A novel mechanism for Ca2+/calmodulin-dependent protein kinase II targeting to L-type Ca2+channels that initiates long-range signaling to the nucleus

A Novel Human CAMK2A Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors

(2017) Jason R. Stephenson et al.   JOURNAL OF NEUROSCIENCE

Excitation-Transcription Coupling in Parvalbumin-Positive Interneurons Employs a Novel CaM Kinase-Dependent Pathway Distinct from Excitatory Neurons

(2016) Samuel M. Cohen et al.   NEURON

Sequential ionic and conformational signaling by calcium channels drives neuronal gene expression

(2016) B. Li et al.   SCIENCE

Quantitative Proteomics Analysis of CaMKII Phosphorylation and the CaMKII Interactome in the Mouse Forebrain

(2015) Anthony J. Baucum et al.   ACS Chemical Neuroscience

Evolutionary and functional perspectives on signaling from neuronal surface to nucleus

(2015) Samuel M. Cohen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

γCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression

(2014) Huan Ma et al.   CELL

Synaptic, transcriptional and chromatin genes disrupted in autism

(2014) Silvia De Rubeis et al.   NATURE

The Cav1.2 N terminus contains a CaM kinase site that modulates channel trafficking and function

(2014) Brett A. Simms et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Phosphorylation and Feedback Regulation of Metabotropic Glutamate Receptor 1 by Calcium/Calmodulin-Dependent Protein Kinase II

(2013) D.-Z. Jin et al.   JOURNAL OF NEUROSCIENCE

Nuclear calcium signalling in the regulation of brain function

(2013) Hilmar Bading   NATURE REVIEWS NEUROSCIENCE

Exploring the dominant role of Cav1 channels in signalling to the nucleus

(2012) Huan Ma et al.   BIOSCIENCE REPORTS

CaV1 and CaV2 Channels Engage Distinct Modes of Ca2+ Signaling to Control CREB-Dependent Gene Expression

(2012) Damian G. Wheeler et al.   CELL

A Mechanism for Tunable Autoinhibition in the Structure of a Human Ca2+/Calmodulin- Dependent Kinase II Holoenzyme

(2011) Luke H. Chao et al.   CELL

Characterization of a Central Ca2+/Calmodulin-dependent Protein Kinase IIα/β Binding Domain in Densin That Selectively Modulates Glutamate Receptor Subunit Phosphorylation

(2011) Yuxia Jiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuronal Activity-Regulated Gene Transcription in Synapse Development and Cognitive Function

(2011) A. E. West et al.   Cold Spring Harbor Perspectives in Biology

Calcium Signaling in Synapse-to-Nucleus Communication

(2011) A. M. Hagenston et al.   Cold Spring Harbor Perspectives in Biology

Ca2+-Dependent Facilitation of Cav1.3 Ca2+ Channels by Densin and Ca2+/Calmodulin-Dependent Protein Kinase II

(2010) M. A. Jenkins et al.   JOURNAL OF NEUROSCIENCE

CaV1.2  -subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations

(2010) O. M. Koval et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the CaMKIIδ/Calmodulin Complex Reveals the Molecular Mechanism of CaMKII Kinase Activation

(2010) Peter Rellos et al.   PLOS BIOLOGY

An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol

(2009) Huanting Liu et al.   BMC BIOTECHNOLOGY

Reciprocal Interactions Regulate Targeting of Calcium Channel β Subunits and Membrane Expression of α1Subunits in Cultured Hippocampal Neurons

(2009) Gerald J. Obermair et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CaMKII associates with CaV1.2 L-type calcium channels via selected β subunits to enhance regulatory phosphorylation

(2009) Sunday A. Abiria et al.   JOURNAL OF NEUROCHEMISTRY

Transcription Factors in Long-Term Memory and Synaptic Plasticity

(2009) Cristina M. Alberini   PHYSIOLOGICAL REVIEWS

Signaling Mechanisms Linking Neuronal Activity to Gene Expression and Plasticity of the Nervous System

(2008) Steven W. Flavell et al.   Annual Review of Neuroscience

Differential Regulated Interactions of Calcium/Calmodulin-Dependent Protein Kinase II with Isoforms of Voltage-Gated Calcium Channel β Subunits†

(2008) Chad E. Grueter et al.   BIOCHEMISTRY

Mechanism of Local and Global Ca2+ Sensing by Calmodulin in Complex with a Ca2+ Channel

(2008) Michael R. Tadross et al.   CELL

Modulation of Voltage- and Ca2+-dependent Gating of CaV1.3 L-type Calcium Channels by Alternative Splicing of a C-terminal Regulatory Domain

(2008) Anamika Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CaMKII locally encodes L-type channel activity to signal to nuclear CREB in excitation–transcription coupling

(2008) Damian G. Wheeler et al.   JOURNAL OF CELL BIOLOGY

A modular switch for spatial Ca2+ selectivity in the calmodulin regulation of CaV channels

(2008) Ivy E. Dick et al.   NATURE