Nuclear factor erythroid 2-related factor 2 enhances carcinogenesis by suppressing apoptosis and promoting autophagy in nickel-transformed cells

A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p-STAT3-MIR155-3p-CREBRF pathway

(2016) Hao Xue et al.   Autophagy

Cardioprotection from emulsified isoflurane postconditioning is lost in rats with streptozotocin-induced diabetes due to the impairment of Brg1/Nrf2/STAT3 signalling

(2016) Y. Wang et al.   CLINICAL SCIENCE

Luteolin inhibits viral-induced inflammatory response in RAW264.7 cells via suppression of STAT1/3 dependent NF-κB and activation of HO-1

(2016) Cheng-Wei Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inhibiting ROS-STAT3-dependent autophagy enhanced capsaicin–induced apoptosis in human hepatocellular carcinoma cells

(2016) Xun Chen et al.   FREE RADICAL RESEARCH

STAT3-dependent TXNDC17 expression mediates Taxol resistance through inducing autophagy in human colorectal cancer cells

(2016) Zhongde Zhang et al.   GENE

Garcinone D, a natural xanthone promotes C17.2 neural stem cell proliferation: Possible involvement of STAT3/Cyclin D1 pathway and Nrf2/HO-1 pathway

(2016) Xiaohong Yang et al.   NEUROSCIENCE LETTERS

Antioncogenic and Oncogenic Properties of Nrf2 in Arsenic-induced Carcinogenesis

(2015) Young-Ok Son et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nrf2/p62 Signaling in Apoptosis Resistance and Its Role in Cadmium-induced Carcinogenesis

(2014) Young-Ok Son et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Marburg Virus VP24 Protein Interacts with Keap1 to Activate the Cytoprotective Antioxidant Response Pathway

(2014) Megan R. Edwards et al.   Cell Reports

The role of Stat3 in glioblastoma multiforme

(2013) Rodney B. Luwor et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Autophagy in Toxicology: Cause or Consequence?

(2012) Sten Orrenius et al.   Annual Review of Pharmacology and Toxicology

Nrf2-induced antiapoptotic Bcl-xL protein enhances cell survival and drug resistance

(2012) Suryakant K. Niture et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nrf2 Protein Up-regulates Antiapoptotic Protein Bcl-2 and Prevents Cellular Apoptosis

(2012) Suryakant K. Niture et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cadmium induces carcinogenesis in BEAS-2B cells through ROS-dependent activation of PI3K/AKT/GSK-3β/β-catenin signaling

(2012) Young-Ok Son et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Potential role of p62 in tumor development

(2011) Masaaki Komatsu   Autophagy

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Cadmium induces autophagy through ROS-dependent activation of the LKB1–AMPK signaling in skin epidermal cells

(2011) Young-Ok Son et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

High Levels of Nrf2 Determine Chemoresistance in Type II Endometrial Cancer

(2010) T. Jiang et al.   CANCER RESEARCH

Reactive Oxygen Species-Activated Akt/ASK1/p38 Signaling Pathway in Nickel Compound-Induced Apoptosis in BEAS 2B Cells

(2010) Jingju Pan et al.   CHEMICAL RESEARCH IN TOXICOLOGY

IL-6 Trans-Signaling Modulates TLR4-Dependent Inflammatory Responses via STAT3

(2010) C. J. Greenhill et al.   JOURNAL OF IMMUNOLOGY

Loss of Kelch-Like ECH-Associated Protein 1 Function in Prostate Cancer Cells Causes Chemoresistance and Radioresistance and Promotes Tumor Growth

(2010) P. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

The Dual Roles of c-Jun NH2-Terminal Kinase Signaling in Cr(VI)-Induced Apoptosis in JB6 Cells

(2010) Y.-O. Son et al.   TOXICOLOGICAL SCIENCES

Heterochromatinization as a Potential Mechanism of Nickel-Induced Carcinogenesis

(2009) Thomas P. Ellen et al.   BIOCHEMISTRY

The Double-Edged Sword of Autophagy Modulation in Cancer

(2009) E. White et al.   CLINICAL CANCER RESEARCH

Association of reactive oxygen species levels and radioresistance in cancer stem cells

(2009) Maximilian Diehn et al.   NATURE

Cadmium Induces Intracellular Ca2+- and H2O2-Dependent Apoptosis through JNK- and p53-Mediated Pathways in Skin Epidermal Cell line

(2009) Young-Ok Son et al.   TOXICOLOGICAL SCIENCES

Loss of Keap1 Function Activates Nrf2 and Provides Advantages for Lung Cancer Cell Growth

(2008) T. Ohta et al.   CANCER RESEARCH

Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2

(2008) X.-J. Wang et al.   CARCINOGENESIS

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

Activation of Nrf2 in Defense against Cadmium-Induced Oxidative Stress†

(2008) Xiaoqing He et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The function of Stat3 in tumor cells and their microenvironment

(2008) Bernd Groner et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Genetic and Epigenetic Mechanisms in Metal Carcinogenesis and Cocarcinogenesis: Nickel, Arsenic, and Chromium

(2007) Konstantin Salnikow et al.   CHEMICAL RESEARCH IN TOXICOLOGY