Characterization of wear debris from metal-on-metal hip implants during normal wear versus edge-loading conditions

Measurement outcomes from hip simulators

(2016) Danielle de Villiers et al.   PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE

The biological response to nanometre-sized polymer particles

(2015) Aiqin Liu et al.   Acta Biomaterialia

Toxicology of wear particles of cobalt-chromium alloy metal-on-metal hip implants Part I: Physicochemical properties in patient and simulator studies

(2015) Amy K. Madl et al.   Nanomedicine-Nanotechnology Biology and Medicine

Toxicology of wear particles of cobalt-chromium alloy metal-on-metal hip implants Part II: Importance of physicochemical properties and dose in animal and in vitro studies as a basis for risk assessment

(2015) Amy K. Madl et al.   Nanomedicine-Nanotechnology Biology and Medicine

CoCr wear particles generated from CoCr alloy metal-on-metal hip replacements, and cobalt ions stimulate apoptosis and expression of general toxicology-related genes in monocyte-like U937 cells

(2014) Olga M. Posada et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Consequences of exposure to peri-articular injections of micro- and nano-particulate cobalt–chromium alloy

(2013) Christopher Brown et al.   BIOMATERIALS

Increasing both CoCrMo-alloy particle size and surface irregularity induces increased macrophage inflammasome activation in vitro potentially through lysosomal destabilization mechanisms

(2013) Marco S. Caicedo et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology

(2013) Stefan Tenzer et al.   Nature Nanotechnology

Chemical speciation of nanoparticles surrounding metal-on-metal hips

(2012) Angela E. Goode et al.   CHEMICAL COMMUNICATIONS

Distribution of metal released from cobalt-chromium alloy orthopaedic wear particles implanted into air pouches in mice

(2012) Grace A. Afolaranmi et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Effect of femoral head size on the wear of metal on metal bearings in total hip replacements under adverse edge-loading conditions

(2012) Mazen Al-Hajjar et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Simple isolation method for the bulk isolation of wear particles from metal on metal bearing surfaces generated in a hip simulator test

(2012) Fang Lu et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Acute inflammatory response to cobalt chromium orthopaedic wear debris in a rodent air-pouch model

(2012) M. Akbar et al.   Journal of the Royal Society Interface

Molecular and immune toxicity of CoCr nanoparticles in MoM hip arthroplasty

(2012) Harinderjit S. Gill et al.   TRENDS IN MOLECULAR MEDICINE

The John Charnley Award: An Accurate and Extremely Sensitive Method to Separate, Display, and Characterize Wear Debris Part 2: Metal and Ceramic Particles

(2011) Fabrizio Billi et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

An analysis of metal ion levels in the joint fluid of symptomatic patients with metal-on-metal hip replacements

(2011) K. Davda et al.   JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME

Bioengineering reasons for the failure of metal-on-metal hip prostheses

(2011) J. Fisher   JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME

In vivobiodistribution of nanoparticles

(2011) Joao Paulo Mattos Almeida et al.   Nanomedicine

Characterization of metal-wear nanoparticles in pseudotumor following metal-on-metal hip resurfacing

(2011) Zhidao Xia et al.   Nanomedicine-Nanotechnology Biology and Medicine

Characterization of wear particles generated from CoCrMo alloy under sliding wear conditions

(2011) R. Pourzal et al.   WEAR

Time Evolution of the Nanoparticle Protein Corona

(2010) Eudald Casals et al.   ACS Nano

The chemical form of metallic debris in tissues surrounding metal-on-metal hips with unexplained failure

(2010) Alister J. Hart et al.   Acta Biomaterialia

Postmortem Study of Femoral Osteolysis Associated with Metal-on-Metal Articulation in Total Hip Replacement

(2010) Monika Huber et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Dose-dependent cytotoxicity of clinically relevant cobalt nanoparticles and ions on macrophagesin vitro

(2009) Young-Min Kwon et al.   Biomedical Materials

High Cup Angle and Microseparation Increase the Wear of Hip Surface Replacements

(2009) Ian J. Leslie et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Nanoparticles can cause DNA damage across a cellular barrier

(2009) Gevdeep Bhabra et al.   Nature Nanotechnology

Presence of corrosion products and hypersensitivity-associated reactions in periprosthetic tissue after aseptic loosening of total hip replacements with metal bearing surfaces

(2008) M HUBER et al.   Acta Biomaterialia

Clicking and Squeaking: In Vivo Correlation of Sound and Separation for Different Bearing Surfaces

(2008) Diana Glaser et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Characterization of the Running-in Period in Total Hip Resurfacing Arthroplasty: An in Vivo and in Vitro Metal Ion Analysis

(2008) Christian Heisel et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Tribology and Wear of Metal-on-Metal Hip Prostheses: Influence of Cup Angle and Head Position

(2008) Sophie Williams et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Modes of Implant Failure After Hip Resurfacing: Morphological and Wear Analysis of 267 Retrieval Specimens

(2008) Michael M Morlock et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Correlation between inclination of the acetabular component and metal ion levels in metal-on-metal hip resurfacing replacement

(2008) R. De Haan et al.   JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME