The palmitoyltransferase ZDHHC20 enhances interferon-induced transmembrane protein 3 (IFITM3) palmitoylation and antiviral activity

Natural mutations in IFITM3 modulate post‐translational regulation and toggle antiviral specificity

(2016) Alex A Compton et al.   EMBO REPORTS

Activity-Dependent Palmitoylation Controls SynDIG1 Stability, Localization, and Function

(2016) I. Kaur et al.   JOURNAL OF NEUROSCIENCE

The Interferon-Stimulated Gene IFITM3 Restricts Infection and Pathogenesis of Arthritogenic and Encephalitic Alphaviruses

(2016) Subhajit Poddar et al.   JOURNAL OF VIROLOGY

The Interferon-Stimulated GeneIfitm3Restricts West Nile Virus Infection and Pathogenesis

(2016) Matthew J. Gorman et al.   JOURNAL OF VIROLOGY

Inhibition of DHHC20-Mediated EGFR Palmitoylation Creates a Dependence on EGFR Signaling

(2016) Kristin B. Runkle et al.   MOLECULAR CELL

Mass-tag labeling reveals site-specific and endogenous levels of protein S-fatty acylation

(2016) Avital Percher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Model-Driven Understanding of Palmitoylation Dynamics: Regulated Acylation of the Endoplasmic Reticulum Chaperone Calnexin

(2016) Tiziano Dallavilla et al.   PLoS Computational Biology

Interferon-induced transmembrane protein-3 rs12252-C is associated with rapid progression of acute HIV-1 infection in Chinese MSM cohort

(2015) Yonghong Zhang et al.   AIDS

IFITM3 rs12252 T>C polymorphism is associated with the risk of severe influenza: a meta-analysis

(2015) Y. XUAN et al.   EPIDEMIOLOGY AND INFECTION

The Interferon-induced Transmembrane Proteins, IFITM1, IFITM2, and IFITM3 Inhibit Hepatitis C Virus Entry

(2015) Sumudu K. Narayana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IFITMs from Mycobacteria Confer Resistance to Influenza Virus When Expressed in Human Cells

(2015) William Melvin et al.   Viruses-Basel

E3 Ubiquitin Ligase NEDD4 Promotes Influenza Virus Infection by Decreasing Levels of the Antiviral Protein IFITM3

(2015) Nicholas M. Chesarino et al.   PLoS Pathogens

Chemoproteomics reveals Toll-like receptor fatty acylation

(2014) Nicholas M Chesarino et al.   BMC BIOLOGY

Regulation of the trafficking and antiviral activity of IFITM3 by post-translational modifications

(2014) Nicholas M Chesarino et al.   Future Microbiology

Phosphorylation of the Antiviral Protein Interferon-inducible Transmembrane Protein 3 (IFITM3) Dually Regulates Its Endocytosis and Ubiquitination

(2014) Nicholas M. Chesarino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IFITM3 Restricts Influenza A Virus Entry by Blocking the Formation of Fusion Pores following Virus-Endosome Hemifusion

(2014) Tanay M. Desai et al.   PLoS Pathogens

Mechanism and function of DHHC S-acyltransferases: Figure 1

(2013) Maurine E. Linder et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Emerging roles for protein S-palmitoylation in immunity from chemical proteomics

(2013) Jacob S Yount et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

What does S-palmitoylation do to membrane proteins?

