Adjacent channelrhodopsin-2 residues within transmembranes 2 and 7 regulate cation selectivity and distribution of the two open states

Light and pH-induced Changes in Structure and Accessibility of Transmembrane Helix B and Its Immediate Environment in Channelrhodopsin-2

(2016) Pierre Volz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cysteine Substitution and Labeling Provide Insight into Channelrhodopsin-2 Ion Conductance

(2015) Ryan Richards et al.   BIOCHEMISTRY

Temporal evolution of helix hydration in a light-gated ion channel correlates with ion conductance

(2015) Víctor A. Lórenz-Fonfría et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Dynamics of Channelrhodopsin at the Early Stages of Channel Opening

(2015) Mizuki Takemoto et al.   PLoS One

Independent optical excitation of distinct neural populations

(2014) Nathan C Klapoetke et al.   NATURE METHODS

Conversion of Channelrhodopsin into a Light-Gated Chloride Channel

(2014) J. Wietek et al.   SCIENCE

Light-Induced Movement of the Transmembrane Helix B in Channelrhodopsin-2

(2013) Thomas Sattig et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transmembrane Domain Three Contributes to the Ion Conductance Pathway of Channelrhodopsin-2

(2013) Olga Gaiko et al.   BIOPHYSICAL JOURNAL

Ion Selectivity and Competition in Channelrhodopsins

(2013) Franziska Schneider et al.   BIOPHYSICAL JOURNAL

Computational Modeling of Channelrhodopsin-2 Photocurrent Characteristics in Relation to Neural Signaling

(2013) Roxana A. Stefanescu et al.   BULLETIN OF MATHEMATICAL BIOLOGY

Towards an Understanding of Channelrhodopsin Function: Simulations Lead to Novel Insights of the Channel Mechanism

(2013) Hiroshi C. Watanabe et al.   JOURNAL OF MOLECULAR BIOLOGY

Transient protonation changes in channelrhodopsin-2 and their relevance to channel gating

(2013) V. A. Lorenz-Fonfria et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computational Optogenetics: Empirically-Derived Voltage- and Light-Sensitive Channelrhodopsin-2 Model

(2013) John C. Williams et al.   PLoS Computational Biology

Kinetics of proton release and uptake by channelrhodopsin-2

(2012) Melanie Nack et al.   FEBS LETTERS

Structural Model of Channelrhodopsin

(2012) Hiroshi C. Watanabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In Channelrhodopsin-2 Glu-90 Is Crucial for Ion Selectivity and Is Deprotonated during the Photocycle

(2012) Kirstin Eisenhauer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of the channelrhodopsin light-gated cation channel

(2012) Hideaki E. Kato et al.   NATURE

Re-Introduction of Transmembrane Serine Residues Reduce the Minimum Pore Diameter of Channelrhodopsin-2

(2012) Ryan Richards et al.   PLoS One

Water transport in human aquaporin-4: Molecular dynamics (MD) simulations

(2011) Yubao Cui et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Glutamate residue 90 in the predicted transmembrane domain 2 is crucial for cation flux through channelrhodopsin 2

(2011) Karelia Ruffert et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ultra light-sensitive and fast neuronal activation with the Ca2+-permeable channelrhodopsin CatCh

(2011) Sonja Kleinlogel et al.   NATURE NEUROSCIENCE

Graphical analysis of pH-dependent properties of proteins predicted using PROPKA

(2011) Michał Rostkowski et al.   BMC STRUCTURAL BIOLOGY

Two Open States with Progressive Proton Selectivities in the Branched Channelrhodopsin-2 Photocycle

(2010) André Berndt et al.   BIOPHYSICAL JOURNAL

Evolution of the Channelrhodopsin Photocycle Model

(2010) Katja Stehfest et al.   CHEMPHYSCHEM

Ion permeation simulations by Gromacs-an example of high performance molecular dynamics

(2010) J. Krüger et al.   CONCURRENCY AND COMPUTATION-PRACTICE & EXPERIENCE

Control of neural synchrony using channelrhodopsin-2: a computational study

(2010) Sachin S. Talathi et al.   JOURNAL OF COMPUTATIONAL NEUROSCIENCE

The Branched Photocycle of the Slow-Cycling Channelrhodopsin-2 Mutant C128T

(2010) Katja Stehfest et al.   JOURNAL OF MOLECULAR BIOLOGY

Ultrafast optogenetic control

(2010) Lisa A Gunaydin et al.   NATURE NEUROSCIENCE

Structural Guidance of the Photocycle of Channelrhodopsin-2 by an Interhelical Hydrogen Bond

(2009) Christian Bamann et al.   BIOCHEMISTRY

Conformational Changes of Channelrhodopsin-2

(2009) Ionela Radu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bi-stable neural state switches

(2009) André Berndt et al.   NATURE NEUROSCIENCE

Photocycles of Channelrhodopsin-2

(2009) Konstantin Nikolic et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Channelrhodopsin-2 is a leaky proton pump

(2009) K. Feldbauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Monitoring Light-induced Structural Changes of Channelrhodopsin-2 by UV-visible and Fourier Transform Infrared Spectroscopy

(2008) Eglof Ritter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mechanism of a Neurotransmitter:Sodium Symporter—Inward Release of Na+ and Substrate Is Triggered by Substrate in a Second Binding Site

(2008) Lei Shi et al.   MOLECULAR CELL