Discoidin domain receptor 2 mediates collagen-induced activation of membrane-type 1 matrix metalloproteinase in human fibroblasts

Type I collagen aging impairs discoidin domain receptor 2-mediated tumor cell growth suppression

(2016) Charles Saby et al.   Oncotarget

Selective Inhibition of Membrane Type 1 Matrix Metalloproteinase Abrogates Progression of Experimental Inflammatory Arthritis: Synergy With Tumor Necrosis Factor Blockade

(2016) Kazuyo Kaneko et al.   Arthritis & Rheumatology

Membrane-type matrix metalloproteinases: Their functions and regulations

(2015) Yoshifumi Itoh   MATRIX BIOLOGY

Integrin-Linked Kinase links Dynactin-1/Dynactin-2 with cortical Integrin receptors to orient the mitotic spindle relative to the substratum

(2015) Edward James Morris et al.   Scientific Reports

Discoidin domain receptor 1 controls linear invadosome formation via a Cdc42–Tuba pathway

(2014) Amélie Juin et al.   JOURNAL OF CELL BIOLOGY

Discoidin domain receptor 2 (DDR2) promotes breast cancer cell metastasis and the mechanism implicates epithelial-mesenchymal transition programme under hypoxia

(2014) Tingting Ren et al.   JOURNAL OF PATHOLOGY

Discovery of a Potent and Selective DDR1 Receptor Tyrosine Kinase Inhibitor

(2013) Hyung-Gu Kim et al.   ACS Chemical Biology

The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis

(2013) Kun Zhang et al.   NATURE CELL BIOLOGY

Detection of cartilage matrix degradation by autofluorescence lifetime

(2012) Hugh B. Manning et al.   MATRIX BIOLOGY

Transmembrane Collagen Receptors

(2011) Birgit Leitinger   Annual Review of Cell and Developmental Biology

Targeting the Warburg Effect That Arises in Tumor Cells Expressing Membrane Type-1 Matrix Metalloproteinase

(2011) Takeharu Sakamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Membrane Protease Regulates Energy Production in Macrophages by Activating Hypoxia-inducible Factor-1 via a Non-proteolytic Mechanism

(2010) Takeharu Sakamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane-Type I Matrix Metalloproteinase-Dependent Regulation of Rheumatoid Arthritis Synoviocyte Function

(2010) F. Sabeh et al.   JOURNAL OF IMMUNOLOGY

Collagen binding specificity of the discoidin domain receptors: Binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1

(2010) Huifang Xu et al.   MATRIX BIOLOGY

Comparative suppressive effects of tyrosine kinase inhibitors imatinib and nilotinib in models of autoimmune arthritis

(2010) Naotsugu Akashi et al.   Modern Rheumatology

Membrane type 1 matrix metalloproteinase is a crucial promoter of synovial invasion in human rheumatoid arthritis

(2009) Mary-Clare Miller et al.   ARTHRITIS AND RHEUMATISM

Inhibition of Collagen Fibrillogenesis by Cells Expressing Soluble Extracellular Domains of DDR1 and DDR2

(2009) Lisa A. Flynn et al.   JOURNAL OF MOLECULAR BIOLOGY

Tyrosine kinases as targets for the treatment of rheumatoid arthritis

(2009) Christina D'Aura Swanson et al.   Nature Reviews Rheumatology

Crystallographic Insight into Collagen Recognition by Discoidin Domain Receptor 2

(2009) Federico Carafoli et al.   STRUCTURE

Inhibition of collagen-induced discoidin domain receptor 1 and 2 activation by imatinib, nilotinib and dasatinib

(2008) Elizabeth Day et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Characterization of High Affinity Binding Motifs for the Discoidin Domain Receptor DDR2 in Collagen

(2008) Antonios D. Konitsiotis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The N-Terminal Domain of Nogo-A Inhibits Cell Adhesion and Axonal Outgrowth by an Integrin-Specific Mechanism

(2008) F. Hu et al.   JOURNAL OF NEUROSCIENCE