Article
Dentistry, Oral Surgery & Medicine
Ahmed Yaseen Alqutaibi, Sary Borzangy, Sadeq A. Al-Maweri, Afaf Aboalrejal
Summary: Prosthodontists in Saudi Arabia show a relatively positive attitude towards oral cancer screening, but have lower rates of examination at recall visits and providing smoking cessation advice. Most prosthodontists believe they can detect oral cancer themselves, but barriers such as training, confidence, time, and financial incentives still exist.
JOURNAL OF PROSTHETIC DENTISTRY
(2021)
Review
Pharmacology & Pharmacy
Pratima Kumari, Priyanka Debta, Anshuman Dixit
Summary: Oral cancer is a critical health issue, with the majority of new cases occurring in Asia. Various factors, such as genetics and lifestyle, are closely associated with its occurrence and progression. Early signs of oral cancer include oral lesions, genetic mutations, and viral infections. Lesions with dysplastic features have a high risk of malignancy, and OPMDs have a high prevalence in South Asian countries. Early detection, prevention, and treatment of OPMDs are crucial.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Oncology
Kazuki Mori, Tomofumi Hamada, Mahiro Beppu, Hiroki Tsuchihashi, Yuichi Goto, Kenichi Kume, Hiroshi Hijioka, Keitaro Nishi, Yumiko Mishima, Tsuyoshi Sugiura
Summary: Using gargle fluid as a noninvasive screening tool can accurately diagnose early-stage oral cancer and distinguish it from oral potentially malignant disorders (OPMDs). The methylation panel of genes in gargle fluid is a reliable and noninvasive method for early cancer detection.
Article
Health Care Sciences & Services
Olga Di Fede, Vera Panzarella, Fortunato Buttacavoli, Gaetano La Mantia, Giuseppina Campisi
Summary: Oral potentially malignant disorders are mucosal lesions and conditions with a higher risk of cancer development. Unfortunately, these disorders are often diagnosed late due to lack of attention in routine dental practice and a limited number of specialized oral medicine centers. This report discusses the DoctOral experience, which offers a smartphone-based decision support tool for healthcare professionals, allowing for immediate examination and diagnosis of oral lesions through interactive decision trees. The DoctOral mobile app has successfully revolutionized oral pathology by serving as an interactive platform for dental students and professionals to recognize and diagnose oral lesions.
Article
Multidisciplinary Sciences
Praveen N. Birur, Bofan Song, Sumsum P. Sunny, G. Keerthi, Pramila Mendonca, Nirza Mukhia, Shaobai Li, Sanjana Patrick, G. Shubha, A. R. Subhashini, Tsusennaro Imchen, Shirley T. Leivon, Trupti Kolur, Vivek Shetty, Vidya R. Bhushan, Daksha Vaibhavi, Surya Rajeev, Sneha Pednekar, Ankita Dutta Banik, Rohan Michael Ramesh, Vijay Pillai, O. S. Kathryn, Petra Wilder Smith, Alben Sigamani, Amritha Suresh, Rongguang Liang, Moni A. Kuriakose
Summary: This study tested the accuracy of a mobile health device, enabled with Convolutional Neural Network (CNN), for early detection of oral cancer in low-resource settings. The device accurately identified suspicious oral lesions, empowering frontline health workers in screening for oral cancer.
SCIENTIFIC REPORTS
(2022)
Article
Oncology
Vivek Talwar, Pragya Singh, Nirza Mukhia, Anupama Shetty, Praveen Birur, Karishma M. Desai, Chinnababu Sunkavalli, Konala S. Varma, Ramanathan Sethuraman, C. V. Jawahar, P. K. Vinod
Summary: The prevalence of oral potentially malignant disorders and oral cancer is increasing in low- and middle-income countries. A lack of resources for population screening in remote areas leads to delayed detection of these disorders, resulting in higher mortality and poor quality of life. This study explores the use of artificial intelligence and digital imaging for detecting these disorders using smartphone-captured oral cavity images. The proposed model shows promising results in identifying suspicious and non-suspicious oral lesions, and can assist in early detection and referral for treatment of these disorders.
Review
Dentistry, Oral Surgery & Medicine
Rishi S. Ramani, Ivy Tan, Lindsay Bussau, Christopher M. Angel, Michael McCullough, Tami Yap
Summary: Confocal microscopy has been explored for its utility in diagnosing oral squamous cell carcinoma and oral epithelial dysplasia. Quantitative software-based studies show potential in objectifying the diagnostic process for identifying abnormalities within the oral mucosa.
Review
Dentistry, Oral Surgery & Medicine
Alexander Ross Kerr, Giovanni Lodi
Summary: Managing patients with oral potentially malignant disorders is challenging due to the lack of understanding of natural history and validated predictive markers. Evidence-based health promotion is not widely embraced, and research on medical interventions often suffers from methodologic flaws and lack of focus on patient quality of life. Global networks with well-characterized patient populations are needed for better intervention trials.
Article
Oncology
Gizem Tanriver, Merva Soluk Tekkesin, Onur Ergen
Summary: Oral cancer is the most common type of head and neck cancer worldwide, with early detection leading to high survival rates. However, lack of public awareness and delays in referrals contribute to late-stage diagnoses. This study explores the use of deep learning and computer vision techniques for automated detection and classification of oral potentially malignant disorders, offering a low-cost and non-invasive tool to improve screening processes and detection outcomes.
Review
Health Care Sciences & Services
Jewel Kai Lin See, Xinyao Liu, Federica Canfora, Caroline Moore, Michael Mccullough, Tami Yap, Rita Paolini, Antonio Celentano
Summary: This study systematically reviewed the evidence on the therapeutic effects of vitamin supplementation for oral potentially malignant disorders (OPMDs) and oral cancer (OC). The results showed that vitamin K, vitamin C, vitamin A, vitamin B, and vitamin D all had therapeutic benefits. The research on oral cancer was extensive, with a focus on oral lichen planus and oral leukoplakia among the OPMDs. However, standardizing the study design and outcomes is needed to enhance future research.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Medicine, General & Internal
Tanya Walsh, Saman Warnakulasuriya, Mark W. Lingen, Alexander R. Kerr, Graham R. Ogden, Anne-Marie Glenny, Richard Macey
Summary: This study aimed to evaluate the accuracy of different methods for early detection of oral cavity cancer, such as conventional oral examination, light-based detection, remote screening, and biomarker analysis. The results indicate that caution should be exercised in screening for oral cancer, as there is insufficient evidence to support the use of screening programs.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Article
Multidisciplinary Sciences
Sivaraj Raman, Asrul Akmal Shafie, Mannil Thomas Abraham, Chen Kiong Shim, Thaddius Herman Maling, Senthilmani Rajendran, Sok Ching Cheong
Summary: Oral cancer poses a significant challenge to healthcare systems, particularly in Malaysia. This study aimed to determine the cost of treating oral potentially malignant disorders (OPMD) and oral cancer from a public healthcare provider's perspective. The research found that the cost of treating oral cancer is significantly higher than that of OPMD, with surgical care and personnel costs being the main contributors to the higher expenditure.
Article
Dentistry, Oral Surgery & Medicine
Boworn Klongnoi, Vanvisa Sresumatchai, Harin Clypuing, Angkana Wisutthajaree, Jintana Pankam, Natchalee Srimaneekarn, Binit Shrestha, Siribang-on Piboonniyom Khovidhunkit
Summary: This study conducted a screening program for lip and oral cavity cancer in northeastern Thailand, revealing the common histopathological findings and associated risk factors. The habit of betel quid chewing was found to be associated with oral cancer.
Article
Oncology
Fredrik Jawert, Jennie Nyman, Emma Olsson, Claudia Adok, Madeleine Helmersson, Jenny Ohman
Summary: Regular follow-up of patients with oral potentially malignant disorders (OPMD) leads to earlier detection of oral squamous cell carcinoma (OSCC) and improved survival rates, as indicated by the study results.
