Article
Ophthalmology
Jack S. Parker, Philip W. Dockery, Soosan Jacob, John S. Parker
Summary: CAIRS are semicircular pieces of donor corneal stroma that can be surgically implanted to flatten keratoconic corneas. Thinning CAIRS temporarily allows for easier insertion and the use of thicker segments for maximal flattening effect.
JOURNAL OF CATARACT AND REFRACTIVE SURGERY
(2021)
Article
Medicine, General & Internal
Nahia Goni, Itziar Martinez-Soroa, Oliver Ibarrondo, Mikel Azkargorta, Felix Elortza, David J. Galarreta, Arantxa Acera
Summary: This study analyzed tear proteome profiles before and after treatments in patients with Keratoconus to identify biomarkers altered by surgery. The results revealed dysregulated proteins in KC patients, with cytoskeleton-related processes being the most affected when comparing different treatment groups.
FRONTIERS IN MEDICINE
(2022)
Article
Ophthalmology
Jorge Vasco Costa, Tiago Monteiro, Nuno Franqueira, Fernando Faria-Correia, Jose Alfonso, Fernando Vaz
Summary: The study evaluated the long-term effectiveness, safety, and stability of Ferrara-type ICRS implantation by manual surgery in patients with keratoconus. The surgery significantly improved visual acuity, refractive error, and topographic values, and the improvement remained stable throughout a 5-year follow-up period. The procedure was deemed stable regardless of the patient's age, showing no regression in any visual or topographic parameter over time.
JOURNAL OF CATARACT AND REFRACTIVE SURGERY
(2021)
Article
Ophthalmology
Pablo Felipe Rodrigues, Bernardo Kaplan Moscovici, Guilherme Ferrara, Luciano Lamazales, Marcela Mara Silva Freitas, Leonardo Torquetti, Renato Ambrosio, Jose Alvaro Pereira Gomes
Summary: This study evaluated central corneal densitometry changes following Ferrara corneal ring segment implantation in keratoconus patients, finding a correlation between corneal densitometry and keratometry.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Ophthalmology
Indra Prasad Sharma, Ramendra Bakshi, Monica Chaudhry
Summary: This study aimed to compare the outcomes of keratoconic eyes treated with collagen cross-linking alone versus combined with intrastromal corneal ring segment. Results showed that the combined procedure resulted in better visual and refractive outcomes, with no serious complications noted during the study period.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Medicine, General & Internal
Abdelmajid Benlarbi, Sofiene Kallel, Clementine David, Raphael Barugel, Quentin Hays, Isabelle Goemaere, Roxane Cuyaubere, Marie Borderie, Vincent Borderie, Nacim Bouheraoua
Summary: The purpose of this study was to investigate the effects of intracorneal ring segments (ICRSs) on visual outcomes and epithelial remodeling in patients with duck-type keratoconus. The results showed that ICRS implantation significantly improved corrected and uncorrected distance visual acuity, and induced epithelial thickening along the segment. The study concluded that ICRS implantation can effectively manage duck-type keratoconus.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Ophthalmology
Carmen Bouza-Miguens, Felix Gonzalez-Lopez, Gema Alvarez, Rosa Godia, Jorge Gutierrez
Summary: Keratoconus can manifest asymmetrically and be difficult to solve. This study proposes a therapeutic approach involving the parallel implantation of a second ICRS to improve refractive status. The case report shows successful outcomes in improving refractive symmetry and optimizing vision in a patient with bilateral advanced keratoconus.
OPTOMETRY AND VISION SCIENCE
(2021)
Article
Ophthalmology
Mehrdad Mohammadpour, Mohsen Heirani, Narges Khoshtinat, Masoud Khorrami-Nejad
Summary: This study compared the five-year outcomes of two complete intracorneal implants (MyoRing and annular-shaped intracorneal implant [AICI]) combined with accelerated corneal cross-linking (A-CXL) in progressive keratoconus (KCN). The results showed that both AICI plus A-CXL and MyoRing plus A-CXL groups had similar pre- and postoperative visual, refractive, tomographic, biomechanical, and aberrometric parameters. After five years, MyoRing plus A-CXL group had significant improvements in anterior corneal surface (ACS) flat-K and corneal thickness, while AICI plus A-CXL group had significant improvements in ACS K-max and mean-K values. Both groups showed significant improvements in ACS steep-K and corneal astigmatism. Additionally, the AICI group had significantly better high order aberration compared to the MyoRing group. In conclusion, both MyoRing and AICI combined with A-CXL can significantly improve visual, refractive, and corneal aberrometric, biomechanical, and tomographic parameters and effectively halt the progression of KCN with comparable long-term outcomes.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Francesco D'Oria, Jorge L. Alio, Antonio Martinez-Abad, Luis Izquierdo Jr, Pablo Larco Jr, Ahmed A. Abdelghany
Summary: The purpose of this study was to evaluate the effects of intrastromal corneal ring segments (ICRS) that were explanted due to late extrusion on keratoconic corneas. The results showed that after explantation, the corneal topographic findings nearly returned to the baseline level, but there was a significant worsening in refractive cylinder. The main factors before implantation included keratoconus grade, keratometric readings, and visual acuities, while the main factors after ICRS implantation were refractive cylinder, corrected distance visual acuity, and uncorrected distance visual acuity. Corneal aberrations played an important role in the pre-explantation analysis.
JOURNAL OF CATARACT AND REFRACTIVE SURGERY
(2022)
Article
Medicine, General & Internal
Raffaele Nuzzi, Flavia Tripoli, Alessandro Rossi, Andrea Ghilardi
Summary: Keratoconus is a degenerative eye disease that causes corneal deformity and visual deterioration. Different methods can be used for correction depending on the stage of the disease. This study evaluated a patient with keratoconus who underwent a successful surgical procedure with good outcomes after 15 months of follow-up.
FRONTIERS IN MEDICINE
(2022)
Article
Ophthalmology
Mahmoud Jabbarvand, Hooman Ahmadzadeh, Mehdi Khodaparast, Alireza Jamali, Mohamadreza Aghamirsalim
Summary: The purpose of this study was to evaluate the efficacy and safety of implantation of a new continuous corneal ring in keratoconic corneas of an Iranian population. The results showed that this implantation method effectively improved visual acuity and refractive outcomes, and had a high level of safety.
Article
Ophthalmology
Seyed Javad Hashemian, Parya Abdolalizadeh, Leila Ghiasian, Hossein Aghaei, Ali Hadavandkhani, Fatemeh Nadjafi Semnani, Mohammad Ebrahim Jafari, Seyed Mahyar Hashemian, Mahsa Sadat Hashemian
Summary: The study found that a single-segment intrastromal corneal ring segment implantation can improve visual acuity, refractive errors, and keratometry values in patients with early keratoconus and pellucid marginal degeneration.
INTERNATIONAL OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Lucia Ibares-Frias, Luis Fernandez-Vega-Cueto, Belen Alfonso-Bartolozzi, Aranzazu Poo-Lopez, David Madrid-Costa, Jose F. Alfonso
Summary: This study evaluated the outcomes of implanting a 150 degrees arc-length intrastromal corneal ring segment (ICRS) in patients with post-LASIK ectasia. The results showed that the procedure was safe, effective, and stable, leading to visual restoration in these patients.
CURRENT EYE RESEARCH
(2023)
Article
Biology
Francisco Arnalich-Montiel, Carlota Fuente, Clara Auladell, Sara Ortiz-Toquero
Summary: Confirming the progression of keratoconus is crucial for proper treatment, and it should exceed the variability of corneal monitoring devices to be considered real change. This study aimed to evaluate the repeatability and reproducibility of a Scheimpflug camera in measuring corneal parameters in keratoconus and ICRS eyes. The results showed better precision and narrower limits of repeatability and reproducibility in keratoconus eyes compared to ICRS eyes. The cutoff values to determine genuine corneal shape change were different between keratoconus and ICRS eyes, and corneal tomography measurements were less accurate in ICRS eyes.
Article
Ophthalmology
Francesco D'Oria, Ahmed A. Abdelghany, Natalia Ledo, Rafael Barraquer, Jorge L. Alio
Summary: The study reviewed consecutive cases of intrastromal corneal ring segments explanted in the last 10 years to determine the main causes and define the incidence rate. Functional failure, particularly refractive failure, was found to be the main reason for explantation followed by anatomic failure, with spontaneous extrusion being a common issue in advanced cases of keratoconus.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Ophthalmology
Abbas Bagheri, Amirreza Veisi, Mehdi Tavakoli
Summary: HVRT combined with MRrec is an effective procedure to improve esotropia, face turn, and abduction limitation in CSNP and eDRS.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Amirreza Veisi, Abbas Bagheri, Mohammad Eshaghi, Mohamad Hasan Rikhtehgar, Mozhgan Rezaei Kanavi, Reza Farjad
Summary: This report presents two cases of COVID-19 patients treated with corticosteroid developing mucormycosis, emphasizing the importance of prompt diagnosis and management.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Abbas Bagheri, Amirreza Veisi, Mehdi Tavakoli
Summary: The study reports the outcomes of MR disinsertion procedure in patients with chronic complete sixth nerve palsy and refractory diplopia. The procedure improved ET in most cases, with some needing additional surgeries.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Clinical Neurology
Amirreza Veisi, Maryam Najafi, Kiana Hassanpour, Abbas Bagheri
Summary: A broad range of neurological side effects, including cranial nerve palsies, have been reported after COVID-19 vaccination. We describe two male patients who developed facial nerve palsy and abducens nerve palsy after receiving the vaccines. Both patients showed gradual recovery. Further studies are needed to understand the relationship between cranial nerve palsies and vaccination.
NEURO-OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Abbas Bagheri, Mohammad Gozin, Amirreza Veisi, Mozhgan Rezaei Kanavi
Summary: This article presents a rare case of heterotopic brain tissue in a 7-year-old male child who exhibited severe globe displacement, proptosis, and vision loss in the right eye. The cystic mass was surgically removed and histopathological investigations confirmed the presence of heterotopic brain tissue.
ORBIT-THE INTERNATIONAL JOURNAL ON ORBITAL DISORDERS-OCULOPLASTIC AND LACRIMAL SURGERY
(2022)
Review
Ophthalmology
Narges Karrabi, Sadid Hooshmandi, Alireza Amirabadi, Danial Roshandel, Kiana Hassanpour, Mohammad Pakravan
Summary: Optic nerve head edema is a common clinical manifestation of various eye and systemic disorders, and imaging techniques are used to differentiate the underlying causes and monitor the disease progression. Optical coherence tomography angiography is a noninvasive imaging method that has been extensively used to study vascular changes in ONH disorders.
JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Fiona Stapleton, Juan Carlos Abad, Stefano Barabino, Anthea Burnett, Geetha Iyer, Kaevalin Lekhanont, Tianjing Li, Yang Liu, Alejandro Navas, Chukwuemeka Junior Obinwanne, Riaz Qureshi, Danial Roshandel, Afsun Sahin, Kendrick Shih, Anna Tichenor, Lyndon Jones
Summary: A framework was used to map societal factors associated with ocular surface diseases, considering the individual, health, and environment. The impact of the COVID-19 pandemic and mitigating factors on ocular surface diseases were reviewed systematically. Age and sex effects are well-characterized for various types of ocular surface diseases. Sex and gender, genetic factors, race, smoking, and co-morbidities have interdependencies with geographical, employment, and socioeconomic factors. Living and working conditions, as well as regional and global socio-economic, cultural, and environmental conditions, play a role in the prevalence and severity of ocular surface diseases. Digital technology, conflicts, natural disasters, and the pandemic influence access to health services. The COVID-19 pandemic and related strategies have increased the risk of developing or worsening ocular surface diseases.
Article
Ophthalmology
Danial Roshandel, Farbod Semnani, Amirmasoud Rayati Damavandi, Ali Masoudi, Alireza Baradaran-Rafii, Stephanie L. Watson, William H. Morgan, Samuel McLenachan
Summary: The ocular surface, consisting of the corneal and conjunctival epithelium, plays a crucial role in maintaining ocular integrity and function. Gene defects can lead to ocular surface disorders, either as congenital conditions or through the interaction of genetic and environmental factors. Advanced gene-based technologies have shown promise in disease modeling and gene therapy for monogenic ocular surface disorders. Understanding the genetic factors involved in both monogenic and multifactorial ocular surface disorders could pave the way for personalized disease models and treatment strategies.
Review
Medicine, General & Internal
Helia Ashourizadeh, Maryam Fakhri, Kiana Hassanpour, Ali Masoudi, Sattar Jalali, Danial Roshandel, Fred K. Chen
Summary: Adaptive optics (AO) retinal imaging allows for the visualization of individual photoreceptors in a clinical setting, which is crucial for studying photoreceptor degeneration. AO imaging is a powerful clinical tool that can detect cellular-level degeneration that may be missed by traditional methods. It is also useful for early-stage diagnosis and monitoring disease progression. However, caution should be exercised when interpreting AO imaging results due to various factors that can affect image quality and normal values.
Article
Public, Environmental & Occupational Health
Sheikh Mohammed Shariful Islam, Mohammed Islam
Summary: A comprehensive analysis of the Global Burden of Disease Study (GBD) 2019 revealed the disease burden and trends in Australia from 1990 to 2019. Non-communicable diseases remained the leading cause of mortality in Australia, with low back pain, depressive disorders, and other musculoskeletal diseases being the main contributors to disability-adjusted life-years (DALYs). High BMI, smoking, high blood pressure, high fasting plasma glucose, and drug use were identified as the leading risk factors for DALYs. Australia's ranking improved for death rates and life expectancy, but not for years lived with disability (YLDs) and years of life lost (YLLs) compared to similar countries.
LANCET PUBLIC HEALTH
(2023)
Article
Ophthalmology
Danial Roshandel, Tina M. Lamey, Jason Charng, Rachael C. Heath Jeffery, Terri L. McLaren, Jennifer A. Thompson, John N. De Roach, Samuel McLenachan, David A. Mackey, Fred K. Chen
Summary: Microperimetry and adaptive optics imaging revealed early functional and structural changes in asymptomatic RPGR mutation carriers, suggesting the importance of considering these assessments in the clinical evaluation of these patients.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2023)
Article
Education, Scientific Disciplines
Mehdi Raadabadi, Sara Emamgholipour, Rajabali Daroudi, Farzan Madadizadeh, Amirreza Veisi
Summary: The study aimed to evaluate the health-related quality of life (HRQoL) among adults with visual problems in 2021. The results showed that HRQoL was moderate in patients with visual impairments, but reduced in patients with high disease severity, old age, lack of a spouse, retirement, and nonuniversity education.
JOURNAL OF EDUCATION AND HEALTH PROMOTION
(2022)
Meeting Abstract
Ophthalmology
Danial Roshandel, Tina M. Lamey, Jason Charng, Rachael C. Heath Jeffery, Terri L. McLaren, Jennifer A. Thompson, John N. De Roach, Samuel McLenachan, David A. Mackey, Fred Kuanfu Chen
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)
Review
Health Care Sciences & Services
Elham Nazari, Rizwana Biviji, Danial Roshandel, Reza Pour, Mohammad Hasan Shahriari, Amin Mehrabian, Hamed Tabesh
Summary: This article provides an overview of the decision fusion technique and its applications in healthcare and medicine. It emphasizes the importance of big data analysis and the potential role of decision fusion in improving healthcare quality. The article suggests further research on the methodology and data types used in decision fusion within the healthcare sector.
Article
Ophthalmology
Danial Roshandel, Danuta M. Sampson, David A. Mackey, Fred K. Chen
Summary: This study investigates the discordance between the adaptive optics (AO) montage center (AMC) and the foveal pit center (FPC) and its implications for cone mosaic analysis. The results show a marked mismatch between the AMC and FPC, which may be modified by diseases such as rod-cone dystrophy. The distance between AMC and FPC is a significant determinant of cone density and inter-cone distance.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)