Autoinhibition of the Nuclease ARTEMIS Is Mediated by a Physical Interaction between Its Catalytic and C-terminal Domains

Structure-Specific nuclease activities of Artemis and the Artemis: DNA-PKcs complex

(2016) Howard H.Y. Chang et al.   NUCLEIC ACIDS RESEARCH

Lymphopoiesis in transgenic mice over-expressing Artemis

(2015) P Rivera-Munoz et al.   GENE THERAPY

PIKKs — the solenoid nest where partners and kinases meet

(2014) Domagoj Baretić et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The spatial organization of non-homologous end joining: From bridging to end joining

(2014) Takashi Ochi et al.   DNA REPAIR

PTIP associates with Artemis to dictate DNA repair pathway choice

(2014) Jiadong Wang et al.   GENES & DEVELOPMENT

Evidence That the DNA Endonuclease ARTEMIS also Has Intrinsic 5′-Exonuclease Activity

(2014) Sicong Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wiskott-Aldrich syndrome: a comprehensive review

(2013) Michel J. Massaad et al.   Annals of the New York Academy of Sciences

DNA repair genes are selectively mutated in diffuse large B cell lymphomas

(2013) Noel FCC de Miranda et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Structure of the Catalytic Region of DNA Ligase IV in Complex with an Artemis Fragment Sheds Light on Double-Strand Break Repair

(2013) Takashi Ochi et al.   STRUCTURE

DNA repair: the link between primary immunodeficiency and cancer

(2012) Noel FCC de Miranda et al.   Annals of the New York Academy of Sciences

Artemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-PKcs

(2012) Shruti Malu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Targeting DNA repair mechanisms in cancer

(2012) John M. Furgason et al.   PHARMACOLOGY & THERAPEUTICS

Structural Basis of DNA Ligase IV-Artemis Interaction in Nonhomologous End-Joining

(2012) Pablo De Ioannes et al.   Cell Reports

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

An Artemis polymorphic variant reduces Artemis activity and confers cellular radiosensitivity

(2010) Lisa Woodbine et al.   DNA REPAIR

A hypomorphic Artemis human disease allele causes aberrant chromosomal rearrangements and tumorigenesis

(2010) Cheryl Jacobs et al.   HUMAN MOLECULAR GENETICS

The most frequentDCLRE1C(ARTEMIS) mutations are based on homologous recombination events

(2009) Ulrich Pannicke et al.   HUMAN MUTATION

Impact of a hypomorphic Artemis disease allele on lymphocyte development, DNA end processing, and genome stability

(2009) Ying Huang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A DNA-PKcs mutation in a radiosensitive T–B– SCID patient inhibits Artemis activation and nonhomologous end-joining

(2008) Mirjam van der Burg et al.   JOURNAL OF CLINICAL INVESTIGATION

Restoration of Human B-cell Differentiation Into NOD-SCID Mice Engrafted With Gene-corrected CD34+ Cells Isolated From Artemis or RAG1-deficient Patients

(2008) Chantal Lagresle-Peyrou et al.   MOLECULAR THERAPY