The bacterial arginine glycosyltransferase effector NleB preferentially modifies Fas-associated death domain protein (FADD)

NleB/SseK effectors fromCitrobacter rodentium,Escherichia coli, andSalmonella entericadisplay distinct differences in host substrate specificity

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Threonine eliminylation by bacterial phosphothreonine lyases rapidly causes cross-linking of mitogen-activated protein kinase (MAPK) in live cells

(2017) Benoit M. Meijer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interactome disassembly during apoptosis occurs independent of caspase cleavage

(2017) Nichollas E Scott et al.   Molecular Systems Biology

Synthesis of rhamnosylated arginine glycopeptides and determination of the glycosidic linkage in bacterial elongation factor P

(2017) Siyao Wang et al.   Chemical Science

EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation

(2017) Jaclyn S. Pearson et al.   Nature Microbiology

The Genetics of EnteropathogenicEscherichia coliVirulence

(2016) Jaclyn S. Pearson et al.   Annual Review of Genetics

Mutagenesis and Functional Analysis of the Bacterial Arginine Glycosyltransferase Effector NleB1 from Enteropathogenic Escherichia coli

(2016) Tania Wong Fok Lung et al.   INFECTION AND IMMUNITY

Citrobacter rodentiumNleB Protein Inhibits Tumor Necrosis Factor (TNF) Receptor-associated Factor 3 (TRAF3) Ubiquitination to Reduce Host Type I Interferon Production

(2016) Xiaofei Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sugar and Spice Make Bacteria Not Nice: Protein Glycosylation and Its Influence in Pathogenesis

(2016) Ezequiel Valguarnera et al.   JOURNAL OF MOLECULAR BIOLOGY

Quantitative Mass Spectrometry Identifies Novel Host Binding Partners for Pathogenic Escherichia coli Type III Secretion System Effectors

(2016) Robyn J. Law et al.   JOURNAL OF PROTEOME RESEARCH

Bacterial virulence factor inhibits caspase-4/11 activation in intestinal epithelial cells

(2016) M A Pallett et al.   Mucosal Immunology

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

Myristoylome Profiling Reveals a Concerted Mechanism of ARF GTPase Deacylation by the Bacterial Protease IpaJ

(2015) Nikolay Burnaevskiy et al.   MOLECULAR CELL

High-throughput phosphoproteomics reveals in vivo insulin signaling dynamics

(2015) Sean J Humphrey et al.   NATURE BIOTECHNOLOGY

Arginine-rhamnosylation as new strategy to activate translation elongation factor P

(2015) Jürgen Lassak et al.   Nature Chemical Biology

2016 update of the PRIDE database and its related tools

(2015) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

Discovery of a nucleocytoplasmic O-mannose glycoproteome in yeast

(2015) Adnan Halim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesis of and Specific Antibody Generation for Glycopeptides with ArginineN-GlcNAcylation

(2014) Man Pan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ

(2014) Jürgen Cox et al.   MOLECULAR & CELLULAR PROTEOMICS

Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome

(2014) Hao Xu et al.   NATURE

Time-resolved cellular effects induced by TcdA fromClostridium difficile

(2014) Nelli Jochim et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

NleB, a Bacterial Effector with Glycosyltransferase Activity, Targets GAPDH Function to Inhibit NF-κB Activation

(2013) Xiaofei Gao et al.   Cell Host & Microbe

Substrate Specificity of Clostridial Glucosylating Toxins and Their Function on Colonocytes Analyzed by Proteomics Techniques

(2013) Johannes Zeiser et al.   JOURNAL OF PROTEOME RESEARCH

Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study

(2013) Karen L Kotloff et al.   LANCET

A SILAC-based Approach Identifies Substrates of Caspase-dependent Cleavage upon TRAIL-induced Apoptosis

(2013) Gabriele Stoehr et al.   MOLECULAR & CELLULAR PROTEOMICS

Pathogen blocks host death receptor signalling by arginine GlcNAcylation of death domains

(2013) Shan Li et al.   NATURE

A type III effector antagonizes death receptor signalling during bacterial gut infection

(2013) Jaclyn S. Pearson et al.   NATURE

pLogo: a probabilistic approach to visualizing sequence motifs

(2013) Joseph P O'Shea et al.   NATURE METHODS

Large-scale identification of ubiquitination sites by mass spectrometry

(2013) Namrata D Udeshi et al.   Nature Protocols

Proteome-wide enrichment of proteins modified by lysine methylation

(2013) Scott M Carlson et al.   Nature Protocols

The E. coli Effector Protein NleF Is a Caspase Inhibitor

(2013) Sonja Blasche et al.   PLoS One

Dynamics of the Type III Secretion System Activity of Enteropathogenic Escherichia coli

(2013) E. Mills et al.   mBio

Refined Preparation and Use of Anti-diglycine Remnant (K-ε-GG) Antibody Enables Routine Quantification of 10,000s of Ubiquitination Sites in Single Proteomics Experiments

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Parallel Reaction Monitoring for High Resolution and High Mass Accuracy Quantitative, Targeted Proteomics

(2012) Amelia C. Peterson et al.   MOLECULAR & CELLULAR PROTEOMICS

Regulation of CD95/Fas signaling at the DISC

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Enteropathogenic Escherichia coli infection in children

(2011) Theresa J. Ochoa et al.   CURRENT OPINION IN INFECTIOUS DISEASES

A type III effector protease NleC from enteropathogenic Escherichia coli targets NF-κB for degradation

(2011) Jaclyn S. Pearson et al.   MOLECULAR MICROBIOLOGY

Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation

(2011) Li Zhang et al.   NATURE

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Simultaneous Glycan-Peptide Characterization Using Hydrophilic Interaction Chromatography and Parallel Fragmentation by CID, Higher Energy Collisional Dissociation, and Electron Transfer Dissociation MS Applied to theN-Linked Glycoproteome ofCampylobacter jejuni

(2010) Nichollas E. Scott et al.   MOLECULAR & CELLULAR PROTEOMICS

Generation of acetyllysine antibodies and affinity enrichment of acetylated peptides

(2010) Kun-Liang Guan et al.   Nature Protocols

Protein glycosylation in bacteria: sweeter than ever

(2010) Harald Nothaft et al.   NATURE REVIEWS MICROBIOLOGY

The Type III Effectors NleE and NleB from Enteropathogenic E. coli and OspZ from Shigella Block Nuclear Translocation of NF-κB p65

(2010) Hayley J. Newton et al.   PLoS Pathogens

NleC, a Type III Secretion Protease, Compromises NF-κB Activation by Targeting p65/RelA

(2010) Hilo Yen et al.   PLoS Pathogens

The effector repertoire of enteropathogenic E. coli: ganging up on the host cell

(2009) Paul Dean et al.   CURRENT OPINION IN MICROBIOLOGY

The Many Roles of FAS Receptor Signaling in the Immune System

(2009) Andreas Strasser et al.   IMMUNITY

Mascot-Derived False Positive Peptide Identifications Revealed by Manual Analysis of Tandem Mass Spectra

(2009) Yue Chen et al.   JOURNAL OF PROTEOME RESEARCH

Enrichment and Site Mapping ofO-LinkedN-Acetylglucosamine by a Combination of Chemical/Enzymatic Tagging, Photochemical Cleavage, and Electron Transfer Dissociation Mass Spectrometry

(2009) Zihao Wang et al.   MOLECULAR & CELLULAR PROTEOMICS

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY