Angiogenesis biomarkers and their targeting ligands as potential targets for tumor angiogenesis

PiggyBac as a novel vector in cancer gene therapy: current perspective

(2016) H Mirzaei et al.   CANCER GENE THERAPY

Mesenchymal stem cell: a new horizon in cancer gene therapy

(2016) M Mohammadi et al.   CANCER GENE THERAPY

Circulating microRNA-192 as a diagnostic biomarker in human chronic lymphocytic leukemia

(2016) S Fathullahzadeh et al.   CANCER GENE THERAPY

Circulating microRNA: a new candidate for diagnostic biomarker in neuroblastoma

(2016) M Mohammadi et al.   CANCER GENE THERAPY

Glioblastoma: exosome and microRNA as novel diagnosis biomarkers

(2016) L Saadatpour et al.   CANCER GENE THERAPY

Prospects for chimeric antigen receptor (CAR) γδ T cells: A potential game changer for adoptive T cell cancer immunotherapy

(2016) Hamid Reza Mirzaei et al.   CANCER LETTERS

Epi-Drugs and Epi-miRs: Moving Beyond Current Cancer Therapies

(2016) Reza Salarinia et al.   CURRENT CANCER DRUG TARGETS

Application of Mesenchymal Stem Cells in Melanoma: A Potential Therapeutic Strategy for Delivery of Targeted Agents

(2016) Hamed Mirzaei et al.   CURRENT MEDICINAL CHEMISTRY

Circulating microRNAs as Potential Diagnostic Biomarkers and Therapeutic Targets in Gastric Cancer: Current Status and Future Perspectives

(2016) Hamed Mirzaei et al.   CURRENT MEDICINAL CHEMISTRY

Circulating microRNAs in Hepatocellular Carcinoma: Potential Diagnostic and Prognostic Biomarkers

(2016) Hamid Mirzaei et al.   CURRENT PHARMACEUTICAL DESIGN

Boron neutron capture therapy: Moving toward targeted cancer therapy

(2016) Hamed Mirzaei et al.   Journal of Cancer Research and Therapeutics

SiRNA and epigenetic aberrations in ovarian cancer

(2016) HamidReza Mirzaei et al.   Journal of Cancer Research and Therapeutics

A phase I, first in human study of FP-1039 (GSK3052230), a novel FGF ligand trap, in patients with advanced solid tumors

(2015) A. W. Tolcher et al.   ANNALS OF ONCOLOGY

von Willebrand factor fibers promote cancer-associated platelet aggregation in malignant melanoma of mice and humans

(2015) A. T. Bauer et al.   BLOOD

Gastric cancer-associated enhancement of von Willebrand factor is regulated by vascular endothelial growth factor and related to disease severity

(2015) Xia Yang et al.   BMC CANCER

Nintedanib plus docetaxel as second-line therapy in patients with non-small-cell lung cancer: a network meta-analysis

(2015) Sanjay Popat et al.   Future Oncology

Second-line dovitinib (TKI258) in patients with FGFR2-mutated or FGFR2-non-mutated advanced or metastatic endometrial cancer: a non-randomised, open-label, two-group, two-stage, phase 2 study

(2015) Gottfried E Konecny et al.   LANCET ONCOLOGY

Targeting Angiogenesis in Cancer Therapy: Moving Beyond Vascular Endothelial Growth Factor

(2015) Y. Zhao et al.   ONCOLOGIST

PDGFRβ signalling regulates local inflammation and synergizes with hypercholesterolaemia to promote atherosclerosis

(2015) Chaoyong He et al.   Nature Communications

Powerful anti-tumor and anti-angiogenic activity of a new anti-vascular endothelial growth factor receptor 1 peptide in colorectal cancer models

(2015) Valeria Cicatiello et al.   Oncotarget

Focal adhesion kinase-dependent focal adhesion recruitment of SH2 domains directs SRC into focal adhesions to regulate cell adhesion and migration

(2015) Jui-Chung Wu et al.   Scientific Reports

Role of Platelet-Derived Growth Factor/Platelet-Derived Growth Factor Receptor Axis in the Trafficking of Circulating Fibrocytes in Pulmonary Fibrosis

(2014) Yoshinori Aono et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Selection of DNA aptamers against epidermal growth factor receptor with high affinity and specificity

(2014) Deng-Liang Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A review of ELTD1, a pro-angiogenic adhesion GPCR

(2014) David M. Favara et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Vascular RhoJ Is an Effective and Selective Target for Tumor Angiogenesis and Vascular Disruption

(2014) Chan Kim et al.   CANCER CELL

Phase I study of olaratumab in Japanese patients with advanced solid tumors

(2014) Toshihiko Doi et al.   CANCER SCIENCE

MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-Ras

(2014) Zhumei Shi et al.   NEURO-ONCOLOGY

Cell Surface Nucleolin as a Target for Anti-Cancer Therapies

(2014) Marina Koutsioumpa et al.   Recent Patents on Anti-Cancer Drug Discovery

MicroRNAs: Promising New Antiangiogenic Targets in Cancer

(2014) Sandra Gallach et al.   Biomed Research International

Overexpression of nucleolin and different expression sites both related to the prognosis of gastric cancer

(2013) Wensheng Qiu et al.   APMIS

CGKRK-modified nanoparticles for dual-targeting drug delivery to tumor cells and angiogenic blood vessels

(2013) Quanyin Hu et al.   BIOMATERIALS

A Core Human Primary Tumor Angiogenesis Signature Identifies the Endothelial Orphan Receptor ELTD1 as a Key Regulator of Angiogenesis

(2013) Massimo Masiero et al.   CANCER CELL

Targeting the PDGF signaling pathway in tumor treatment

(2013) Carl-Henrik Heldin   Cell Communication and Signaling

Critical Appraisal of Ramucirumab (IMC-1121B) for Cancer Treatment: From Benchside to Clinical Use

(2013) Giuseppe Aprile et al.   DRUGS

A randomised phase II study of TSU-68 in patients with hepatocellular carcinoma treated by transarterial chemoembolisation

(2013) Yoshitaka Inaba et al.   EUROPEAN JOURNAL OF CANCER

Proapoptotic Peptide-Mediated Cancer Therapy Targeted to Cell Surface p32

(2013) Lilach Agemy et al.   MOLECULAR THERAPY

Human antibodies targeting the C-type lectin-like domain of the tumor endothelial cell marker clec14a regulate angiogenic properties in vitro

(2013) M K Ki et al.   ONCOGENE

Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cancer

(2013) W Kong et al.   ONCOGENE

miRNAs as Modulators of Angiogenesis

(2013) S. Landskroner-Eiger et al.   Cold Spring Harbor Perspectives in Medicine

PlGF: A Multitasking Cytokine with Disease-Restricted Activity

(2013) M. Dewerchin et al.   Cold Spring Harbor Perspectives in Medicine

TEM8/ANTXR1 Blockade Inhibits Pathological Angiogenesis and Potentiates Tumoricidal Responses against Multiple Cancer Types

(2012) Amit Chaudhary et al.   CANCER CELL

Integrin α2β1Mediates Tyrosine Phosphorylation of Vascular Endothelial Cadherin Induced by Invasive Breast Cancer Cells

(2012) Mehran Haidari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Safety, Pharmacokinetic, and Pharmacodynamic Phase I Dose-Escalation Trial of PF-00562271, an Inhibitor of Focal Adhesion Kinase, in Advanced Solid Tumors

(2012) Jeffrey R. Infante et al.   JOURNAL OF CLINICAL ONCOLOGY

Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization

(2012) Lothar C Dieterich et al.   JOURNAL OF PATHOLOGY

Peptide-Based Targeting of the Platelet-Derived Growth Factor Receptor Beta

(2012) Vasileios Askoxylakis et al.   MOLECULAR IMAGING AND BIOLOGY

The role of RhoJ in endothelial cell biology and angiogenesis

(2011) Katarzyna Leszczynska et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Targeting surface nucleolin with multivalent HB-19 and related Nucant pseudopeptides results in distinct inhibitory mechanisms depending on the malignant tumor cell type

(2011) Bernard Krust et al.   BMC CANCER

The synthetic peptide P111-136 derived from the C-terminal domain of heparin affin regulatory peptide inhibits tumour growth of prostate cancer PC-3 cells

(2011) Yamina Hamma-Kourbali et al.   BMC CANCER

A Simple Approach to Cancer Therapy Afforded by Multivalent Pseudopeptides That Target Cell-Surface Nucleoproteins

(2011) D. Destouches et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice

(2011) Yoko Fukushima et al.   JOURNAL OF CLINICAL INVESTIGATION

PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells

(2011) Yuan Xue et al.   NATURE MEDICINE

Identification of nucleolin as a cellular receptor for human respiratory syncytial virus

(2011) Farnoosh Tayyari et al.   NATURE MEDICINE

Identification and angiogenic role of the novel tumor endothelial marker CLEC14A

(2011) M Mura et al.   ONCOGENE

Specific penetration and accumulation of a homing peptide within atherosclerotic plaques of apolipoprotein E-deficient mice

(2011) J. Hamzah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endoglin is a novel endothelial cell specification gene

(2011) Saswati Banerjee et al.   Stem Cell Research

Inhibition of Prostate Cancer Using RNA Interference-directed Knockdown of Platelet-derived Growth Factor Receptor

(2011) Yong Hyun Park et al.   UROLOGY

Ramucirumab (IMC-1121B): Monoclonal Antibody Inhibition of Vascular Endothelial Growth Factor Receptor-2

(2011) Jennifer Spratlin   Current Oncology Reports

RhoJ/TCL Regulates Endothelial Motility and Tube Formation and Modulates Actomyosin Contractility and Focal Adhesion Numbers

(2010) Sukhbir Kaur et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Clec14a is specifically expressed in endothelial cells and mediates cell to cell adhesion

(2010) Seung-Sik Rho et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Suppression of tumorigenicity of rhabdoid tumor derived G401 cells by the multivalent HB-19 pseudopeptide that targets surface nucleolin

(2010) Bernard Krust et al.   BIOCHIMIE

Targeting surface nucleolin with a multivalent pseudopeptide delays development of spontaneous melanoma in RET transgenic mice

(2010) Diala El Khoury et al.   BMC CANCER

PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments

(2010) Isabelle Tanjoni et al.   CANCER BIOLOGY & THERAPY

Dynamics of endothelial cell behavior in sprouting angiogenesis

(2010) Hanna M Eilken et al.   CURRENT OPINION IN CELL BIOLOGY

Mitochondrial p32 Protein Is a Critical Regulator of Tumor Metabolism via Maintenance of Oxidative Phosphorylation

(2010) V. Fogal et al.   MOLECULAR AND CELLULAR BIOLOGY

Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting

(2010) Lars Jakobsson et al.   NATURE CELL BIOLOGY

Platelet-derived growth factor mediates survival of leukemic large granular lymphocytes via an autocrine regulatory pathway

(2009) J. Yang et al.   BLOOD

Host-Derived Tumor Endothelial Marker 8 Promotes the Growth of Melanoma

(2009) M. Cullen et al.   CANCER RESEARCH

Targeting cancer vasculature via endoglin/CD105: a novel antibody-based diagnostic and therapeutic strategy in solid tumours

(2009) E. Fonsatti et al.   CARDIOVASCULAR RESEARCH

Nrarp Coordinates Endothelial Notch and Wnt Signaling to Control Vessel Density in Angiogenesis

(2009) Li-Kun Phng et al.   DEVELOPMENTAL CELL

PDGF-C and -D and their receptors PDGFR-α and PDGFR-β in atherosclerotic human arteries

(2009) H. Karvinen et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer

(2009) Paula J. Bates et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Anti-endoglin monoclonal antibodies are effective for suppressing metastasis and the primary tumors by targeting tumor vasculature

(2009) Shima Uneda et al.   INTERNATIONAL JOURNAL OF CANCER

Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice

(2009) Jing Qing et al.   JOURNAL OF CLINICAL INVESTIGATION

A role for a novel protein, nucleolin, in Parkinson's disease

(2009) W. Michael Caudle et al.   NEUROSCIENCE LETTERS

Nuclear translocation of urokinase-type plasminogen activator

(2008) V. Stepanova et al.   BLOOD

A novel method of differential gene expression analysis using multiple cDNA libraries applied to the identification of tumour endothelial genes

(2008) John MJ Herbert et al.   BMC GENOMICS

Mitochondrial/Cell-Surface Protein p32/gC1qR as a Molecular Target in Tumor Cells and Tumor Stroma

(2008) V. Fogal et al.   CANCER RESEARCH

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

(2008) Victoria Sanz-Moreno et al.   CELL

Wnt/β-Catenin and Fgf Signaling Control Collective Cell Migration by Restricting Chemokine Receptor Expression

(2008) Andy Aman et al.   DEVELOPMENTAL CELL

Differential roles of PDGFR-α and PDGFR-β in angiogenesis and vessel stability

(2008) Junhang Zhang et al.   FASEB JOURNAL

Anti-tumor activity of an anti-endoglin monoclonal antibody is enhanced in immunocompetent mice

(2008) Masanori Tsujie et al.   INTERNATIONAL JOURNAL OF CANCER

Modulation of Angiogenesis by a Tetrameric Tripeptide That Antagonizes Vascular Endothelial Growth Factor Receptor 1

(2008) Salvatore Ponticelli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK

(2008) Sara M. Weis et al.   JOURNAL OF CELL BIOLOGY

The FGF system has a key role in regulating vascular integrity

(2008) Masahiro Murakami et al.   JOURNAL OF CLINICAL INVESTIGATION

The cancer biomarker problem

(2008) Charles L. Sawyers   NATURE

Mammalian Rho GTPases: new insights into their functions from in vivo studies

(2008) Sarah J. Heasman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The α-receptor for platelet-derived growth factor as a target for antibody-mediated inhibition of skeletal metastases from prostate cancer cells

(2008) M R Russell et al.   ONCOGENE

PDGFR-A is a therapeutic target in alveolar rhabdomyosarcoma

(2008) E Taniguchi et al.   ONCOGENE

Suppression of Tumor Growth and Angiogenesis by a Specific Antagonist of the Cell-Surface Expressed Nucleolin

(2008) Damien Destouches et al.   PLoS One