The mitochondrial outer membrane protein mitoNEET is a redox enzyme catalyzing electron transfer from FMNH2to oxygen or ubiquinone

Flavin nucleotides act as electron shuttles mediating reduction of the [2Fe-2S] clusters in mitochondrial outer membrane protein mitoNEET

(2017) Aaron P. Landry et al.   FREE RADICAL BIOLOGY AND MEDICINE

Phylogenetic analysis of eukaryotic NEET proteins uncovers a link between a key gene duplication event and the evolution of vertebrates

(2017) Madhuri A. Inupakutika et al.   Scientific Reports

CISD1 inhibits ferroptosis by protection against mitochondrial lipid peroxidation

(2016) Hua Yuan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of small molecules that bind to the mitochondrial protein mitoNEET

(2016) Werner J. Geldenhuys et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

MitoNEET-Parkin Effects in Pancreatic α- and β-Cells, Cellular Survival, and Intrainsular Cross Talk

(2016) Christine M. Kusminski et al.   DIABETES

Redox Control of the Human Iron-Sulfur Repair Protein MitoNEET Activity via Its Iron-Sulfur Cluster

(2016) Marie-Pierre Golinelli-Cohen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diabetes treatments and risk of heart failure, cardiovascular disease, and all cause mortality: cohort study in primary care

(2016) Julia Hippisley-Cox et al.   BMJ-British Medical Journal

Diabetes treatments and risk of heart failure, cardiovascular disease, and all cause mortality: cohort study in primary care

(2016) Julia Hippisley-Cox et al.   BMJ-British Medical Journal

MicroRNA-127 targeting of mitoNEET inhibits neurite outgrowth, induces cell apoptosis and contributes to physiological dysfunction after spinal cord transection

(2016) Qin-Qin He et al.   Scientific Reports

Novel thiazolidinedione mitoNEET ligand-1 acutely improves cardiac stem cell survival under oxidative stress

(2015) Suzanna J. Logan et al.   BASIC RESEARCH IN CARDIOLOGY

Biogenesis of cytosolic and nuclear iron–sulfur proteins and their role in genome stability

(2015) Viktoria Désirée Paul et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Structure–function analysis of NEET proteins uncovers their role as key regulators of iron and ROS homeostasis in health and disease

(2015) Sagi Tamir et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Quantification of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in mammalian model cells by CE with LED-induced fluorescence detection

(2015) Jens Hühner et al.   ELECTROPHORESIS

Reduction of mitochondrial protein mitoNEET [2Fe–2S] clusters by human glutathione reductase

(2015) Aaron P. Landry et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cancer-Related NEET Proteins Transfer 2Fe-2S Clusters to Anamorsin, a Protein Required for Cytosolic Iron-Sulfur Cluster Biogenesis

(2015) Colin H. Lipper et al.   PLoS One

The Fe-S cluster-containing NEET proteins mitoNEET and NAF-1 as chemotherapeutic targets in breast cancer

(2015) Fang Bai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Redox Control of Human Mitochondrial Outer Membrane Protein MitoNEET [2Fe-2S] Clusters by Biological Thiols and Hydrogen Peroxide

(2014) Aaron P. Landry et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Minireview: Challenges and Opportunities in Development of PPAR Agonists

(2014) Matthew B. Wright et al.   MOLECULAR ENDOCRINOLOGY

MitoNEET-mediated effects on browning of white adipose tissue

(2014) Christine M. Kusminski et al.   Nature Communications

Identification of Disulfide Bond Formation between MitoNEET and Glutamate Dehydrogenase 1

(2013) Morgan E. Roberts et al.   BIOCHEMISTRY

Crystal structure of the entire respiratory complex I

(2013) Rozbeh Baradaran et al.   NATURE

NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth

(2013) Yang-Sung Sohn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Census of Human Soluble Protein Complexes

(2012) Pierre C. Havugimana et al.   CELL

Mitochondrial biogenesis in epithelial cancer cells promotes breast cancer tumor growth and confers autophagy resistance

(2012) Ahmed F. Salem et al.   CELL CYCLE

The submitochondrial distribution of ubiquinone affects respiration in long-livedMclk1+/−mice

(2012) Jérôme Lapointe et al.   JOURNAL OF CELL BIOLOGY

MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity

(2012) Christine M Kusminski et al.   NATURE MEDICINE

Novel ligands that target the mitochondrial membrane protein mitoNEET

(2011) Robert M. Bieganski et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Structure and Molecular Evolution of CDGSH Iron-Sulfur Domains

(2011) Jinzhong Lin et al.   PLoS One

Facile transfer of [2Fe-2S] clusters from the diabetes drug target mitoNEET to an apo-acceptor protein

(2011) John A. Zuris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular coenzymes as natural biomarkers for metabolic activities and mitochondrial anomalies

(2010) Ahmed A Heikal   Biomarkers in Medicine

Structure-based design of a thiazolidinedione which targets the mitochondrial protein mitoNEET

(2010) Werner J. Geldenhuys et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Thermodynamic and kinetic considerations for the reaction of semiquinone radicals to form superoxide and hydrogen peroxide

(2010) Yang Song et al.   FREE RADICAL BIOLOGY AND MEDICINE

Redox Characterization of the FeS Protein MitoNEET and Impact of Thiazolidinedione Drug Binding

(2009) Daniel W. Bak et al.   BIOCHEMISTRY

Continuous-Wave and Pulsed EPR Characterization of the [2Fe−2S](Cys)3(His)1Cluster in Rat MitoNEET

(2009) Toshio Iwasaki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Computational and experimental studies on the catalytic mechanism of biliverdin-IXβ reductase

(2008) Liam J. Smith et al.   BIOCHEMICAL JOURNAL