Discovery of a widespread prokaryotic 5-oxoprolinase that was hiding in plain sight

Non-enzymatic molecular damage as a prototypic driver of aging

(2017) Alexey Golubev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lynn Margulis and the endosymbiont hypothesis: 50 years later

(2017) Michael W. Gray   MOLECULAR BIOLOGY OF THE CELL

Nit1 is a metabolite repair enzyme that hydrolyzes deaminated glutathione

(2017) Alessio Peracchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Construction and Analysis of Two Genome-Scale Deletion Libraries for Bacillus subtilis

(2017) Byoung-Mo Koo et al.   Cell Systems

Unravelling 5-oxoprolinuria (pyroglutamic aciduria) due to bi-allelic OPLAH mutations: 20 new mutations in 14 families

(2016) Jörn Oliver Sass et al.   MOLECULAR GENETICS AND METABOLISM

The urea carboxylase and allophanate hydrolase activities of urea amidolyase are functionally independent

(2016) Yi Lin et al.   PROTEIN SCIENCE

Acinetobacter baumannii Coordinates Urea Metabolism with Metal Import To Resist Host-Mediated Metal Limitation

(2016) Lillian J. Juttukonda et al.   mBio

Genomic and experimental evidence for multiple metabolic functions in the RidA/YjgF/YER057c/UK114 (Rid) protein family

(2015) Thomas D Niehaus et al.   BMC GENOMICS

Monitoring bacterial growth using tunable resistive pulse sensing with a pore-based technique

(2013) Allen C. S. Yu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A  -Glutamyl Cyclotransferase Protects Arabidopsis Plants from Heavy Metal Toxicity by Recycling Glutamate to Maintain Glutathione Homeostasis

(2013) B. Paulose et al.   PLANT CELL

The structure of TTHA0988 fromThermus thermophilus, a KipI–KipA homologue incorrectly annotated as an allophanate hydrolase

(2011) David A. Jacques et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

prhKLM genes of Ralstonia solanacearum encode novel activators of hrp regulon and are required for pathogenesis in tomato

(2011) Yong Zhang et al.   FEMS MICROBIOLOGY LETTERS

Extremely Conserved ATP- or ADP-dependent Enzymatic System for Nicotinamide Nucleotide Repair

(2011) Alexandre Y. Marbaix et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conserved YjgF Protein Family Deaminates Reactive Enamine/Imine Intermediates of Pyridoxal 5′-Phosphate (PLP)-dependent Enzyme Reactions

(2011) Jennifer A. Lambrecht et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kinetic and structural characterization of bacterial glutaminyl cyclases from Zymomonas mobilis and Myxococcus xanthus

(2010) David Ruiz Carrillo et al.   BIOLOGICAL CHEMISTRY

OXP1/YKL215c encodes an ATP-dependent 5-oxoprolinase in Saccharomyces cerevisiae: functional characterization, domain structure and identification of actin-like ATP-binding motifs in eukaryotic 5-oxoprolinases

(2010) Akhilesh Kumar et al.   FEMS YEAST RESEARCH

A Novel Structure of an Antikinase and its Inhibitor

(2010) David A. Jacques et al.   JOURNAL OF MOLECULAR BIOLOGY

‘Unknown’ proteins and ‘orphan’ enzymes: the missing half of the engineering parts list – and how to find it

(2009) Andrew D. Hanson et al.   BIOCHEMICAL JOURNAL

Bacillithiol is an antioxidant thiol produced in Bacilli

(2009) Gerald L Newton et al.   Nature Chemical Biology

Glutaminyl cyclases from animals and plants: a case of functionally convergent protein evolution

(2008) Stephan Schilling et al.   BIOLOGICAL CHEMISTRY

A  -Glutamyl Transpeptidase-Independent Pathway of Glutathione Catabolism to Glutamate via 5-Oxoproline in Arabidopsis

(2008) N. Ohkama-Ohtsu et al.   PLANT PHYSIOLOGY