Transcriptome analysis reveals determinant stages controlling human embryonic stem cell commitment to neuronal cells

Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice

(2017) Jordano Brito-Moreira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spatial transcriptomic analysis of cryosectioned tissue samples with Geo-seq

(2017) Jun Chen et al.   Nature Protocols

Heterotopic Transcallosal Projections Are Present throughout the Mouse Cortex

(2017) Alexandra Chovsepian et al.   Frontiers in Cellular Neuroscience

A quantitative brain map of experimental cerebral malaria pathology

(2017) Patrick Strangward et al.   PLoS Pathogens

Expression of Barhl2 and its relationship with Pax6 expression in the forebrain of the mouse embryo

(2016) Elisa V. Parish et al.   BMC NEUROSCIENCE

Spatial Transcriptome for the Molecular Annotation of Lineage Fates and Cell Identity in Mid-gastrula Mouse Embryo

(2016) Guangdun Peng et al.   DEVELOPMENTAL CELL

A Novel and Multivalent Role of Pax6 in Cerebellar Development

(2016) J. Yeung et al.   JOURNAL OF NEUROSCIENCE

Time-Course Gene Expression Profiling Reveals a Novel Role of Non-Canonical WNT Signaling During Neural Induction

(2016) Cindy Tzu-Ling Huang et al.   Scientific Reports

Single-Cell Transcriptome Analyses Reveal Signals to Activate Dormant Neural Stem Cells

(2015) Yuping Luo et al.   CELL

Deterministic HOX Patterning in Human Pluripotent Stem Cell-Derived Neuroectoderm

(2015) Ethan S. Lippmann et al.   Stem Cell Reports

MiR-135b is a direct PAX6 target and specifies human neuroectoderm by inhibiting TGF- /BMP signaling

(2014) A. Bhinge et al.   EMBO JOURNAL

Transcriptional landscape of the prenatal human brain

(2014) Jeremy A. Miller et al.   NATURE

Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq

(2014) Barbara Treutlein et al.   NATURE

The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification

(2014) Thorsten Boroviak et al.   NATURE CELL BIOLOGY

CORTECON: A Temporal Transcriptome Analysis of In Vitro Human Cerebral Cortex Development from Human Embryonic Stem Cells

(2014) Joyce van de Leemput et al.   NEURON

The transcription factor Pou3f1 promotes neural fate commitment via activation of neural lineage genes and inhibition of external signaling pathways

(2014) Qingqing Zhu et al.   eLife

Correction of a Genetic Disease in Mouse via Use of CRISPR-Cas9

(2013) Yuxuan Wu et al.   Cell Stem Cell

Location of transient ectodermal progenitor potential in mouse development

(2013) L. Li et al.   DEVELOPMENT

Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing

(2013) Zhigang Xue et al.   NATURE

Using networks to measure similarity between genes: association index selection

(2013) Juan I Fuxman Bass et al.   NATURE METHODS

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Six3 cooperates with Hedgehog signaling to specify ventral telencephalon by promoting early expression of Foxg1a and repressing Wnt signaling

(2012) D. Carlin et al.   DEVELOPMENT

Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses

(2012) Yichen Shi et al.   NATURE NEUROSCIENCE

Neural induction and early patterning in vertebrates

(2012) Mohammad Zeeshan Ozair et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Clonal and molecular analysis of the prospective anterior neural boundary in the mouse embryo

(2011) M. Cajal et al.   DEVELOPMENT

Spatio-temporal transcriptome of the human brain

(2011) Hyo Jung Kang et al.   NATURE

Intrinsic transition of embryonic stem-cell differentiation into neural progenitors

(2011) Daisuke Kamiya et al.   NATURE

Investigating synapse formation and function using human pluripotent stem cell-derived neurons

(2011) J.-E. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fibroblast Growth Factor Regulates Human Neuroectoderm Specification Through ERK1/2-PARP-1 Pathway

(2011) Young Dong Yoo et al.   STEM CELLS

The Controlled Generation of Functional Basal Forebrain Cholinergic Neurons from Human Embryonic Stem Cells

(2011) Christopher J. Bissonnette et al.   STEM CELLS

Pax6 Is a Human Neuroectoderm Cell Fate Determinant

(2010) Xiaoqing Zhang et al.   Cell Stem Cell

Heterozygous mutations in SIX3 and SHH are associated with schizencephaly and further expand the clinical spectrum of holoprosencephaly

(2010) Ute Hehr et al.   HUMAN GENETICS

Neuroretina specification in mouse embryos requires Six3-mediated suppression of Wnt8b in the anterior neural plate

(2010) Wei Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Retinoic acid regulates bone morphogenic protein signal duration by promoting the degradation of phosphorylated Smad1

(2010) N. Sheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel SIX3 mutation segregates with holoprosencephaly in a large family

(2009) Benjamin D. Solomon et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Human oligodendrocytes from embryonic stem cells: conserved SHH signaling networks and divergent FGF effects

(2009) B.-Y. Hu et al.   DEVELOPMENT

Clinical spectrum of SIX3-associated mutations in holoprosencephaly: correlation between genotype, phenotype and function

(2009) F Lacbawan et al.   JOURNAL OF MEDICAL GENETICS

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo

(2009) Sebastian J. Arnold et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Evolution of the neocortex: a perspective from developmental biology

(2009) Pasko Rakic   NATURE REVIEWS NEUROSCIENCE

Gradients in the Brain: The Control of the Development of Form and Function in the Cerebral Cortex

(2009) S. N. Sansom et al.   Cold Spring Harbor Perspectives in Biology

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage

(2008) Y. Elkabetz et al.   GENES & DEVELOPMENT

An intrinsic mechanism of corticogenesis from embryonic stem cells

(2008) Nicolas Gaspard et al.   NATURE

Efficient derivation of functional dopaminergic neurons from human embryonic stem cells on a large scale

(2008) Myung-Soo Cho et al.   Nature Protocols