Occupancy of the Zinc-binding Site by Transition Metals Decreases the Substrate Affinity of the Human Dopamine Transporter by an Allosteric Mechanism

Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism–dystonia

(2016) Karin Tuschl et al.   Nature Communications

The conservative view: is it necessary to implant a stent into the dopamine transporter?

(2015) D Schmid et al.   BRITISH JOURNAL OF PHARMACOLOGY

Dual Action of Zn2+on the Transport Cycle of the Dopamine Transporter

(2015) Yang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wilson's disease and other neurological copper disorders

(2015) Oliver Bandmann et al.   LANCET NEUROLOGY

Amphetamines, new psychoactive drugs and the monoamine transporter cycle

(2015) Harald H. Sitte et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Zn2+ reverses functional deficits in a de novo dopamine transporter variant associated with autism spectrum disorder

(2015) Peter J Hamilton et al.   Molecular Autism

Dopamine transporter deficiency syndrome: phenotypic spectrum from infancy to adulthood

(2014) Joanne Ng et al.   BRAIN

Metal Preferences and Metallation

(2014) Andrew W. Foster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SLC30A10 Is a Cell Surface-Localized Manganese Efflux Transporter, and Parkinsonism-Causing Mutations Block Its Intracellular Trafficking and Efflux Activity

(2014) D. Leyva-Illades et al.   JOURNAL OF NEUROSCIENCE

A quantitative model of amphetamine action on the 5-HT transporter

(2013) Walter Sandtner et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mutational Analysis of the High-Affinity Zinc Binding Site Validates a Refined Human Dopamine Transporter Homology Model

(2013) Thomas Stockner et al.   PLoS Computational Biology

Resolution of Cranial MRI and SPECT Abnormalities in a Patient with Wilson's Disease Following Oral Zinc Monotherapy

(2012) Shimon Ishida et al.   INTERNAL MEDICINE

Unifying Concept of Serotonin Transporter-associated Currents

(2011) Klaus Schicker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New perspectives of zinc coordination environments in proteins

(2011) Wolfgang Maret   JOURNAL OF INORGANIC BIOCHEMISTRY

SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation

(2011) A. S. Kristensen et al.   PHARMACOLOGICAL REVIEWS

The ins and outs of biological zinc sites

(2009) David S. Auld   BIOMETALS

Zinc treatment for symptomatic Wilson disease: Moving forward by looking back

(2009) Michael Schilsky   HEPATOLOGY

Long-term exclusive zinc monotherapy in symptomatic Wilson disease: Experience in 17 patients

(2009) Francisca H. H. Linn et al.   HEPATOLOGY

Metalloproteins and metal sensing

(2009) Kevin J. Waldron et al.   NATURE

Zinc in the physiology and pathology of the CNS

(2009) Stefano L. Sensi et al.   NATURE REVIEWS NEUROSCIENCE

Impairment of nigrostriatal dopamine neurotransmission by manganese is mediated by pre-synaptic mechanism(s): implications to manganese-induced parkinsonism

(2008) Tomás R. Guilarte et al.   JOURNAL OF NEUROCHEMISTRY

Zinc regulates the dopamine transporter in a membrane potential and chloride dependent manner

(2008) Christian Pifl et al.   NEUROPHARMACOLOGY

Dominant psychiatric manifestations in Wilson's disease: A diagnostic and therapeutic challenge!

(2007) K. Srinivas et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES