Impaired erythropoietin synthesis in chronic kidney disease is caused by alterations in extracellular matrix composition

Physiology of the Renal Interstitium

(2015) M. Zeisberg et al.   Clinical Journal of the American Society of Nephrology

Erythropoietin Synthesis in Renal Myofibroblasts Is Restored by Activation of Hypoxia Signaling

(2015) T. Souma et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease

(2015) M Teresa Grande et al.   NATURE MEDICINE

Plasticity of Renal Erythropoietin-Producing Cells Governs Fibrosis

(2013) T. Souma et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Heterozygous disruption of activin receptor–like kinase 1 is associated with increased renal fibrosis in a mouse model of obstructive nephropathy

(2013) José M. Muñoz-Félix et al.   KIDNEY INTERNATIONAL

Renal Tubular HIF-2α Expression Requires VHL Inactivation and Causes Fibrosis and Cysts

(2012) Ruth E. Schietke et al.   PLoS One

Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice

(2011) Nariaki Asada et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia

(2010) P. P. Kapitsinou et al.   BLOOD

Mechanisms of Tubulointerstitial Fibrosis

(2010) M. Zeisberg et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Functional evidence confirmed by histological localization: overlapping expression of erythropoietin and HIF-2α in interstitial fibroblasts of the renal cortex

(2010) Hayo Castrop et al.   KIDNEY INTERNATIONAL

Common pathophysiological mechanisms of chronic kidney disease: Therapeutic perspectives

(2010) José M. López-Novoa et al.   PHARMACOLOGY & THERAPEUTICS

 v 3/ v 5 Integrins-FAK-RhoB: A Novel Pathway for Hypoxia Regulation in Glioblastoma

(2009) N. Skuli et al.   CANCER RESEARCH

Inflammation and EMT: an alliance towards organ fibrosis and cancer progression

(2009) Jose Miguel López-Novoa et al.   EMBO Molecular Medicine

Hypoxia-inducible factor-2α-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization

(2009) Alexander Paliege et al.   KIDNEY INTERNATIONAL

αvβ3 and αvβ5 integrins control glioma cell response to ionising radiation through ILK and RhoB

(2008) Sylvie Monferran et al.   INTERNATIONAL JOURNAL OF CANCER