(2013) Sanja Blaskovic et al.   FEBS Journal

Negative Regulation of Interferon-induced Transmembrane Protein 3 by SET7-mediated Lysine Monomethylation

(2013) Zhao Shan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Palmitoylation is the switch that assigns calnexin to quality control or ER Ca2+ signaling

(2013) E. M. Lynes et al.   JOURNAL OF CELL SCIENCE

Palmitoylation on Conserved and Nonconserved Cysteines of Murine IFITM1 Regulates Its Stability and Anti-Influenza A Virus Activity

(2013) J. C. Hach et al.   JOURNAL OF VIROLOGY

Role of S-Palmitoylation on IFITM5 for the Interaction with FKBP11 in Osteoblast Cells

(2013) Takashi Tsukamoto et al.   PLoS One

Early hypercytokinemia is associated with interferon-induced transmembrane protein-3 dysfunction and predictive of fatal H7N9 infection

(2013) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amphotericin B Increases Influenza A Virus Infection by Preventing IFITM3-Mediated Restriction

(2013) Tsai-Yu Lin et al.   Cell Reports

IFITM Proteins Restrict Viral Membrane Hemifusion

(2013) Kun Li et al.   PLoS Pathogens

Palmitoylated calnexin is a key component of the ribosome-translocon complex

(2012) Asvin KK Lakkaraju et al.   EMBO JOURNAL

S-Palmitoylation and Ubiquitination Differentially Regulate Interferon-induced Transmembrane Protein 3 (IFITM3)-mediated Resistance to Influenza Virus

(2012) Jacob S. Yount et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The N-Terminal Region of IFITM3 Modulates Its Antiviral Activity by Regulating IFITM3 Cellular Localization

(2012) R. Jia et al.   JOURNAL OF VIROLOGY

IFITM3 restricts the morbidity and mortality associated with influenza

(2012) Aaron R. Everitt et al.   NATURE

The Dispanins: A Novel Gene Family of Ancient Origin That Contains 14 Human Members

(2012) Markus Sällman Almén et al.   PLoS One

Ifitm3 Limits the Severity of Acute Influenza in Mice

(2012) Charles C. Bailey et al.   PLoS Pathogens

Bioorthogonal proteomics of 15-hexadecynyloxyacetic acid chemical reporter reveals preferential targeting of fatty acid modified proteins and biosynthetic enzymes

(2011) Jacob S. Yount et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Human DHHC proteins: A spotlight on the hidden player of palmitoylation

(2011) Justyna Korycka et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

DHHC-7 and -21 are palmitoylacyltransferases for sex steroid receptors

(2011) Ali Pedram et al.   MOLECULAR BIOLOGY OF THE CELL

Regulating the regulator: post-translational modification of RAS

(2011) Ian M. Ahearn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

DHHC palmitoyl transferases: substrate interactions and (patho)physiology

(2011) Jennifer Greaves et al.   TRENDS IN BIOCHEMICAL SCIENCES

Unique Type I Interferon Responses Determine the Functional Fate of Migratory Lung Dendritic Cells during Influenza Virus Infection

(2011) Bruno Moltedo et al.   PLoS Pathogens

IFITM3 Inhibits Influenza A Virus Infection by Preventing Cytosolic Entry

(2011) Eric M. Feeley et al.   PLoS Pathogens

Alkynyl-farnesol reporters for detection ofproteinS-prenylation in cells

(2010) Guillaume Charron et al.   Molecular BioSystems

Palmitoylome profiling reveals S-palmitoylation–dependent antiviral activity of IFITM3

(2010) Jacob S Yount et al.   Nature Chemical Biology

The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus

(2009) Abraham L. Brass et al.   CELL

Neuronal palmitoyl acyl transferases exhibit distinct substrate specificity

(2009) Kun Huang et al.   FASEB JOURNAL

Robust Fluorescent Detection of Protein Fatty-Acylation with Chemical Reporters

(2009) Guillaume Charron et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Identification of G Protein   Subunit-Palmitoylating Enzyme

(2008) R. Tsutsumi et al.   MOLECULAR AND CELLULAR BIOLOGY

DHHC2 Affects Palmitoylation, Stability, and Functions of Tetraspanins CD9 and CD151

(2008) Chandan Sharma et al.   MOLECULAR BIOLOGY OF THE CELL

Widespread conservation of genetic redundancy during a billion years of eukaryotic evolution

(2008) Tanya Vavouri et al.   TRENDS IN GENETICS