Optimization of ion exchange sigmoidal gradients using hybrid models: Implementation of quality by design in analytical method development

Published 2017 View Full Article

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Title
Optimization of ion exchange sigmoidal gradients using hybrid models: Implementation of quality by design in analytical method development
Authors
Keywords
Quality by Design (QbD), Analytical method development, Mechanistic model, Ion exchange chromatography, Monoclonal antibody (mAb)
Journal
JOURNAL OF CHROMATOGRAPHY A
Volume 1491, Issue -, Pages 145-152
Publisher
Elsevier BV
Online
2017-02-28
DOI
10.1016/j.chroma.2017.02.058

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