Article
Food Science & Technology
Zala Gombac, Ilja Gasan Osojnik Crnivec, Mihaela Skrt, Katja Istenic, Andreja Knez Knafelj, Igor Pravst, Natasa Poklar Ulrih
Summary: The study focused on preparing stable encapsulates of lutein and lutein esters using feasible techniques. Fine suspensions and lecithin emulsions showed high encapsulation efficiencies and superior stability over the course of 250 days of storage under specific conditions.
Article
Pharmacology & Pharmacy
Yu-Ning Teng, Li-Hung Chen, Yi-Hung Chen (kui vavulengan)
Summary: Drug efflux transporters are closely related to drug resistance issues. This study evaluated the inhibitory effects of Tween 80 on P-gp and MRP1, and the findings suggest that Tween 80 could be a potential candidate for combinatorial regimens in drug resistance.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
(2022)
Article
Multidisciplinary Sciences
Ke Mo, Yu Zhang, Zheng Dong, Yuhang Yang, Xiaoqiang Ma, Ben L. Feringa, Depeng Zhao
Summary: Scientists have designed synthetic molecular motors that can be driven by chemical energy and have intrinsic control over the direction of rotation, simple autonomous motion, and near-perfect unidirectionality. This study demonstrates the potential for future generations of multicomponent machines to perform mechanical functions.
Article
Engineering, Biomedical
Ruslan Garifullin, Mustafa O. Guler
Summary: This review discusses the use of self-assembling peptide molecules and electroactive units in supramolecular functional electronic and optical materials, with potential biomedical and bioelectronics applications.
MATERIALS TODAY BIO
(2021)
Review
Biochemistry & Molecular Biology
Traian Constantin, Mihai Pavalean, Stefana Bucur, Maria Magdalena Constantin, Alin Codrut Nicolescu, Irina Pacu, Victor Madan
Summary: Bladder cancer animal models can be categorized as either autochthonous or non-autochthonous, with the non-autochthonous models further classified into syngeneic and xenograft models. These models have different characteristics and applications based on the type of tumor implantation.
Article
Engineering, Multidisciplinary
Mariusz Ksiazek
Summary: The author explores the potential use of polymerized sulfur waste as a biocompatible material in biomaterial production, particularly in surgical applications. Experimental studies have demonstrated that polymerized sulfur waste shows promise as a biocomposite, opening up new possibilities for the industry.
COMPOSITES PART B-ENGINEERING
(2021)
Article
Biochemistry & Molecular Biology
Alana N. Vagnozzi, Jian-Guo Li, Jin Chiu, Roshanak Razmpour, Rebecca Warfield, Servio H. Ramirez, Domenico Pratico
Summary: VPS35 plays a crucial role in tau metabolism and neuropathology, with its overexpression reducing pathological tau in neuronal cells while genetic silencing leads to accumulation. The availability of active cathepsin D mediates the effect of VPS35 on pathological tau accumulation, making it a potential therapeutic target for human tauopathies.
MOLECULAR PSYCHIATRY
(2021)
Article
Behavioral Sciences
Etedal Ahmed A. Ibrahim, Ghada A. Mutaal Badri, Khabab Abbasher Hussien Mohamed Ahmed, Mohammed Eltahier Abdalla Omer
Summary: The study found that environmental conditions were the most common triggers of migraine headache among Sudanese patients, while Acetaminophen was the most commonly used drug for relieving migraine in this population. The majority of patients were female (80%), aged 26-35 years (56.9%), and a significant proportion were housewives (40%).
BRAIN AND BEHAVIOR
(2021)
Review
Humanities, Multidisciplinary
Ahmad Fekry Moussa, Ibrahim Suleiman Al Qatawneh, Moustafa Elmetwaly Kandeel
Summary: This study focuses on the procedural necessity of primary investigations in the Arab countries, particularly in Egypt. It analyzes the position of the Arab procedural legislation and judiciary systems regarding procedural necessity and argues against expanding discretionary powers that may lead to abuse of officials and restrict individual rights and freedoms.
HUMANITIES & SOCIAL SCIENCES COMMUNICATIONS
(2022)
Article
Environmental Sciences
Yin Lu, Qin Ma, Xiaolu Xu, Zhefu Yu, Tianjiao Guo, Yangkai Wu
Summary: The study showed that exposure to poly styrene microplastics (PS-MPs) can lead to increased apoptosis and cell death, higher micronucleus rate, and reduced mitotic index in V. faba root cells. Additionally, it causes significant oxidative stress by altering the expression of antioxidant enzymes and genes related to cell cycle and DNA repair.
ENVIRONMENTAL POLLUTION
(2021)
Article
Physics, Multidisciplinary
Gabriel Koch Ocker
Summary: This study presents a statistical field theory for networks of integrate-and-fire neurons with stochastic spike emission, revealing the impact of spike-driven reset of the membrane voltage on population activity. The study uncovers bistability and fluctuation effects in the mean-field dynamics, as well as the roles of spike resets and recurrent inhibition in stabilizing network activity. It also calculates the phase diagram for inhibitory stabilization and finds that wide regions of parameter space exhibit inhibition-stabilized regime.
Article
Engineering, Chemical
James Dufty, Jeffrey Wrighton, Kai Luo
Summary: This article considers definitions for local pressure in an inhomogeneous fluid, covering both equilibrium and local equilibrium states, and reconciles thermodynamic and mechanical (hydrodynamic) contexts. Remaining problems and uncertainties in the topic are also discussed.
Article
Multidisciplinary Sciences
Peter C. Chu
Summary: In ocean dynamics, two different treatments are found for horizontal pressure gradient force and gravity, with vertical component being much larger than horizontal in both cases. Horizontal pressure gradient force is considered dominant, while horizontal gravity is completely omitted in oceanography. The importance of horizontal gravity is identified using a non-dimensional C number, with global data showing an unexpectedly large C number around 24.
SCIENTIFIC REPORTS
(2021)
Article
Education & Educational Research
Olga Garanina, Nidal Al Said, Valery Stepenko, Marija Troyanskaya
Summary: The study developed and tested an original model illustrating personality development in the information society, finding that its implementation increased students' use of resources for personal growth. The model's practical value lies in its applicability to higher education systems in various countries, especially in the context of distance learning and social isolation caused by the COVID-19 pandemic.
EDUCATION AND INFORMATION TECHNOLOGIES
(2021)
Article
Agricultural Engineering
Jiangkuan Xing, Ryoichi Kurose, Kun Luo, Jianren Fan
Summary: Researchers have developed a new tool for establishing solid fuel conversion kinetics from thermogravimetric analysis (TGA) measurements using chemistry-informed machine learning approaches. The derived pyrolysis kinetics accurately reproduce the pyrolysis process for different biomass types and demonstrate advantages in predicting volatiles yield.
BIORESOURCE TECHNOLOGY
(2022)
Article
Chemistry, Physical
Sharmin Sultana, Malik Abdul Rub, Marzia Rahman, Shahed Rana, Mohammad Majibur Rahman, Md Anamul Hoque, Yousef G. Alghamdi, Abdullah M. Asiri
Summary: In this study, the aggregation behaviors of PVA and TTAB in alcohols/diols media were investigated using conductivity measurements. The physico-chemical parameters and thermodynamic properties were determined. The results showed that the CMC values varied in different solvents, indicating the significant influence of solvents on the micelle formation of TTAB + PVA mixture. It was also found that PVA molecules interacted exclusively with TTAB through hydrogen bonding, ion-dipole, and hydrophobic interactions.
JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY
(2023)
Article
Engineering, Chemical
Md. Anamul Hoque, Shamim Mahbub, Md. Tuhinur R. Joy, Malik Abdul Rub, Shahed Rana, Dileep Kumar, Yousef G. Alghamdi, Abdullah M. Asiri, Mohammed Abdullah Khan
Summary: The micellization behavior of CTAB and BSA mixture in different diols media was studied. The critical micelle concentration (cmc) values of the mixture decreased with increasing temperature and followed the order: cmc(1,5-PD)>cmc(1,2-PrD)>cmc(2,3-BD). The degree of micelle ionization (a) increased with carbon chain length and temperature. The thermodynamic parameters and the contribution of the solvent were also evaluated.
CHEMICAL ENGINEERING COMMUNICATIONS
(2023)
Article
Chemistry, Organic
Mohammad Asad, Muhammad Nadeem Arshad, Abdullah M. Asiri, Mohammed T. N. Musthafa, Salman A. Khan, Mohd Rehan, Mohammad Oves
Summary: A series of novel N-methylspiropyrrolidine hybrids were synthesized using 1,3-dipolar cycloaddition reaction, and their structures, antibacterial activity, and mechanism of action were investigated.
POLYCYCLIC AROMATIC COMPOUNDS
(2023)
Article
Chemistry, Physical
Naved Azum, Maha Moteb Alotaibi, Maroof Ali, Malik Abdul Rub, Hadi M. Marwani, Khalid A. Alamry, Abdullah M. Asiri
Summary: The current study investigated the influence of an ionic liquid and cationic surfactant on the physicochemical properties of an anaesthetic drug, tetracaine hydrochloride (TCH). Tensiometric and absorption spectroscopic methods were used to analyze the interaction between TCH and the ionic liquid (1-hexadecyl-3-methyl imidazolium chloride, SAIL) and cationic surfactant (cetylpyridinium chloride, CPC). The results showed that TCH exhibited a higher synergistic interaction with SAIL compared to CPC, which was confirmed by UV-visible spectroscopy and the binding constant value.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Review
Polymer Science
Guravtar Singh Mann, Naved Azum, Anish Khan, Malik Abdul Rub, Md Imtaiyaz Hassan, Kisa Fatima, Abdullah M. Asiri
Summary: Global climate change has already caused various environmental effects and led to a shift in focus towards sustainable materials. Green composites, which combine renewable fibers with polymers, offer a wide range of applications and superior features compared to conventional materials.
Article
Chemistry, Analytical
Sulaiman Y. Alfaifi, Waheed Abiodun Adeosun, Abdullah M. Asiri, Mohammed M. Rahman
Summary: This study proposed the use of doped Co3O4-ZnO nanorod materials for the detection of aspartic acid using differential pulse voltammetry. The synthesized composite exhibited excellent properties for the detection of aspartic acid, including low limit of detection, high sensitivity, and wide linear range. The developed sensor based on Co3O4-ZnO nanorod material showed repeatable and stable current response for aspartic acid, with no interference from other electroactive compounds.
Article
Polymer Science
Aftab Aslam Parwaz Khan, Mallikarjunagouda B. Patil, Laxmibai P. Rathod, Shivalila G. Vader, Pankaj Raizada, Pardeep Singh, Maha M. Alotaibi, Mohammad Omaish Ansari, Anish Khan, Naved Azum, Malik Abdul Rub, Muhammad Nadeem Arshad, Abdullah M. Asiri
Summary: The study assessed the potential of nanocomposite membranes (NCMs) made of sodium alginate and embedded with synthesized zeolitic imidazole framework-8 (ZIF-8) as fillers for separating gaseous mixtures generated by methane reforming. ZIF-8 crystals were synthesized through hydrothermal synthesis, with sizes ranging from 50 to 70 nm. NCMs with 15% filler loading (synthesized ZIF-8) outperformed neat polymer membranes in terms of H-2 permeability and selectivity, achieving a purity of up to 95%. However, NCMs did not perform better than neat polymer membranes in separating gas mixtures. The combination of ZIF-8 and sodium alginate as fillers is a new and worth investigating.
Article
Polymer Science
Esraa M. Bakhsh, Sher Bahadar Khan, Nujud Maslamani, Ekram Y. Danish, Kalsoom Akhtar, Abdullah M. Asiri
Summary: In this study, CMC/CuO-TiO2 beads were developed as a catalyst for the reduction of organic and inorganic contaminants. These beads demonstrated excellent catalytic activity and stability.
Article
Chemistry, Physical
Mohammad Asad, Muhammad Nadeem Arshad, Abdullah M. Asiri, Hadi M. Marwani, Khalid A. Alamry, Mohammad Mahboob Alam, Syed Nazreen, Ahmed A. Elhenawy, Mohammed M. Rahman
Summary: N-Acylated-2-pyrazolines (NA2Pyr) were synthesized using chalcone and hydrazine hydrate, and their structures were determined. A metal ion sensor for lead (Pb2+) was developed by combining a conducting coating binder (PEDOT:PSS) with a NA2Pyr modified electrode (NA2Pyr/GCE). The sensor exhibited high sensitivity and a wide linear dynamic range.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Biochemistry & Molecular Biology
Zunera Khalid, Syed Salman Shafqat, Hafiz Adnan Ahmad, Munawar Ali Munawar, Sadaf Mutahir, Safaa M. Elkholi, Syed Rizwan Shafqat, Rahila Huma, Abdullah Mohammed Asiri
Summary: Diabetes is a chronic metabolic disorder characterized by high blood sugar levels due to insulin deficiency or ineffective use. Alpha-glucosidase inhibitors are commonly used to control hyperglycemia, but can cause side effects. This study synthesized and tested a new series of compounds for their alpha-glucosidase inhibition potential. The compounds 14k and 14l showed strong inhibitory activity and in silico studies confirmed their interactions with the enzyme. This research provides potential candidates for the development of new antidiabetic drugs.
Article
Polymer Science
Khasan S. Karimov, Muhammad Tariq Saeed Chani, Noshin Fatima, Abdullah M. Asiri, Mohammed M. Rahman
Summary: Optimized surface-type impedimetric and capacitive proximity sensors have been fabricated on paper substrates using rubbing-in technology. These sensors can detect objects by sensing changes in impedance and/or capacitance when the object approaches, and they can be widely used in various fields due to their low cost, easy fabrication, and environmentally friendly materials.
Review
Chemistry, Multidisciplinary
Hafsah A. Klfout, Abdullah M. Asiri, Khalid A. Alamry, Mahmoud A. Hussein
Summary: Polybenzoxazine (PBz) is an excellent resin with diverse applications. The peculiar properties of benzoxazines have attracted the attention of researchers worldwide. However, petroleum-based benzoxazines are facing environmental concerns, leading to the research and development of bio-based alternatives. Bio-based polybenzoxazine, epoxy, and polysiloxane-based resins have gained interest in recent years due to their anticorrosion, eco-friendly, affordable, and low water absorption properties. This review provides an overview of polybenzoxazine, focusing on the advances in synthesizing bio-based polybenzoxazine, their properties, and their use in coating applications.
Article
Chemistry, Multidisciplinary
Mohammad Mahboob Alam, Serag Eldin I. Elbehairi, Ali A. Shati, Rania A. Hussien, Mohammad Y. Alfaifi, Azizah M. Malebari, Mohammad Asad, Ahmed A. Elhenawy, Abdullah M. Asiri, Ali M. Mahzari, Reem F. Alshehri, Syed Nazreen
Summary: Synthetic modification of eugenol, a natural anticancer agent, resulted in the production of new 1,3,4-oxadiazole analogues as inhibitors of thymidylate synthase. Compound 9 and 17 showed promising cytotoxicity against breast cancer and prostate cancer cells, without any side effects.
NEW JOURNAL OF CHEMISTRY
(2023)