Salidroside attenuates neuroinflammation and improves functional recovery after spinal cord injury through microglia polarization regulation

IL-4 drives microglia and macrophages toward a phenotype conducive for tissue repair and functional recovery after spinal cord injury

(2016) Isaac Francos-Quijorna et al.   GLIA

Microglial polarization dynamics in dorsal spinal cord in the early stages following chronic sciatic nerve damage

(2016) Fangting Xu et al.   NEUROSCIENCE LETTERS

Lifetime Prevalence of Chronic Health Conditions Among Persons With Spinal Cord Injury

(2015) Lee L. Saunders et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

Lipopolysaccharides may aggravate apoptosis through accumulation of autophagosomes in alveolar macrophages of human silicosis

(2015) Shi Chen et al.   Autophagy

Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization

(2015) Kun Liu et al.   Autophagy

Adoptive transfer of M2 macrophages promotes locomotor recovery in adult rats after spinal cord injury

(2015) Shan-Feng Ma et al.   BRAIN BEHAVIOR AND IMMUNITY

The Effect of Autophagy on Inflammation Cytokines in Renal Ischemia/Reperfusion Injury

(2015) Haibin Ling et al.   INFLAMMATION

RBM5 and p53 expression after rat spinal cord injury: Implications for neuronal apoptosis

(2015) Jinlong Zhang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Azithromycin drives alternative macrophage activation and improves recovery and tissue sparing in contusion spinal cord injury

(2015) Bei Zhang et al.   Journal of Neuroinflammation

Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway

(2015) Xiaodi Fan et al.   Journal of Translational Medicine

Sestrin2 Protects Dopaminergic Cells against Rotenone Toxicity through AMPK-Dependent Autophagy Activation

(2015) Yi-Sheng Hou et al.   MOLECULAR AND CELLULAR BIOLOGY

Rapamycin increases neuronal survival, reduces inflammation and astrocyte proliferation after spinal cord injury

(2015) Yona Goldshmit et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Exendin-4 Enhances Motor Function Recovery via Promotion of Autophagy and Inhibition of Neuronal Apoptosis After Spinal Cord Injury in Rats

(2015) Hao-Tian Li et al.   MOLECULAR NEUROBIOLOGY

Icariin Promotes Angiogenic Differentiation and Prevents Oxidative Stress-Induced Autophagy in Endothelial Progenitor Cells

(2015) Yubo Tang et al.   STEM CELLS

Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death

(2015) S Liu et al.   Cell Death & Disease

Stimulation of autophagy promotes functional recovery in diabetic rats with spinal cord injury

(2015) Kai-liang Zhou et al.   Scientific Reports

Autophagy-mediated regulation of macrophages and its applications for cancer

(2014) Peiwen Chen et al.   Autophagy

Repurposing of Metformin and Aspirin by Targeting AMPK-mTOR and Inflammation for Pancreatic Cancer Prevention and Treatment

(2014) W. Yue et al.   Cancer Prevention Research

The Responses of Autophagy and Apoptosis to Oxidative Stress in Nucleus Pulposus Cells: Implications for Disc Degeneration

(2014) Jiang-Wei Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Targeting Microglial Activation in Stroke Therapy: Pharmacological Tools and Gender Effects

(2014) Y. Chen et al.   CURRENT MEDICINAL CHEMISTRY

Immune modulatory therapies for spinal cord injury – Past, present and future

(2014) Jason R. Plemel et al.   EXPERIMENTAL NEUROLOGY

SCM-198 inhibits microglial overactivation and attenuates Aβ1-40-induced cognitive impairments in rats via JNK and NF-кB pathways

(2014) Zhen-Yi Hong et al.   Journal of Neuroinflammation

Modulating Inflammatory Cell Responses to Spinal Cord Injury: All in Good Time

(2014) Amy L. Bowes et al.   JOURNAL OF NEUROTRAUMA

Pre-treatment with metformin activates Nrf2 antioxidant pathways and inhibits inflammatory responses through induction of AMPK after transient global cerebral ischemia

(2014) Ghorbangol Ashabi et al.   METABOLIC BRAIN DISEASE

Cathepsin S-mediated autophagic flux in tumor-associated macrophages accelerate tumor development by promoting M2 polarization

(2014) Min Yang et al.   Molecular Cancer

TNF and Increased Intracellular Iron Alter Macrophage Polarization to a Detrimental M1 Phenotype in the Injured Spinal Cord

(2014) Antje Kroner et al.   NEURON

Sulforaphane-induced autophagy flux prevents prion protein-mediated neurotoxicity through AMPK pathway

