A Trimer Consisting of the Tubulin-specific Chaperone D (TBCD), Regulatory GTPase ARL2, and β-Tubulin Is Required for Maintaining the Microtubule Network

Biallelic Mutations in TBCD , Encoding the Tubulin Folding Cofactor D, Perturb Microtubule Dynamics and Cause Early-Onset Encephalopathy

(2016) Elisabetta Flex et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Biallelic TBCD Mutations Cause Early-Onset Neurodegenerative Encephalopathy

(2016) Noriko Miyake et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Microcephaly, intractable seizures and developmental delay caused by biallelic variants inTBCD: further delineation of a new chaperone-mediated tubulinopathy

(2016) B. Pode-Shakked et al.   CLINICAL GENETICS

Tubulin Dimer Reversible Dissociation

(2016) Felipe Montecinos-Franjola et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arl2- and Msps-dependent microtubule growth governs asymmetric division

(2016) Keng Chen et al.   JOURNAL OF CELL BIOLOGY

TBCD may be a causal gene in progressive neurodegenerative encephalopathy with atypical infantile spinal muscular atrophy

(2016) Toshio Ikeda et al.   JOURNAL OF HUMAN GENETICS

The structure of the complex between  -tubulin, TBCE and TBCB reveals a tubulin dimer dissociation mechanism

(2015) M. Serna et al.   JOURNAL OF CELL SCIENCE

Linking Cell Surface Receptors to Microtubules: Tubulin Folding Cofactor D Mediates Dscam Functions during Neuronal Morphogenesis

(2015) M. Okumura et al.   JOURNAL OF NEUROSCIENCE

Tubulin cofactors and Arl2 are cage-like chaperones that regulate the soluble αβ-tubulin pool for microtubule dynamics

(2015) Stanley Nithianantham et al.   eLife

Effect of TBCD and its regulatory interactor Arl2 on tubulin and microtubule integrity

(2010) Guoling Tian et al.   Cytoskeleton

The small GTPase ARL2 is required for cytokinesis in Trypanosoma brucei

(2010) Helen P. Price et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

TBCD Links Centriologenesis, Spindle Microtubule Dynamics, and Midbody Abscission in Human Cells

(2010) Mónica López Fanarraga et al.   PLoS One

Crystal Structure of the ARL2-GTP-BART Complex Reveals a Novel Recognition and Binding Mode of Small GTPase with Effector

(2009) Tianlong Zhang et al.   STRUCTURE

Cofactor D Functions as a Centrosomal Protein and Is Required for the Recruitment of the γ-Tubulin Ring Complex at Centrosomes and Organization of the Mitotic Spindle

(2008) Leslie A. Cunningham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

β-tubulin cofactor D and ARL2 take part in apical junctional complex disassembly and abrogate epithelial structure

(2007) Tamar Shultz et al.   FASEB JOURNAL