Ragulator—a multifaceted regulator of lysosomal signaling and trafficking

A Ragulator–BORC interaction controls lysosome positioning in response to amino acid availability

(2017) Jing Pu et al.   JOURNAL OF CELL BIOLOGY

LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning

(2017) Przemyslaw A. Filipek et al.   JOURNAL OF CELL BIOLOGY

Crystal structure of the human lysosomal mTORC1 scaffold complex and its impact on signaling

(2017) Mariana E. G. de Araujo et al.   SCIENCE

Lysosomes in cancer—living on the edge (of the cell)

(2016) Saara Hämälistö et al.   CURRENT OPINION IN CELL BIOLOGY

BORC, a Multisubunit Complex that Regulates Lysosome Positioning

(2015) Jing Pu et al.   DEVELOPMENTAL CELL

Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1

(2015) S. Wang et al.   SCIENCE

Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1

(2015) Lawrence D. Schweitzer et al.   Cell Reports

The Lysosomal v-ATPase-Ragulator Complex Is a Common Activator for AMPK and mTORC1, Acting as a Switch between Catabolism and Anabolism

(2014) Chen-Song Zhang et al.   Cell Metabolism

Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1

(2012) Liron Bar-Peled et al.   CELL

ErbB2-Driven Breast Cancer Cell Invasion Depends on a Complex Signaling Network Activating Myeloid Zinc Finger-1-Dependent Cathepsin B Expression

(2012) Bo Rafn et al.   MOLECULAR CELL

Lysosomal positioning coordinates cellular nutrient responses

(2011) Viktor I. Korolchuk et al.   NATURE CELL BIOLOGY