evans
Summary: The study found that postoperative prophylactic oral antibiotics did not result in superior sinonasal quality of life compared with placebo among patients who underwent standard endoscopic transsphenoidal surgery.
Article
Clinical Neurology
Martin Cerny, Jan Kybic, Martin Majovsky, Vojtech Sedlak, Karin Pirgl, Eva Misiorzova, Radim Lipina, David Netuka
Summary: This study developed a fully automated system for pituitary adenoma segmentation from MRI scans. Two artificial neural networks were trained on 394 patient scans, and achieved good results on the largest dataset to date. The system demonstrated accuracy and utility for clinical applications, and discussion of future clinical use was included.
NEUROSURGICAL REVIEW
(2023)
Article
Oncology
Kiyohisa Kamimura, Masanori Nakajo, Manisha Bohara, Daigo Nagano, Yoshihiko Fukukura, Shingo Fujio, Tomoko Takajo, Kazuhiro Tabata, Takashi Iwanaga, Hiroshi Imai, Marcel Dominik Nickel, Takashi Yoshiura
Summary: A study investigated the predictive value of quantitative pharmacokinetic analysis of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in determining the consistency of pituitary adenomas. The volume of extravascular extracellular space per unit volume of tissue derived from DCE-MRI was found to have predictive value for consistency of pituitary adenomas, with a positive correlation with histopathologic collagen content. The study suggests that this parameter can be useful for planning transsphenoidal surgery for pituitary adenomas.
Article
Surgery
Junhao Zhu, Guodao Wen, Chao Tang, Zixiang Cong, Xiangming Cai, Jin Yang, Chiyuan Ma
Summary: The results of this study show that there is no significant difference in surgical outcomes and post-operative sinonasal quality of life between the OETA and BETA approaches.
FRONTIERS IN SURGERY
(2022)
Article
Clinical Neurology
Shabari Girishan, Manjari Tripathi, Ajay Garg, Ramesh Doddamani, Jitin Bajaj, Bhargavi Ramanujam, P. Sarat Chandra
JOURNAL OF NEUROSURGERY-PEDIATRICS
(2020)
Article
Clinical Neurology
Madhu Rajeshwari, Priyadarsani Subramanian, Vaishali Suri, Aruna Nambirajan, Ajay Garg, Deepti Vibha, Manoj Phalak, Mehar Chand Sharma
Article
Clinical Neurology
Niveditha Manjunath, Prerana Jha, Jyotsna Singh, Amol Raheja, Kavneet Kaur, Ashish Suri, Ajay Garg, Mehar Chand Sharma, Chitra Sarkar, Madan Mohan, Kalaivani Mani, Vaishali Suri
Summary: The study found differences in frequency and location of pediatric and adult DMGs, mutually exclusive H3K27M mutation with IDH mutation, and excellent concordance between immunohistochemistry (H-scoring) and sequencing for H3K27M mutation evaluation. However, prognosis remains poor regardless of age, location, and H3K27M status. Adjuvant therapy significantly impacts survival in adults but not in pediatric cases.
NEUROLOGICAL SCIENCES
(2021)
Review
Clinical Neurology
Jeyaseelan Nadarajah, Leve Joseph Devarajan Sebastian, K. T. Puneeth, Anuj Prabhakar, Ajay Garg, S. B. Gaikwad, Amandeep Kumar
INTERVENTIONAL NEURORADIOLOGY
(2020)
Article
Neurosciences
Jyotirmoy Banerjee, Soumil Dey, Aparna Banerjee Dixit, Ramesh Doddamani, Meher Chand Sharma, Ajay Garg, P. Sarat Chandra, Manjari Tripathi
FRONTIERS IN CELLULAR NEUROSCIENCE
(2020)
Article
Clinical Neurology
Dhruv Sharma, Dattaraj Parmanand Sawarkar, Pankaj Kumar Singh, Shashank Sharad Kale, Leve Joseph, Ajay Garg, Amandeep Kumar, Satish Verma, Ramesh Doddamani, Rajesh Meena, Sarat P. Chandra
Summary: This study analyzed the pedicle width and the relationship between the vertebral artery and transverse foramen in the subaxial cervical spine to determine safety margin in cases of lateral pedicular breach. The results showed that parameters such as PW, LPVA, OR, and SM may prevent vertebral artery injuries in cases of cervical pedicle breach.
WORLD NEUROSURGERY
(2022)
Editorial Material
Clinical Neurology
Ayush Agarwal, Divyani Garg, Venugopalan Y. Vishnu, Ajay Garg, M. V. Padma Srivastava
Article
Radiology, Nuclear Medicine & Medical Imaging
Surya Kant, Bheru Dan Charan, Vinay Goel, Sumanta Das, Saumya Sahu, Rajiv Sharma, Sachin Borkar, Leve Joseph Devaranjan Sebastian, Ajay Garg
EGYPTIAN JOURNAL OF RADIOLOGY AND NUCLEAR MEDICINE
(2023)
Article
Clinical Neurology
Simranjeet Singh, Shweta Kedia, Ajay Garg, Hemanth Kumar, Gaurav Singh
Summary: DNET is a Grade 1 tumor that can cause drug-resistant tumor-associated epilepsy, presenting diagnostic challenges. Early surgery remains the mainstay of treatment, while conservative approaches may result in catastrophic consequences.
INTERDISCIPLINARY NEUROSURGERY-ADVANCED TECHNIQUES AND CASE MANAGEMENT
(2021)
Article
Neuroimaging
Leve Joseph Devarajan Sebastian, Chirag Ahuja, Sabarish Sekar, Santhakumar Senthilvelan, Karthik Kulanthaivelu, Vivek Lanka, Vinay Goel, Sarita Mohapatra, Chirag Jain, S. Senthilkumaran, Ajay Garg, Parthiban Balasundaram, Ajay Kumar, Aarti Kapil, Chandrasekharan Kesavadas, Vivek Gupta
NEURORADIOLOGY JOURNAL
(2020)
Letter
Clinical Neurology
Ayush Agarwal, Pradeep S. Reddy, Venugopalan Y. Vishnu, Ajay Garg
JOURNAL OF NEUROSCIENCES IN RURAL PRACTICE
(2020)
Meeting Abstract
Clinical Neurology
Anand Kumar, Mamta Singh, Ajay Garg, V. Y. Vishnu, Vinay Goyal, M. V. Padma Srivastava
Article
Clinical Neurology
Divyani Garg, Achal Kumar Srivastava, Ashok Kumar Jaryal, Roopa Rajan, Akanksha Singh, Awadh Kishor Pandit, Deepti Vibha, Garima Shukla, Ajay Garg, Ravindra Mohan Pandey, Kameshwar Prasad
MOVEMENT DISORDERS CLINICAL PRACTICE
(2020)
Article
Clinical Neurology
Pankhuri Mittal, Hitesh Verma, Rabia Monga, Ajay Garg, Alok Thakar
INTERDISCIPLINARY NEUROSURGERY-ADVANCED TECHNIQUES AND CASE MANAGEMENT
(2020)
Meeting Abstract
Clinical Neurology
Kavneet Kaur, Aruna Nambirajan, Prit Benny Malgulwar, Vaishali Suri, Mehar Chand Sharma, Ajay Garg, Chitra Sarkar
Review
Clinical Neurology
Oday Atallah, Amr Badary, Yasser F. Almealawy, Vivek Sanker, Wireko Andrew Awuah, Toufik Abdul-Rahman, Sura N. Alrubaye, Bipin Chaurasia
Summary: This study investigates unexpected deaths resulting from primary brain tumors and analyzes the contributing variables. The findings reveal that unexpected deaths are a complex phenomenon, with headache being the most common initial symptom and meningiomas and astrocytomas being the most common lesions.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Alexandra E. Quimby, Mandy K. Salmon, Christopher H. Zhao, John Y. K. Lee, Douglas C. Bigelow, Michael J. Ruckenstein, Jason A. Brant
Summary: The study found that socioeconomic factors including race, health insurance, and income have an impact on the quality of life at the time of vestibular schwannoma diagnosis. Black/African American and uninsured/self-pay patients had lower quality of life, while patients with higher income had higher quality of life.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Review
Clinical Neurology
Arosha S. Dissanayake, Kwok M. Ho, Timothy J. Phillips, Stephen Honeybul, Graeme J. Hankey
Summary: This study systematically reviews models that aim to provide patient-specific predictions of pre-treatment rebleeding risk in patients with aneurysmal subarachnoid hemorrhage. The reported discriminative performance of the models varied, and no model showed consistently low bias risk and clinical applicability in all domains. Only one model was formulated using a patient cohort that underwent contemporary, evidence-based aneurysm treatment practices, but this model lacked calibration or clinical utility.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Colin Kok Ann Teo, Yilong Zheng, Jeremy Bingyuan Lin, Hock Luen Teoh, Bernard Poon Lap Chan, Vijay Kumar Sharma, Kejia Teo, Vincent Diong Weng Nga, Tseng Tsai Yeo
Summary: This study retrospectively reviewed the clinical characteristics and outcomes after surgical revascularization for adult Moyamoya disease (MMD) in a Southeast Asian cohort. The incidence of postoperative transient ischemic attack (TIA)/stroke was 25.9%, with most cases occurring within 7 days postoperatively. Risk factors for 30-day postoperative TIA/stroke included a higher number of preoperative TIAs/strokes and indirect revascularization.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Cheng-Chi Lee, Abel Po-Hao Huang, Ching-Chang Chen, Zhuo-Hao Liu, Mun-Chun Yeap, Ko-Ting Chen, Peng-Wei Hsu, Kuo-Chen Wei, Chun-Ting Chen, Yu-Chi Wang, Ting-Wei Chang, Chi-Cheng Chuang
Summary: Using a novel portable neuroendoscopic system for minimally invasive evacuation of intracerebral hemorrhage (ICH) has shown positive outcomes in reducing hematoma volume and improving neurological function without any death or rebleeding incidents.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Michael M. Haglund, Bruce M. McCormack, Daniel M. Williams, Alexander C. Lemons, Erik M. Summerside
Summary: This study evaluated the long-term radiographic outcomes of patients receiving tissue-sparing posterior cervical fusion (PCF) for the treatment of pseudarthrosis. The results showed that patients achieved rates of arthrodesis similar to open PCF, with fewer postoperative complications and long-term soft tissue pain.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Dong-Dong Meng, Zhe Ruan, Yong-Lan Tang, Zhao-Hua Ji, Yue Su, Tuo Xu, Bo-Zhou Cui, Da-Lin Ren, Ting Chang, Qian Yang
Summary: Depression symptom level, MG severity classification and family's monthly per capita income are independent factors related to the caregivers' disease family burden for MG patients. The daily activity burden of the family and the economic burden of the family were the heaviest among the six dimensions of the caregivers' family disease burdens.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Tugba Ozudogru Celik, Umit Gorgulu, Safiye Gul Kenar, Nadide Koca, Elif Yalcin, Ipek Koymen, Evren Yasar
Summary: This study investigated the forward head posture (FHP), thoracic kyphosis, and their relationship in individuals with migraine compared to healthy controls. The results showed that patients with migraine had a greater FHP and thoracic kyphosis. This suggests that a 3-dimensional objective measurement could be a reliable tool for evaluating posture analysis in clinical practice.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Jason A. Chen, Ari D. Kappel, Erickson F. Torio, David I. Bass, Abdullah Feroze, Nirav J. Patel
Summary: This report presents a case of a 63-year-old woman with a ruptured giant ICA terminus aneurysm, who underwent coil embolization followed by parent vessel sacrifice and high-flow bypass.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Sandeep Kandregula, Sneha Sai Mannam, Shahbaz Saad, Saarang Patel, Visish M. Srinivasan
Summary: A 39-year-old female with a history of smoking and a family predisposition to unruptured aneurysms presented with clinical symptoms of intermittent right-sided headaches, flashes of light, and pulsatile tinnitus. Diagnostic evaluations identified a right occipital arteriovenous malformation (AVM). Treatment involved partial embolization of primary arterial feeders followed by surgical resection, resulting in a successful outcome.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Ari D. Kappel, Jason A. Chen, Joshua I. Chalif, David I. Bass, Erickson F. Torio, Abdullah H. Feroze, Nirav J. Patel
Summary: A 48-year-old male with progressive congestive myelopathy underwent surgical clipping to treat a craniocervical DAVF. Intraoperatively, ICG was used to confirm the solitary inflow.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Aryeh Zolin, Cenai Zhang, Hwai Ooi, Harini Sarva, Hooman Kamel, Neal S. Parikh
Summary: In people with Parkinson's disease, comorbid liver fibrosis is associated with more rapid cognitive decline across multiple domains.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)