Estrogen receptor β–dependent Notch1 activation protects vascular endothelium against tumor necrosis factor α (TNFα)-induced apoptosis

Thirty Years of Saying NO

(2016) Paul M. Vanhoutte et al.   CIRCULATION RESEARCH

Notch1 signalling regulates endothelial proliferation and apoptosis in pulmonary arterial hypertension

(2016) Swati Dabral et al.   EUROPEAN RESPIRATORY JOURNAL

Serum From Advanced Heart Failure Patients Promotes Angiogenic Sprouting and Affects the Notch Pathway in Human Endothelial Cells

(2016) Micaela Pannella et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Endothelial Jagged1 Antagonizes Dll4 Regulation of Endothelial Branching and Promotes Vascular Maturation Downstream of Dll4/Notch1

(2015) A.-R. Pedrosa et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Activation Function-1 of Estrogen Receptor Alpha Prevents Arterial Neointima Development Through a Direct Effect on Smooth Muscle CellsNovelty and Significance

(2015) Natalia F. Smirnova et al.   CIRCULATION RESEARCH

Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis

(2015) Anaïs Briot et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Targeting Notch, Hedgehog and Wnt pathways in cancer stem cells: clinical update

(2015) Naoko Takebe et al.   Nature Reviews Clinical Oncology

CardioPulse

(2014)   EUROPEAN HEART JOURNAL

Endothelial estrogen receptor isoforms and cardiovascular disease

(2014) Kyung Hee Kim et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Notch signal integration in the vasculature during remodeling

(2014) Bahman Rostama et al.   VASCULAR PHARMACOLOGY

Notch inhibitors for cancer treatment

(2013) Ingrid Espinoza et al.   PHARMACOLOGY & THERAPEUTICS

17β-Estradiol Enhances Signalling Mediated by VEGF-A-Delta-Like Ligand 4-Notch1 Axis in Human Endothelial Cells

(2013) Cristiana Caliceti et al.   PLoS One

Testosterone-derived estradiol production by male endothelium is robust and dependent on p450 aromatase via estrogen receptor alpha

(2013) Amparo C Villablanca et al.   SpringerPlus

The Notch pathway: a crossroad between the life and death of the endothelium

(2012) Paola Rizzo et al.   EUROPEAN HEART JOURNAL

The Notch signalling system: recent insights into the complexity of a conserved pathway

(2012) K. G. Guruharsha et al.   NATURE REVIEWS GENETICS

Effects of Celastrol on growth inhibition of U937 leukemia cells through the regulation of the Notch1/NF-kappa B signaling pathway in vitro

(2012) Xiao-Nan Wang et al.   Chinese Journal of Cancer

Estrogen Signaling and Cardiovascular Disease

(2011) Elizabeth Murphy   CIRCULATION RESEARCH

From endothelial dysfunction to atherosclerosis

(2010) S. Sitia et al.   AUTOIMMUNITY REVIEWS

Inflammation dysregulates Notch signaling in endothelial cells: Implication of Notch2 and Notch4 to endothelial dysfunction

(2010) Thibaut Quillard et al.   BIOCHEMICAL PHARMACOLOGY

Estrogen Receptors: Therapies Targeted to Receptor Subtypes

(2010) S Nilsson et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Estrogen, hormonal replacement therapy and cardiovascular disease

(2010) Xiao-Ping Yang et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Notch-1 Inhibition by Withaferin-A: A Therapeutic Target against Colon Carcinogenesis

(2010) S. Koduru et al.   MOLECULAR CANCER THERAPEUTICS

Notch-activated signaling cascade interacts with mitochondrial remodeling proteins to regulate cell survival

(2010) L. R. Perumalsamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Notch Ligands Dll4 and Jagged1 Have Opposing Effects on Angiogenesis

(2009) Rui Benedito et al.   CELL

A hierarchical cascade activated by non-canonical Notch signaling and the mTOR–Rictor complex regulates neglect-induced death in mammalian cells

(2009) L R Perumalsamy et al.   CELL DEATH AND DIFFERENTIATION

Endothelial Estrogen Receptor-α Plays a Crucial Role in the Atheroprotective Action of 17β-Estradiol in Low-Density Lipoprotein Receptor–Deficient Mice

(2009) Audrey Billon-Galés et al.   CIRCULATION

Estradiol Stimulates Vasodilatory and Metabolic Pathways in Cultured Human Endothelial Cells

(2009) Agua Sobrino et al.   PLoS One

Notch2 Signaling Sensitizes Endothelial Cells to Apoptosis by Negatively Regulating the Key Protective Molecule Survivin

(2009) Thibaut Quillard et al.   PLoS One

17β-Estradiol Prevents Early-Stage Atherosclerosis in Estrogen Receptor-Alpha Deficient Female Mice

(2009) Amparo C. Villablanca et al.   Journal of Cardiovascular Translational Research

Impaired Notch4 Activity Elicits Endothelial Cell Activation and Apoptosis

(2008) T. Quillard et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

TNF primes endothelial cells for angiogenic sprouting by inducing a tip cell phenotype

(2008) R. C. A. Sainson et al.   BLOOD

Loss of Notch signalling induced by Dll4 causes arterial calibre reduction by increasing endothelial cell response to angiogenic stimuli

(2008) Rui Benedito et al.   BMC DEVELOPMENTAL BIOLOGY

Cross-talk between Notch and the Estrogen Receptor in Breast Cancer Suggests Novel Therapeutic Approaches

(2008) P. Rizzo et al.   CANCER RESEARCH

Rational targeting of Notch signaling in cancer

(2008) P Rizzo et al.   ONCOGENE

Estrogen decreases TNF-α and oxidized LDL induced apoptosis in endothelial cells

(2007) M. Florian et al.   STEROIDS