NMR characterization of HtpG, the E. coli Hsp90, using sparse labeling with 13C-methyl alanine

NMR assignments of sparsely labeled proteins using a genetic algorithm

(2017) Qi Gao et al.   JOURNAL OF BIOMOLECULAR NMR

Structural Aspects of Heparan Sulfate Binding to Robo1–Ig1–2

(2016) Qi Gao et al.   ACS Chemical Biology

Cooperation of local motions in the Hsp90 molecular chaperone ATPase mechanism

(2016) Andrea Schulze et al.   Nature Chemical Biology

Atomic structure of Hsp90-Cdc37-Cdk4 reveals that Hsp90 traps and stabilizes an unfolded kinase

(2016) K. A. Verba et al.   SCIENCE

PPM_One: a static protein structure based chemical shift predictor

(2015) Dawei Li et al.   JOURNAL OF BIOMOLECULAR NMR

Solution NMR Spectroscopy Provides an Avenue for the Study of Functionally Dynamic Molecular Machines: The Example of Protein Disaggregation

(2015) Rina Rosenzweig et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chaperones and chaperone–substrate complexes: Dynamic playgrounds for NMR spectroscopists

(2015) Björn M. Burmann et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Bringing Dynamic Molecular Machines into Focus by Methyl-TROSY NMR

(2014) Rina Rosenzweig et al.   Annual Review of Biochemistry

Hsp90-Tau Complex Reveals Molecular Basis for Specificity in Chaperone Action

(2014) G. Elif Karagöz et al.   CELL

Structural Asymmetry in the Closed State of Mitochondrial Hsp90 (TRAP1) Supports a Two-Step ATP Hydrolysis Mechanism

(2014) Laura A. Lavery et al.   MOLECULAR CELL

The dynamic duo: Combining NMR and small angle scattering in structural biology

(2014) Janosch Hennig et al.   PROTEIN SCIENCE

Three-Dimensional Protein Fold Determination from Backbone Amide Pseudocontact Shifts Generated by Lanthanide Tags at Multiple Sites

(2013) Hiromasa Yagi et al.   STRUCTURE

The Therapeutic Target Hsp90 and Cancer Hallmarks

(2012) Yoshihiko Miyata et al.   CURRENT PHARMACEUTICAL DESIGN

Protein Structure Determination from Pseudocontact Shifts Using ROSETTA

(2012) Christophe Schmitz et al.   JOURNAL OF MOLECULAR BIOLOGY

Targeting the Hsp90 Molecular Chaperone with Novel Macrolactams. Synthesis, Structural, Binding, and Cellular Studies

(2011) James E. H. Day et al.   ACS Chemical Biology

Hsp90 structure and function studied by NMR spectroscopy

(2011) Tatiana Didenko et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

An optimized isotopic labelling strategy of isoleucine-γ2methyl groups for solution NMR studies of high molecular weight proteins

(2011) Isabel Ayala et al.   CHEMICAL COMMUNICATIONS

Cross-Monomer Substrate Contacts Reposition the Hsp90 N-Terminal Domain and Prime the Chaperone Activity

(2011) Timothy O. Street et al.   JOURNAL OF MOLECULAR BIOLOGY

Client-Loading Conformation of the Hsp90 Molecular Chaperone Revealed in the Cryo-EM Structure of the Human Hsp90:Hop Complex

(2011) Daniel R. Southworth et al.   MOLECULAR CELL

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Conformational dynamics of the molecular chaperone Hsp90

(2011) Kristin A. Krukenberg et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Spinach – A software library for simulation of spin dynamics in large spin systems

(2010) H.J. Hogben et al.   JOURNAL OF MAGNETIC RESONANCE

The high-throughput protein sample production platform of the Northeast Structural Genomics Consortium

(2010) Rong Xiao et al.   JOURNAL OF STRUCTURAL BIOLOGY

Alanine Methyl Groups as NMR Probes of Molecular Structure and Dynamics in High-Molecular-Weight Proteins

(2010) Raquel Godoy-Ruiz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Activation of the Hsp90 Dimer by Its Cochaperone Aha1

(2010) Marco Retzlaff et al.   MOLECULAR CELL

N-terminal domain of human Hsp90 triggers binding to the cochaperone p23

(2010) G. E. Karagoz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploring sparsely populated states of macromolecules by diamagnetic and paramagnetic NMR relaxation

(2010) G. Marius Clore   PROTEIN SCIENCE

An efficient protocol for the complete incorporation of methyl-protonated alanine in perdeuterated protein

(2009) Isabel Ayala et al.   JOURNAL OF BIOMOLECULAR NMR

Grp94, the endoplasmic reticulum Hsp90, has a similar solution conformation to cytosolic Hsp90 in the absence of nucleotide

(2009) Kristin A. Krukenberg et al.   PROTEIN SCIENCE

Probabilistic Interaction Network of Evidence Algorithm and its Application to Complete Labeling of Peak Lists from Protein NMR Spectroscopy

(2009) Arash Bahrami et al.   PLoS Computational Biology

Species-Dependent Ensembles of Conserved Conformational States Define the Hsp90 Chaperone ATPase Cycle

(2008) Daniel R. Southworth et al.   MOLECULAR CELL

Multiple Conformations of E. coli Hsp90 in Solution: Insights into the Conformational Dynamics of Hsp90

(2008) Kristin A. Krukenberg et al.   STRUCTURE