Targeting the tumor microenvironment as a potential therapeutic approach in colorectal cancer: Rational and progress

Therapeutic Potential of Targeting Wnt/β-Catenin Pathway in Treatment of Colorectal Cancer: Rational and Progress

(2017) Afsane Bahrami et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

C-Met as a potential target for the treatment of gastrointestinal cancer: Current status and future perspectives

(2017) Afsane Bahrami et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Deciphering biological characteristics of tumorigenic subpopulations in human colorectal cancer reveals cellular plasticity

(2016) HamidReza Mirzaei et al.   Journal of Research in Medical Sciences

Low expression of chloride channel accessory 1 predicts a poor prognosis in colorectal cancer: The question is still open

(2015) Soodabeh ShahidSales et al.   CANCER

Early detection of colorectal cancer: from conventional methods to novel biomarkers

(2015) Nasimeh Vatandoost et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Stromal gene expression defines poor-prognosis subtypes in colorectal cancer

(2015) Alexandre Calon et al.   NATURE GENETICS

The consensus molecular subtypes of colorectal cancer

(2015) Justin Guinney et al.   NATURE MEDICINE

Targeting the TGFβ pathway for cancer therapy

(2015) Cindy Neuzillet et al.   PHARMACOLOGY & THERAPEUTICS

Neoantigens in cancer immunotherapy

(2015) T. N. Schumacher et al.   SCIENCE

Cancer-Associated Fibroblasts Connect Metastasis-Promoting Communication in Colorectal Cancer

(2015) Joke Tommelein et al.   Frontiers in Oncology

A 5-gene classifier from the carcinoma-associated fibroblast transcriptomic profile and clinical outcome in colorectal cancer

(2015) Mireia Berdiel-Acer et al.   Oncotarget

Classification of current anticancer immunotherapies

(2015) Lorenzo Galluzzi et al.   Oncotarget

Chromosomal Instability Is Associated with Higher Expression of Genes Implicated in Epithelial-Mesenchymal Transition, Cancer Invasiveness, and Metastasis and with Lower Expression of Genes Involved in Cell Cycle Checkpoints, DNA Repair, and Chromatin Maintenance

(2015) Anna V. Roschke et al.   NEOPLASIA

Evolution of the Cancer Stem Cell Model

(2014) Antonija Kreso et al.   Cell Stem Cell

Targeting c-MET/HGF Signaling Pathway in Upper Gastrointestinal Cancers: Rationale and Progress

(2014) Sharareh Gholamin et al.   CURRENT DRUG TARGETS

Hallmarks in colorectal cancer: Angiogenesis and cancer stem-like cells

(2014) Muriel Mathonnet   WORLD JOURNAL OF GASTROENTEROLOGY

Targeting Angiogenesis and Tumor Microenvironment in Metastatic Colorectal Cancer: Role of Aflibercept

(2014) Guido Giordano et al.   Gastroenterology Research and Practice

Mechanism of Action of Conventional and Targeted Anticancer Therapies: Reinstating Immunosurveillance

(2013) Laurence Zitvogel et al.   IMMUNITY

IL-2–dependent tuning of NK cell sensitivity for target cells is controlled by regulatory T cells

(2013) Georg Gasteiger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Towards the introduction of the ‘Immunoscore’ in the classification of malignant tumours

(2013) Jérôme Galon et al.   JOURNAL OF PATHOLOGY

Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions

(2013) Felipe De Sousa E Melo et al.   NATURE MEDICINE

Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation

(2012) Alexandre Calon et al.   CANCER CELL

Targeting Carcinoma-Associated Fibroblasts Within the Tumor Stroma With a Fibroblast Activation Protein-Activated Prodrug

(2012) W. N. Brennen et al.   JNCI-Journal of the National Cancer Institute

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Targeting the TGFβ signalling pathway in disease

(2012) Rosemary J. Akhurst et al.   NATURE REVIEWS DRUG DISCOVERY

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

Antiangiogenic therapy: impact on invasion, disease progression and metastasis

(2011) John M. L. Ebos et al.   Nature Reviews Clinical Oncology

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Hypoxia, angiogenesis and cancer therapy: To breathe or not to breathe?

(2010) Paolo Michieli   CELL CYCLE

Tumors as Organs: Complex Tissues that Interface with the Entire Organism

(2010) Mikala Egeblad et al.   DEVELOPMENTAL CELL

Disease Course Patterns After Discontinuation of Bevacizumab: Pooled Analysis of Randomized Phase III Trials

(2010) David Miles et al.   JOURNAL OF CLINICAL ONCOLOGY

Metronomic chemotherapy: new rationale for new directions

(2010) Eddy Pasquier et al.   Nature Reviews Clinical Oncology

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

Cancer associated fibroblasts (CAFs) in tumor microenvironment

(2009) Fei Xing   Frontiers in Bioscience-Landmark

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Matrix Metalloproteinases As Novel Biomarker s and Potential Therapeutic Targets in Human Cancer

(2009) Roopali Roy et al.   JOURNAL OF CLINICAL ONCOLOGY

JAK2 stimulates homologous recombination and genetic instability: potential implication in the heterogeneity of myeloproliferative disorders

(2008) I. Plo et al.   BLOOD

Coevolution in the tumor microenvironment

(2008) Robert A Weinberg   NATURE GENETICS

No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas

(2008) Wen Qiu et al.   NATURE GENETICS

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE

Adaptation to hypoxia and acidosis in carcinogenesis and tumor progression

(2008) Jennifer S. Fang et al.   SEMINARS IN CANCER BIOLOGY