(2014) J.-H. Lee et al.   NEUROSCIENCE

TSC1 controls macrophage polarization to prevent inflammatory disease

(2014) Linnan Zhu et al.   Nature Communications

Cell death in intervertebral disc degeneration

(2013) Fan Ding et al.   APOPTOSIS

Upregulated autophagy protects cardiomyocytes from oxidative stress-induced toxicity

(2013) Debapriya Dutta et al.   Autophagy

Recruitment of Beneficial M2 Macrophages to Injured Spinal Cord Is Orchestrated by Remote Brain Choroid Plexus

(2013) Ravid Shechter et al.   IMMUNITY

The dual role of autophagy in chondrocyte responses in the pathogenesis of articular cartilage degeneration in osteoarthritis

(2013) JUN CHANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Reactive oxygen species-mediated mitochondrial dysfunction plays a critical role in high glucose-induced nucleus pulposus cell injury

(2013) Lianjun Yang et al.   INTERNATIONAL ORTHOPAEDICS

Inhibitory Effects of Salidroside on Nitric Oxide and Prostaglandin E2 Production in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages

(2013) Bocui Song et al.   JOURNAL OF MEDICINAL FOOD

The Protective Effect of Salvianolic Acid B on Blood–Spinal Cord Barrier After Compression Spinal Cord Injury in Rats

(2013) Zhong-kai Fan et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Temporal changes in monocyte and macrophage subsets and microglial macrophages following spinal cord injury in the lys-egfp-ki mouse model

(2013) Sakina G. Thawer et al.   JOURNAL OF NEUROIMMUNOLOGY

Autophagy Reduces Neuronal Damage and Promotes Locomotor Recovery via Inhibition of Apoptosis After Spinal Cord Injury in Rats

(2013) Peifu Tang et al.   MOLECULAR NEUROBIOLOGY

The TSC-mTOR pathway regulates macrophage polarization

(2013) Vanessa Byles et al.   Nature Communications

Managing Inflammation after Spinal Cord Injury through Manipulation of Macrophage Function

(2013) Yi Ren et al.   NEURAL PLASTICITY

The role of mTOR signaling pathway in spinal cord injury

(2012) Haruo Kanno et al.   CELL CYCLE

Mechanisms and regulation of autophagosome formation

(2012) Claudine Kraft et al.   CURRENT OPINION IN CELL BIOLOGY

Salidroside and tyrosol from Rhodiola protect H9c2 cells from ischemia/reperfusion-induced apoptosis

(2012) Liwei Sun et al.   LIFE SCIENCES

Protective Effects of a Rhodiola Crenulata Extract and Salidroside on Hippocampal Neurogenesis against Streptozotocin-Induced Neural Injury in the Rat

(2012) Ze-qiang Qu et al.   PLoS One

Adoptive transfer of Th1-conditioned lymphocytes promotes axonal remodeling and functional recovery after spinal cord injury

(2012) H Ishii et al.   Cell Death & Disease

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

Matter of Life and Death: the Pharmacological Approaches Targeting Apoptosis in Brain Diseases

(2011) Virve Cavallucci et al.   CURRENT PHARMACEUTICAL DESIGN

Repertoire of microglial and macrophage responses after spinal cord injury

(2011) Samuel David et al.   NATURE REVIEWS NEUROSCIENCE

A phase II trial of huperzine A in mild to moderate Alzheimer disease

(2011) M. S. Rafii et al.   NEUROLOGY

Emerging Concepts in Myeloid Cell Biology after Spinal Cord Injury

(2011) Alicia L. Hawthorne et al.   Neurotherapeutics

Antioxidant Therapies for Acute Spinal Cord Injury

(2011) Edward D. Hall   Neurotherapeutics

Altered M1/M2 activation patterns of monocytes in severe relapsing experimental rat model of multiple sclerosis. Amelioration of clinical status by M2 activated monocyte administration

(2010) Joanna Mikita et al.   Multiple Sclerosis Journal

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

Grafted Human Embryonic Progenitors Expressing Neurogenin-2 Stimulate Axonal Sprouting and Improve Motor Recovery after Severe Spinal Cord Injury

(2010) Florence E. Perrin et al.   PLoS One

The role of autophagy in spinal cord injury

(2009) Haruo Kanno et al.   Autophagy

Antiarrhythmic Activity of Phytoadaptogens in Short-Term Ischemia-Reperfusion of the Heart and Postinfarction Cardiosclerosis

(2009) L. N. Maslov et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Reactive Oxygen Species-Induced Stimulation of 5'AMP-Activated Protein Kinase Mediates Sevoflurane-Induced Cardioprotection

(2009) R. R. Lamberts et al.   CIRCULATION

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Inflammation, microglia, and alzheimer's disease

(2009) Brent Cameron et al.   NEUROBIOLOGY OF DISEASE

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE