4.5 Article

Lipidomics informatics for life-science

Journal

JOURNAL OF BIOTECHNOLOGY
Volume 261, Issue -, Pages 131-136

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.jbiotec.2017.08.010

Keywords

LIFS; Lipidomics; Bioinformatics; LipidXplorer; Lux-Score; LipidCreator; Skyline

Funding

  1. Ministerium fur Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen
  2. Senatsverwaltung fur Wirtschaft, Technologie und Forschung des Landes Berlin
  3. Bundesministerium fur Bildung und Forschung, SUPR-G e: Med [01ZX1401C]
  4. de.NBI program [031L0108A, 031L0108B, 031L0108C]

Ask authors/readers for more resources

Lipidomics encompasses analytical approaches that aim to identify and quantify the complete set of lipids, defined as lipidome in a given cell, tissue or organism as well as their interactions with other molecules. The majority of lipidomics workflows is based on mass spectrometry and has been proven as a powerful tool in system biology in concert with other Omics disciplines. Unfortunately, bioinformatics infrastructures for this relatively young discipline are limited only to some specialists. Search engines, quantification algorithms, visualization tools and databases developed by the 'Lipidomics Informatics for Life-Science' (LIFS) partners will be restructured and standardized to provide broad access to these specialized bioinformatics pipelines. There are many medical challenges related to lipid metabolic alterations that will be fostered by capacity building suggested by LIFS. LIFS as member of the 'German Network for Bioinformatics' (de. NBI) node for 'Bioinformatics for Proteomics' (BioInfra. Prot) and will provide access to the described software as well as to tutorials and consulting services via a unified web-portal.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.5
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available