Protein 19F-labeling using transglutaminase for the NMR study of intermolecular interactions

The role of dimer asymmetry and protomer dynamics in enzyme catalysis

(2017) Tae Hun Kim et al.   SCIENCE

Applications of 19F-NMR in Fragment-Based Drug Discovery

(2016) Raymond Norton et al.   MOLECULES

Structural basis for activity regulation of MLL family methyltransferases

(2016) Yanjing Li et al.   NATURE

Activation of the A2A adenosine G-protein-coupled receptor by conformational selection

(2016) Libin Ye et al.   NATURE

Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation

(2016) Dean P. Staus et al.   NATURE

Fragment Screening and Druggability Assessment for the CBP/p300 KIX Domain through Protein-Observed19F NMR Spectroscopy

(2015) Clifford T. Gee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural Insights into the Dynamic Process of β 2 -Adrenergic Receptor Signaling

(2015) Aashish Manglik et al.   CELL

A comparison of chemical shift sensitivity of trifluoromethyl tags: optimizing resolution in 19F NMR studies of proteins

(2015) Libin Ye et al.   JOURNAL OF BIOMOLECULAR NMR

Protein-Observed Fluorine NMR: A Bioorthogonal Approach for Small Molecule Discovery

(2015) Keith E. Arntson et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Selective NMR Probe to Monitor the Conformational Transition from Inactive to Active Kinase

(2014) Qian Xie et al.   ACS Chemical Biology

Fluorinated Aromatic Amino Acids Are Sensitive 19F NMR Probes for Bromodomain-Ligand Interactions

(2014) Neeraj K. Mishra et al.   ACS Chemical Biology

Versatility of Microbial Transglutaminase

(2014) Pavel Strop   BIOCONJUGATE CHEMISTRY

19F NMR as a Probe of Ligand Interactions with the iNOS Binding site of SPRY Domain-Containing SOCS Box Protein 2

(2014) Eleanor W. W. Leung et al.   Chemical Biology & Drug Design

19F NMR Reveals Multiple Conformations at the Dimer Interface of the Nonstructural Protein 1 Effector Domain from Influenza A Virus

(2014) James M. Aramini et al.   STRUCTURE

Recent applications of isotopic labeling for protein NMR in drug discovery

(2013) Hidekazu Hiroaki   Expert Opinion on Drug Discovery

Local Unfolding Is Required for the Site-Specific Protein Modification by Transglutaminase

(2012) Barbara Spolaore et al.   BIOCHEMISTRY

Utilization of lysine 13C-methylation NMR for protein–protein interaction studies

(2012) Yoshikazu Hattori et al.   JOURNAL OF BIOMOLECULAR NMR

Lysine methylation strategies for characterizing protein conformations by NMR

(2012) Sacha Thierry Larda et al.   JOURNAL OF BIOMOLECULAR NMR

Biased Signaling Pathways in  2-Adrenergic Receptor Characterized by 19F-NMR

(2012) J. J. Liu et al.   SCIENCE

Site-Directed Methyl Group Labeling as an NMR Probe of Structure and Dynamics in Supramolecular Protein Systems: Applications to the Proteasome and to the ClpP Protease

(2011) Tomasz L. Religa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

14-3-3 proteins act as intracellular receptors for rice Hd3a florigen

(2011) Ken-ichiro Taoka et al.   NATURE

Current applications of 19F NMR to studies of protein structure and dynamics

(2011) Julianne L. Kitevski-LeBlanc et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Screening for improved activity of a transglutaminase from Streptomyces mobaraensis created by a novel rational mutagenesis and random mutagenesis

(2010) Keiichi Yokoyama et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Probing the Micelle-Bound Aggregation-Prone State of α-Synuclein with 19F NMR Spectroscopy

(2010) Gui-Fang Wang et al.   CHEMBIOCHEM

Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor

(2010) Michael P. Bokoch et al.   NATURE

19F NMR studies of α-synuclein-membrane interactions

(2010) Gui-Fang Wang et al.   PROTEIN SCIENCE

Substrate specificity of microbial transglutaminase as revealed by three-dimensional docking simulation and mutagenesis

(2009) U. Tagami et al.   PROTEIN ENGINEERING DESIGN & SELECTION

pCold-GST vector: A novel cold-shock vector containing GST tag for soluble protein production

(2008) Kokoro Hayashi et al.   PROTEIN EXPRESSION AND PURIFICATION

Site-specific modification and PEGylation of pharmaceutical proteins mediated by transglutaminase

(2007) Angelo Fontana et al.   ADVANCED DRUG DELIVERY REVIEWS