Review
Medicine, General & Internal
Tanya Walsh, Richard Macey, Alexander R. Kerr, Mark W. Lingen, Graham R. Ogden, Saman Warnakulasuriyas
Summary: Squamous cell carcinoma is the most common malignancy of the oral cavity, and early detection can improve survival rates. The current diagnostic standard involves surgical biopsy with histology, but less invasive diagnostic tests are available for immediate results.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Article
Education & Educational Research
Susan Hattar, Abeer AlHadidi, Faleh A. Sawair, Islam Abd Alraheam, Ahmad El-Ma'aita, Fouad Kadim Wahab
Summary: This study investigated the impact of quarantine on the self-perceived preparedness of dental graduates and explored students' perspectives on online education. Most students missed educational experiences due to the lockdown, felt less motivated for distant e-learning, and were skeptical about online assessment. However, a high percentage believed in the value of online group discussions and preferred online lectures over theatre lectures.
BMC MEDICAL EDUCATION
(2021)
Article
Health Care Sciences & Services
Nesreen A. Salim, Shroq Hafedh Meyad, Faleh A. Sawair, Julian D. Satterthwaite, Samiha Sartawi
Summary: This study found that refugees in Zaatari camp are generally satisfied with the medical and dental services provided, with areas for improvement identified. Younger participants and those with shorter stays in the camp showed higher satisfaction rates. Interaction and reactivity domain achieved the highest satisfaction score, while administration efficiency domain was ranked the lowest.
BMC HEALTH SERVICES RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Joanne Cunliffe, Abeer Al-Hadidi, Faleh A. Sawair, Sari A. Mahasneh
Summary: The study found that using CBCT scans can more accurately diagnose external cervical resorption lesions compared to intraoral radiographs, and when participants were told the radiograph and CBCT were of the same tooth, 60% said they would change their diagnosis. Intraoral radiographs alone may not be sufficient to accurately diagnose this condition.
Article
Pediatrics
Nesreen A. Salim, Faleh A. Sawair, Fatima Hafedh Meyad, Julian D. Satterthwaite, Ashraf Abukaraky, Samiha Sartawi
Summary: The Syrian conflict has greatly affected the dental health of refugees, with dental caries and pulpal diseases being the most common causes for tooth extraction. Parental education level and toothbrushing frequency are associated with a lower number of extractions and a decrease in extractions due to caries.
Article
Dentistry, Oral Surgery & Medicine
Ayah A. Al-Asmar, Ahmad S. Al-Hiyasat, Motasum Abu-Awwad, Hakam N. Mousa, Nesreen A. Salim, Waed Almadani, Furat Rihan, Faleh A. Sawair, Nigel B. Pitts
Summary: This study investigated the contemporary practice of restorative dentistry among dentists in Jordan and their decision-making process, revealing common trends in treating irreversible pulpitis, severely damaged teeth, and performing smile makeovers. It also found a higher implementation of evidence-based dentistry in clinical decision-making in Prosthetic Dentistry compared to Endodontics, indicating a need to bridge the gap between evidence-based data and clinical practice.
INTERNATIONAL JOURNAL OF DENTISTRY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Yazan Hassona, Nesreen A. Salim, Nafez Tarboush, Samiha Sartawi, Mohammad Alrashdan, Lamis Rajab, Faleh Sawair
Summary: The study reveals that medical students lack knowledge and confidence in recognizing oral manifestations of systemic diseases, with dental students performing significantly better in this aspect. Medical students reported a need for more formal training in oral examination and disease diagnosis.
SPECIAL CARE IN DENTISTRY
(2022)
Article
Chemistry, Multidisciplinary
Sari A. Mahasneh, Abeer Al-Hadidi, Yazan Hassona, Faleh A. Sawair, Sarah Al-Nazer, Yara Bakain, Joanne Cunliffe
Summary: The study found a correlation between maxillary sinus mucosal thickening and odontogenic pathology of adjacent teeth, with significant differences observed between different types of teeth. Odontogenic sinusitis is more likely to occur near the first and second molars.
APPLIED SCIENCES-BASEL
(2022)
Article
Dentistry, Oral Surgery & Medicine
Nesreen A. A. Salim, Faleh A. A. Sawair, Ziad Abusidu, Aseel M. M. Sharaireh, Julian D. D. Satterthwaite, Yazan Hassona
Summary: The Syrian crisis has had a significant impact on the oral health status of refugees. This study aimed to analyze the pattern of tooth extraction among Syrian refugees in the Zaatari camp and identify associated sociodemographic factors. The results showed that dental caries was the leading cause of tooth extraction, with molar teeth being the most frequently extracted. Older age, smoking, lower education level, poor oral hygiene, and male gender were all associated with a higher incidence of tooth extractions.
SPECIAL CARE IN DENTISTRY
(2022)
Article
Information Science & Library Science
Latefa Ali Dardas, Malik Sallam, Amanda Woodward, Nadia Sweis, Narjes Sweis, Faleh A. Sawair
Summary: This study aimed to explore the added value of Semantic Scholar (SS) Highly Influential Citations (HICs) compared to total citation counts and Altmetric Attention Score (AAS) in measuring research impact. The results showed that the calculation method of SS HICs is unclear and heavily dependent on artificial intelligence, leading to contradictions and flaws. Continuous evaluation of existing tools and the development of novel approaches are recommended to improve the reliability of publication impact assessment.
Review
Chemistry, Multidisciplinary
Mohammed Adel Awawdeh, Rekha Sasikumar, Ali Anwar Aboalela, Salman Siddeeqh, Pillai Arun Gopinathan, Faleh Sawair, Sanjeev B. Khanagar
Summary: The majority of head and neck tumours are squamous cell carcinomas (SCC), and recent advancements have provided evidence for their genetic origins. Identifying prognostic biomarkers in oral SCC is crucial for predicting tumour behaviour and planning treatment. Many studies have shown that combining chemotherapy with radiotherapy improves treatment outcomes and overall survival. Biomarkers such as p53, cyclin D1, and EGFR play a pivotal role in tumour development and progression. This systematic review aims to analyze the prognostic significance of the expression of p53, cyclin D1, and EGFR in advanced oral SCC after chemoradiation therapy.
APPLIED SCIENCES-BASEL
(2023)
Article
Medicine, General & Internal
Sari A. Mahasneh, Abeer Al-Hadidi, Fouad Kadim Wahab, Faleh A. Sawair, Mohammad Abdalla AL-Rabab'ah, Sarah Al-Nazer, Yara Bakain, Cosimo Nardi, Joanne Cunliffe
Summary: The aim of this study was to investigate the relationship between the degree of bone loss around teeth, vitality of adjacent teeth, and periapical disease. The results showed a significant association between crestal bone loss and the need for root canal treatment. Buccal or lingual crestal bone loss was also significantly associated with a higher rate of periapical disease. Cone-beam computed tomography scans were effective in identifying the severity of bone loss on all surfaces of the teeth.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Yazan Hassona, Dana Altoum, Dua'a Alqaisi, Dina Taimeh, Faleh Sawair
Summary: The management of chronic oral mucosal diseases can be challenging in older individuals with intellectual disability due to associated comorbidities, variable clinical presentations, and barriers imposed by the disability itself. This report discusses the presentation and management of pemphigus vulgaris in an older female with severe intellectual disability.
SPECIAL CARE IN DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Nesreen A. Salim, Faleh A. Sawair, Julian D. Satterthwaite, Zainab Al-Zubi
Summary: The study characterized the oral hygiene habits of refugees in Jordan, revealing high prevalence of caries and poor oral hygiene practices, highlighting the urgent need for targeted oral health promotion programs and treatment strategies.
ORAL HEALTH & PREVENTIVE DENTISTRY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Nesreen A. Salim, Lyn A. El-Smadi, Faleh A. Sawair, Julian D. Satterthwaite
Summary: The study found that parental acceptance of SDF treatment for their children is low. However, staining on posterior teeth was more acceptable than staining on anterior teeth, and staining on primary teeth was more acceptable than on permanent teeth.
COMMUNITY DENTAL HEALTH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Fouad Kadim Wahab, Sari Adel Mahasneh, Faleh Abdelhafeeth Sawair, Mahmoud Anwar Hamdan, Susan Nweiser Hattar, Mohammad Abdalla AL-Rabab'ah
Summary: The study revealed that the majority of Jordanian dentists prefer using metal ceramic and all-ceramic crowns over endocrowns when restoring root filled teeth. Additionally, fiber posts are the most popular type of posts, and loss of post/core retention or fracture of coronal tooth structure are the two most common reasons observed by dentists when RFT fail. Further training on evidence-based adhesive strategies could improve the longevity of restorations.
OPEN DENTISTRY JOURNAL
(2021)
