Interleukin 27 (IL-27) Alleviates Bone Loss in Estrogen-deficient Conditions by Induction of Early Growth Response-2 Gene

IL-18BP is decreased in osteoporotic women: Prevents Inflammasome mediated IL-18 activation and reduces Th17 differentiation

(2016) Mohd Nizam Mansoori et al.   Scientific Reports

Parathyroid hormone: anabolic and catabolic actions on the skeleton

(2015) Barbara C Silva et al.   CURRENT OPINION IN PHARMACOLOGY

TGF-β3-expressing CD4+CD25−LAG3+ regulatory T cells control humoral immune responses

(2015) Tomohisa Okamura et al.   Nature Communications

Bone Loss Triggered by the Cytokine Network in Inflammatory Autoimmune Diseases

(2015) Dulshara Sachini Amarasekara et al.   Journal of Immunology Research

Enhanced Immunoprotective Effects by Anti-IL-17 Antibody Translates to Improved Skeletal Parameters Under Estrogen Deficiency Compared With Anti-RANKL and Anti-TNF-α Antibodies

(2014) Abdul M Tyagi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

IL-27 paves different roads to Tr1

(2013) Ajithkumar Vasanthakumar et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Epidermal Growth Factor Receptor (EGFR) Signaling Promotes Proliferation and Survival in Osteoprogenitors by Increasing Early Growth Response 2 (EGR2) Expression

(2013) Abhishek Chandra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of inflammation by interleukin-27

(2013) Markus Bosmann et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Early growth response 2 negatively modulates osteoclast differentiation through upregulation of Id helix–loop–helix proteins

(2012) Hyun-Ju Kim et al.   BONE

The emerging role of Interleukin 27 in inflammatory arthritis and bone destruction

(2012) Iannis E. Adamopoulos et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Interleukin-27: Balancing Protective and Pathological Immunity

(2012) Christopher A. Hunter et al.   IMMUNITY

The Transcription Factors Egr2 and Egr3 Are Essential for the Control of Inflammation and Antigen-Induced Proliferation of B and T Cells

(2012) Suling Li et al.   IMMUNITY

Interleukin-27 suppresses osteoclastogenesis via induction of interferon-γ

(2012) Jin-Sil Park et al.   IMMUNOLOGY

Interleukin-6 induces the generation of IL-10-producing Tr1 cells and suppresses autoimmune tissue inflammation

(2012) Jun-O Jin et al.   JOURNAL OF AUTOIMMUNITY

IL-12 family cytokines: immunological playmakers

(2012) Dario A A Vignali et al.   NATURE IMMUNOLOGY

Estrogen Deficiency Induces the Differentiation of IL-17 Secreting Th17 Cells: A New Candidate in the Pathogenesis of Osteoporosis

(2012) Abdul M. Tyagi et al.   PLoS One

Disorders of Bone Remodeling

(2011) Xu Feng et al.   Annual Review of Pathology-Mechanisms of Disease

Interleukin-27-Mediated Suppression of Human Th17 Cells Is Associated with Activation of STAT1 and Suppressor of Cytokine Signaling Protein 1

(2011) Hong Liu et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Premature T cell senescence in Ovx mice is inhibited by repletion of estrogen and medicarpin: a possible mechanism for alleviating bone loss

(2011) A. M. Tyagi et al.   OSTEOPOROSIS INTERNATIONAL

Induction of regulatory Tr1 cells and inhibition of TH17 cells by IL-27

(2011) Caroline Pot et al.   SEMINARS IN IMMUNOLOGY

IL-27 inhibits human osteoclastogenesis by abrogating RANKL-mediated induction of NFATc1 and suppressing proximal RANK signaling

(2010) George D. Kalliolias et al.   ARTHRITIS AND RHEUMATISM

Medicarpin inhibits osteoclastogenesis and has nonestrogenic bone conserving effect in ovariectomized mice

(2010) Abdul M. Tyagi et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

IL-27 Is a Key Regulator of IL-10 and IL-17 Production by Human CD4+ T Cells

(2009) G. Murugaiyan et al.   JOURNAL OF IMMUNOLOGY

Osteoimmunology and the effects of the immune system on bone

(2009) Hiroshi Takayanagi   Nature Reviews Rheumatology