Increased levels of Gab1 and Gab2 adaptor proteins skew interleukin-4 (IL-4) signaling toward M2 macrophage-driven pulmonary fibrosis in mice
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Title
Increased levels of Gab1 and Gab2 adaptor proteins skew interleukin-4 (IL-4) signaling toward M2 macrophage-driven pulmonary fibrosis in mice
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 292, Issue 34, Pages 14003-14015
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2017-07-08
DOI
10.1074/jbc.m117.802066
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- New insights into the multidimensional concept of macrophage ontogeny, activation and function
- (2016) Florent Ginhoux et al. NATURE IMMUNOLOGY
- Pulmonary Macrophages: A New Therapeutic Pathway in Fibrosing Lung Disease?
- (2016) Adam J. Byrne et al. TRENDS IN MOLECULAR MEDICINE
- Monocyte and Macrophage Plasticity in Tissue Repair and Regeneration
- (2015) Amitava Das et al. AMERICAN JOURNAL OF PATHOLOGY
- IRAK-M Promotes Alternative Macrophage Activation and Fibroproliferation in Bleomycin-Induced Lung Injury
- (2015) Megan N. Ballinger et al. JOURNAL OF IMMUNOLOGY
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- (2014) Peter J. Murray et al. IMMUNITY
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- (2014) Bo Tao et al. JOURNAL OF IMMUNOLOGY
- The In Vivo Fibrotic Role of FIZZ1 in Pulmonary Fibrosis
- (2014) Tianju Liu et al. PLoS One
- Flow Cytometric Analysis of Macrophages and Dendritic Cell Subsets in the Mouse Lung
- (2013) Alexander V. Misharin et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Interleukin-4- and Interleukin-13-Mediated Alternatively Activated Macrophages: Roles in Homeostasis and Disease
- (2013) Steven J. Van Dyken et al. Annual Review of Immunology
- MMP28 promotes macrophage polarization toward M2 cells and augments pulmonary fibrosis
- (2013) S. A. Gharib et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Monocytes Control Second-Phase Neutrophil Emigration in Established Lipopolysaccharide-induced Murine Lung Injury
- (2012) Kevin Dhaliwal et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Docking protein Gab2 regulates mucin expression and goblet cell hyperplasia through TYK2/STAT6 pathway
- (2012) Xue Zhang et al. FASEB JOURNAL
- Pulmonary fibrosis: patterns and perpetrators
- (2012) Paul W. Noble et al. JOURNAL OF CLINICAL INVESTIGATION
- Macrophage plasticity and polarization: in vivo veritas
- (2012) Antonio Sica et al. JOURNAL OF CLINICAL INVESTIGATION
- Ly6ChiMonocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis
- (2011) Michael A. Gibbons et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Integrating mechanisms of pulmonary fibrosis
- (2011) Thomas A. Wynn JOURNAL OF EXPERIMENTAL MEDICINE
- Idiopathic pulmonary fibrosis
- (2011) Talmadge E King et al. LANCET
- Alternatively activated alveolar macrophages in pulmonary fibrosis—mediator production and intracellular signal transduction
- (2010) Dmitri V. Pechkovsky et al. CLINICAL IMMUNOLOGY
- Alternative Activation of Macrophages: Mechanism and Functions
- (2010) Siamon Gordon et al. IMMUNITY
- The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
- (2010) Takashi Satoh et al. NATURE IMMUNOLOGY
- Serum and BALF YKL-40 levels are predictors of survival in idiopathic pulmonary fibrosis
- (2010) Nicoline M. Korthagen et al. RESPIRATORY MEDICINE
- Macrophages: Master Regulators of Inflammation and Fibrosis
- (2010) Thomas Wynn et al. SEMINARS IN LIVER DISEASE
- Function, regulation and pathological roles of the Gab/DOS docking proteins
- (2009) Franziska U Wöhrle et al. Cell Communication and Signaling
- Non-redundant roles of the Gab1 and Gab2 scaffolding adapters in VEGF-mediated signalling, migration, and survival of endothelial cells
- (2009) Christine Caron et al. CELLULAR SIGNALLING
- Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis
- (2009) John T. Pesce et al. PLoS Pathogens
- Alternative Activation of Macrophages: An Immunologic Functional Perspective
- (2008) Fernando O. Martinez et al. Annual Review of Immunology
- Murine gammaherpesvirus-induced fibrosis is associated with the development of alternatively activated macrophages
- (2008) Babunilayam Gangadharan et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Type I IL-4Rs Selectively Activate IRS-2 to Induce Target Gene Expression in Macrophages
- (2008) N. M. Heller et al. Science Signaling
- Untangling the Complex Web of IL-4- and IL-13-Mediated Signaling Pathways
- (2008) M. Wills-Karp et al. Science Signaling
- Murine models of pulmonary fibrosis
- (2007) Bethany B. Moore et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
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