Autofluorescence imaging identifies tumor cell-cycle status on a single-cell level

Metabolic Imaging of Head and Neck Cancer Organoids

(2017) Amy T. Shah et al.   PLoS One

Optical Imaging of Drug-Induced Metabolism Changes in Murine and Human Pancreatic Cancer Organoids Reveals Heterogeneous Drug Response

(2016) Alex J. Walsh et al.   PANCREAS

A tutorial review: Metabolomics and partial least squares-discriminant analysis – a marriage of convenience or a shotgun wedding

(2015) Piotr S. Gromski et al.   ANALYTICA CHIMICA ACTA

Optical metabolic imaging quantifies heterogeneous cell populations

(2015) Alex J. Walsh et al.   Biomedical Optics Express

In Vivo Autofluorescence Imaging of Tumor Heterogeneity in Response to Treatment

(2015) Amy T. Shah et al.   NEOPLASIA

Metabolic Regulation of Immune Responses

(2014) Kirthana Ganeshan et al.   Annual Review of Immunology

c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells

(2014) J. E. Roderick et al.   BLOOD

Quantitative Optical Imaging of Primary Tumor Organoid Metabolism Predicts Drug Response in Breast Cancer

(2014) A. J. Walsh et al.   CANCER RESEARCH

Endogenous Two-Photon Fluorescence Imaging Elucidates Metabolic Changes Related to Enhanced Glycolysis and Glutamine Consumption in Precancerous Epithelial Tissues

(2014) A. Varone et al.   CANCER RESEARCH

Partial least squares discriminant analysis: taking the magic away

(2014) Richard G. Brereton et al.   JOURNAL OF CHEMOMETRICS

Separating NADH and NADPH fluorescence in live cells and tissues using FLIM

(2014) Thomas S. Blacker et al.   Nature Communications

Optical Metabolic Imaging Identifies Glycolytic Levels, Subtypes, and Early-Treatment Response in Breast Cancer

(2013) A. J. Walsh et al.   CANCER RESEARCH

BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells

(2013) Eleni D. Lagadinou et al.   Cell Stem Cell

A Triple Staining Method for Accurate Cell Cycle Analysis Using Multiparameter Flow Cytometry

(2013) Lin Qiu et al.   MOLECULES

Influence of tumour micro-environment heterogeneity on therapeutic response

(2013) Melissa R. Junttila et al.   NATURE

Optical Imaging Using Endogenous Contrast to Assess Metabolic State

(2012) Irene Georgakoudi et al.   Annual Review of Biomedical Engineering

Ex vivooptical metabolic measurements from cultured tissue reflectin vivotissue status

(2012) Alex J. Walsh et al.   JOURNAL OF BIOMEDICAL OPTICS

Driving the Cell Cycle Through Metabolism

(2011) Ling Cai et al.   Annual Review of Cell and Developmental Biology

Optical imaging of metabolism in HER2 overexpressing breast cancer cells

(2011) Alex Walsh et al.   Biomedical Optics Express

Intracellular coenzymes as natural biomarkers for metabolic activities and mitochondrial anomalies

(2010) Ahmed A Heikal   Biomarkers in Medicine

Selective inhibition of BET bromodomains

(2010) Panagis Filippakopoulos et al.   NATURE

Fluorescence Lifetime Imaging of Endogenous Fluorophores in Histopathology Sections Reveals Differences Between Normal and Tumor Epithelium in Carcinoma In Situ of the Breast

(2009) Matthew W. Conklin et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction

(2009) Ismael Samudio et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial function and energy metabolism in cancer cells: Past overview and future perspectives

(2009) Avraham Mayevsky   MITOCHONDRION