NMR-directed design of pre-TCRβ and pMHC molecules implies a distinct geometry for pre-TCR relative to αβTCR recognition of pMHC

Mechanosensing drives acuity ofαβT-cell recognition

(2017) Yinnian Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MHC Bias by T Cell Receptors: Genetic Evidence for MHC and TCR Coevolution

(2017) Brian M. Baker et al.   TRENDS IN IMMUNOLOGY

An allosteric site in the T-cell receptor Cβ domain plays a critical signalling role

(2017) Kannan Natarajan et al.   Nature Communications

Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation

(2017) Marek Wieczorek et al.   Frontiers in Immunology

Pre-T Cell Receptors (Pre-TCRs) Leverage Vβ Complementarity Determining Regions (CDRs) and Hydrophobic Patch in Mechanosensing Thymic Self-ligands

(2016) Dibyendu Kumar Das et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The HADDOCK2.2 Web Server: User-Friendly Integrative Modeling of Biomolecular Complexes

(2016) G.C.P. van Zundert et al.   JOURNAL OF MOLECULAR BIOLOGY

DNA-based nanoparticle tension sensors reveal that T-cell receptors transmit defined pN forces to their antigens for enhanced fidelity

(2016) Yang Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Backbone resonance assignment of N15, N30 and D10 T cell receptor β subunits

(2015) Robert J. Mallis et al.   Biomolecular NMR Assignments

Pre-TCR ligand binding impacts thymocyte development before αβTCR expression

(2015) Robert J. Mallis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime

(2015) Dibyendu Kumar Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Features of the αβTCR Mechanotransduction Apparatus That Promote pMHC Discrimination

(2015) Kristine N. Brazin et al.   Frontiers in Immunology

Accumulation of Dynamic Catch Bonds between TCR and Agonist Peptide-MHC Triggers T Cell Signaling

(2014) Baoyu Liu et al.   CELL

RASP: rapid and robust backbone chemical shift assignments from protein structure

(2014) Christopher A. MacRaild et al.   JOURNAL OF BIOMOLECULAR NMR

An Overview of the Intrathymic Intricacies of T Cell Development

(2014) D. K. Shah et al.   JOURNAL OF IMMUNOLOGY

Perspectives in magnetic resonance: NMR in the post-FFT era

(2014) Sven G. Hyberts et al.   JOURNAL OF MAGNETIC RESONANCE

Murine thymic selection quantified using a unique method to capture deleted T cells

(2013) G. L. Stritesky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The regulatory power of glycans and their binding partners in immunity

(2013) Jenny L. Johnson et al.   TRENDS IN IMMUNOLOGY

A Closer Look at TCR Germline Recognition

(2012) K. Christopher Garcia et al.   IMMUNITY

αβ T Cell Receptors that Do Not Undergo Major Histocompatibility Complex-Specific Thymic Selection Possess Antibody-like Recognition Specificities

(2011) Anastasia N. Tikhonova et al.   IMMUNITY

A Conserved Hydrophobic Patch on Vβ Domains Revealed by TCRβ Chain Crystal Structures: Implications for Pre-TCR Dimerization

(2011) Bo Zhou et al.   Frontiers in Immunology

SPARTA+: a modest improvement in empirical NMR chemical shift prediction by means of an artificial neural network

(2010) Yang Shen et al.   JOURNAL OF BIOMOLECULAR NMR

The structural basis for autonomous dimerization of the pre-T-cell antigen receptor

(2010) Siew Siew Pang et al.   NATURE

The αβ T Cell Receptor Is an Anisotropic Mechanosensor

(2009) Sun Taek Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CCR7-mediated migration of developing thymocytes to the medulla is essential for negative selection to tissue-restricted antigens

(2009) T. Nitta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA