The soluble protease ADAMDEC1 released from activated platelets hydrolyzes platelet membrane pro-epidermal growth factor (EGF) to active high-molecular-weight EGF

NETosis Delays Diabetic Wound Healing in Mice and Humans

(2016) Gian Paolo Fadini et al.   DIABETES

Critical Role of the Disintegrin Metalloprotease ADAM-like Decysin-1 [ADAMDEC1] for Intestinal Immunity and Inflammation

(2016) Nuala R. O’Shea et al.   Journal of Crohns & Colitis

Prevalence of soluble peptidylarginine deiminase 4 (PAD4) and anti-PAD4 antibodies in autoimmune diseases

(2015) Naoto Umeda et al.   CLINICAL RHEUMATOLOGY

Evidence for Restricted Reactivity of ADAMDEC1 with Protein Substrates and Endogenous Inhibitors

(2015) Jacob Lund et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular regulation of metalloproteinases

(2015) Kazuhiro Yamamoto et al.   MATRIX BIOLOGY

Diabetes primes neutrophils to undergo NETosis, which impairs wound healing

(2015) Siu Ling Wong et al.   NATURE MEDICINE

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Role of epidermal growth factor receptor in vascular structure and function

(2014) Barbara Schreier et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

LC–MS Based Cleavage Site Profiling of the Proteases ADAM10 and ADAM17 Using Proteome-Derived Peptide Libraries

(2014) Joanna Tucher et al.   JOURNAL OF PROTEOME RESEARCH

High Precision Platelet Releasate Definition by Quantitative Reversed Protein Profiling—Brief Report

(2013) Patrick Wijten et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Peptidylarginine deiminases in citrullination, gene regulation, health and pathogenesis

(2013) Shu Wang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

ADAMDEC1 Is a Metzincin Metalloprotease with Dampened Proteolytic Activity

(2013) Jacob Lund et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipopolysaccharide Stimulates Platelets through an IL-1  Autocrine Loop

(2013) G. T. Brown et al.   JOURNAL OF IMMUNOLOGY

The ErbB/HER family of protein-tyrosine kinases and cancer

(2013) Robert Roskoski   PHARMACOLOGICAL RESEARCH

Growth factor release from platelet concentrates: analytic quantification and characterization for clinical applications

(2013) C. Durante et al.   VOX SANGUINIS

Epidermal Growth Factor and Epidermal Growth Factor Receptor: The Yin and Yang in the Treatment of Cutaneous Wounds and Cancer

(2013) Richard J. Bodnar   Advances in Wound Care

The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways

(2012) J. M. Burkhart et al.   BLOOD

Current role of EGF receptor monoclonal antibodies and tyrosine kinase inhibitors in the management of head and neck squamous cell carcinoma

(2012) Ana Markovic et al.   Expert Review of Anticancer Therapy

Inactivation of Epidermal Growth Factor by Porphyromonas gingivalis as a Potential Mechanism for Periodontal Tissue Damage

(2012) Krzysztof Pyrc et al.   INFECTION AND IMMUNITY

Lipopolysaccharide Signaling without a Nucleus: Kinase Cascades Stimulate Platelet Shedding of Proinflammatory IL-1 -Rich Microparticles

(2011) G. T. Brown et al.   JOURNAL OF IMMUNOLOGY

Epidermal Growth Factor Receptor Expression Identifies Functionally and Molecularly Distinct Tumor-Initiating Cells in Human Glioblastoma Multiforme and Is Required for Gliomagenesis

(2010) S. Mazzoleni et al.   CANCER RESEARCH

Identification of ADAM10 as a major TNF sheddase in ADAM17-deficient fibroblasts

(2009) Renata Mężyk-Kopeć et al.   CYTOKINE

Epidermal growth factor released from platelet-rich plasma promotes endothelial cell proliferationin vitro

(2009) M.-P. Bertrand-Duchesne et al.   JOURNAL OF PERIODONTAL RESEARCH

Effects of epidermal growth factor on the invasion activity of the oral cancer cell lines HSC3 and SAS

(2008) Yuichi Ohnishi et al.   ORAL ONCOLOGY

Quantitative assessment of the kinetics of growth factors release from platelet gel

(2008) Chen Y. Su et al.   TRANSFUSION