Tetrandrine, an agonist of aryl hydrocarbon receptor, reciprocally modulates the activities of STAT3 and STAT5 to suppress Th17 cell differentiation

Tetrandrine ameliorates collagen-induced arthritis in mice by restoring the balance between Th17 and Treg cells via the aryl hydrocarbon receptor

(2016) Xusheng Yuan et al.   BIOCHEMICAL PHARMACOLOGY

Tetrandrine suppresses human glioma growth by inhibiting cell survival, proliferation and tumour angiogenesis through attenuating STAT3 phosphorylation

(2015) Ji-wei Ma et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ghrelin Inhibits the Differentiation of T Helper 17 Cells through mTOR/STAT3 Signaling Pathway

(2015) Yanhui Xu et al.   PLoS One

Novel role of hnRNP-A2/B1 in modulating aryl hydrocarbon receptor ligand sensitivity

(2014) See-Wun Cho et al.   ARCHIVES OF TOXICOLOGY

STAT5 programs a distinct subset of GM-CSF-producing T helper cells that is essential for autoimmune neuroinflammation

(2014) Wanqiang Sheng et al.   CELL RESEARCH

Decreased expression of microRNA-21 correlates with the imbalance of Th17 and Treg cells in patients with rheumatoid arthritis

(2014) Liyang Dong et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

JAK2-STAT3 Blockade by AG490 Suppresses Autoimmune Arthritis in Mice via Reciprocal Regulation of Regulatory T Cells and Th17 Cells

(2014) J.-S. Park et al.   JOURNAL OF IMMUNOLOGY

Red Ginseng Extract Ameliorates Autoimmune Arthritis via Regulation of STAT3 Pathway, Th17/Treg Balance, and Osteoclastogenesis in Mice and Human

(2014) JooYeon Jhun et al.   MEDIATORS OF INFLAMMATION

EGCG Attenuates Autoimmune Arthritis by Inhibition of STAT3 and HIF-1α with Th17/Treg Control

(2014) Eun-Ji Yang et al.   PLoS One

IL-21 induces IL-22 production in CD4+ T cells

(2014) Ada Yeste et al.   Nature Communications

Biology and function of the aryl hydrocarbon receptor: report of an international and interdisciplinary conference

(2012) Charlotte Esser   ARCHIVES OF TOXICOLOGY

STAT3 Transcription Factor Promotes Instability of nTreg Cells and Limits Generation of iTreg Cells during Acute Murine Graft-versus-Host Disease

(2012) Arian Laurence et al.   IMMUNITY

Interleukin-2/anti-interleukin-2 monoclonal antibody immune complex suppresses collagen-induced arthritis in mice by fortifying interleukin-2/STAT5 signalling pathways

(2012) Seon-Yeong Lee et al.   IMMUNOLOGY

The Aryl Hydrocarbon Receptor

(2012) Michael Van Voorhis et al.   TRANSPLANTATION

Aryl Hydrocarbon Receptor-Mediated Perturbations in Gene Expression during Early Stages of CD4+ T-cell Differentiation

(2012) Diana Rohlman et al.   Frontiers in Immunology

Suppressors of Cytokine Signaling (SOCS) Proteins and JAK/STAT Pathways

(2011) Taiga Tamiya et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Stat3 Phosphorylation Mediates Resistance of Primary Human T Cells to Regulatory T Cell Suppression

(2011) W. A. Goodman et al.   JOURNAL OF IMMUNOLOGY

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

(2011) Xiang-Ping Yang et al.   NATURE IMMUNOLOGY

IL-22-producing CD4+ T cells: Middle-men between the immune system and its environment

(2010) Sara Trifari et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Activation of the aryl hydrocarbon receptor reveals distinct requirements for IL-22 and IL-17 production by human T helper cells

(2010) Jean-Marie Ramirez et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

STAT3 in CD4+ T helper cell differentiation and inflammatory diseases

(2009) Charles E. Egwuagu   CYTOKINE

The aryl hydrocarbon receptor in immunity

(2009) Charlotte Esser et al.   TRENDS IN IMMUNOLOGY

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

The aryl hydrocarbon receptor: a regulator of Th17 and Treg cell development in disease

(2008) Peggy P Ho et al.   CELL RESEARCH

Discovery of Chromone-Based Inhibitors of the Transcription Factor STAT5

(2008) Judith Müller et al.   CHEMBIOCHEM

STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and CD4+CD25− effector T cells

(2008) Laura Passerini et al.   INTERNATIONAL IMMUNOLOGY

Effect of CVT-E002™ (COLD-fX®) versus a ginsenoside extract on systemic and gut-associated immune function

(2008) Patricia D. Biondo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

(2008) Marc Veldhoen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

(2008) Francisco J. Quintana et al.   NATURE

Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells

(2008) A. Kimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New insights into the roles of Stat5a/b and Stat3 in T cell development and differentiation

(2008) Lai Wei et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY