Functional Transformation of C-reactive Protein by Hydrogen Peroxide

Streptococcus oralis Induces Lysosomal Impairment of Macrophages via Bacterial Hydrogen Peroxide

(2016) Nobuo Okahashi et al.   INFECTION AND IMMUNITY

An Intrinsically Disordered Motif Mediates Diverse Actions of Monomeric C-reactive Protein

(2016) Hai-Yun Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Carbohydrate-linked Phosphorylcholine of the Parasitic Nematode Product ES-62 Modulates Complement Activation

(2016) Umul Kulthum Ahmed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multifaceted anti-amyloidogenic and pro-amyloidogenic effects of C-reactive protein and serum amyloid P component in vitro

(2016) Daisaku Ozawa et al.   Scientific Reports

C-Reactive Protein Protects Mice against Pneumococcal Infection via Both Phosphocholine-Dependent and Phosphocholine-Independent Mechanisms

(2015) Toh B. Gang et al.   INFECTION AND IMMUNITY

An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode

(2015) Andrea Doni et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions

(2015) Michael Thiele et al.   JOURNAL OF IMMUNOLOGY

Factor H–Related Protein 5 Interacts with Pentraxin 3 and the Extracellular Matrix and Modulates Complement Activation

(2015) Ádám I. Csincsi et al.   JOURNAL OF IMMUNOLOGY

Streptococcus pneumoniaesecretes hydrogen peroxide leading to DNA damage and apoptosis in lung cells

(2015) Prashant Rai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Staggered Decameric Assembly of Human C-Reactive Protein Stabilized by Zinc Ions Revealed by X-ray Crystallography

(2015) Christophe Guillon et al.   PROTEIN AND PEPTIDE LETTERS

Immunohistochemical staining reveals C-reactive protein existing predominantly as altered conformation forms in inflammatory lesions

(2014) Ping Shi et al.   ACTA BIOLOGICA HUNGARICA

Dissociation of Pentameric to Monomeric C-Reactive Protein Localizes and Aggravates Inflammation

(2014) Jan R. Thiele et al.   CIRCULATION

C-reactive protein specifically enhances platelet-activating factor-induced inflammatory activity in vivo

(2014) Akira Sato et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

C-reactive protein is essential for innate resistance to pneumococcal infection

(2014) J. Paul Simons et al.   IMMUNOLOGY

A conformational change of C-reactive protein in burn wounds unmasks its proinflammatory properties

(2014) David Braig et al.   INTERNATIONAL IMMUNOLOGY

C-Reactive Protein-Bound Enzymatically Modified Low-Density Lipoprotein Does Not Transform Macrophages into Foam Cells

(2014) S. K. Singh et al.   JOURNAL OF IMMUNOLOGY

Human L-Ficolin Recognizes Phosphocholine Moieties of Pneumococcal Teichoic Acid

(2014) Emilie Vassal-Stermann et al.   JOURNAL OF IMMUNOLOGY

ATP Modulates Acute Inflammation In Vivo through Dual Oxidase 1-Derived H2O2 Production and NF- B Activation

(2014) S. de Oliveira et al.   JOURNAL OF IMMUNOLOGY

Recognition Functions of Pentameric C-Reactive Protein in Cardiovascular Disease

(2014) Alok Agrawal et al.   MEDIATORS OF INFLAMMATION

Modified C-reactive protein interacts with platelet glycoprotein Ibα

(2014) Magdalena Boncler et al.   Pharmacological Reports

Obesity Associated Molecular Forms of C-Reactive Protein in Human

(2014) Bela F. Asztalos et al.   PLoS One

Oxidative Stress Sensitizes Retinal Pigmented Epithelial (RPE) Cells to Complement-mediated Injury in a Natural Antibody-, Lectin Pathway-, and Phospholipid Epitope-dependent Manner

(2013) Kusumam Joseph et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

C-reactive protein/oxidised low-density lipoprotein/β2-glycoprotein I complex promotes atherosclerosis in diabetic BALB/c mice via p38mitogen-activated protein kinase signal pathway

(2013) Rui Zhang et al.   Lipids in Health and Disease

Gain of function of immunoglobulins after partial unfolding or cofactor binding

(2013) Jordan D. Dimitrov et al.   MOLECULAR IMMUNOLOGY

Sustained Submicromolar H2O2Levels Induce Hepcidin via Signal Transducer and Activator of Transcription 3 (STAT3)

(2012) Gunda Millonig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The pro-atherogenic effects of macrophages are reduced upon formation of a complex between C-reactive protein and lysophosphatidylcholine

(2012) Mi-Kyung Chang et al.   Journal of Inflammation-London

Collagen-induced arthritis is exacerbated in C-reactive protein-deficient mice

(2011) Nicholas R. Jones et al.   ARTHRITIS AND RHEUMATISM

Pathophysiological condition changes the conformation of a flexible FBG-related protein, switching it from pathogen-recognition to host-interaction

(2011) Jing Zhang et al.   BIOCHIMIE

A redox switch in C-reactive protein modulates activation of endothelial cells

(2011) Ming-Yu Wang et al.   FASEB JOURNAL

Roles of Oxidative Stress and Redox Regulation in Atherosclerosis

(2011) Takahito Kondo et al.   Journal of Atherosclerosis and Thrombosis

Exposing a Hidden Functional Site of C-reactive Protein by Site-directed Mutagenesis

(2011) Sanjay K. Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Acidic pH-dependent Ligands of Pentameric C-reactive Protein

(2010) David J. Hammond et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dissociation of Pentameric to Monomeric C-Reactive Protein on Activated Platelets Localizes Inflammation to Atherosclerotic Plaques

(2009) Steffen U. Eisenhardt et al.   CIRCULATION RESEARCH

The binding of C-reactive protein, in the presence of phosphoethanolamine, to low-density lipoproteins is due to phosphoethanolamine-generated acidic pH

(2009) Sanjay K. Singh et al.   CLINICA CHIMICA ACTA

Monomeric C-Reactive Protein Decreases Acetylated LDL Uptake in Human Endothelial Cells

(2009) S. B. Schwedler et al.   CLINICAL CHEMISTRY

C-reactive Protein Exists in an NaCl Concentration-dependent Pentamer-Decamer Equilibrium in Physiological Buffer

(2009) Azubuike I. Okemefuna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The vicious circle between oxidative stress and inflammation in atherosclerosis

(2009) Maarten Hulsmans et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Complement Factor H Binds to Denatured Rather than to Native Pentameric C-reactive Protein

(2008) Svetlana Hakobyan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox Regulation in the Extracellular Environment

(2007) Filomena G. Ottaviano et al.   CIRCULATION JOURNAL