Lactate-mediated mitoribosomal defects impair mitochondrial oxidative phosphorylation and promote hepatoma cell invasiveness

Structure and Function of the Mitochondrial Ribosome

(2016) Basil J. Greber et al.   Annual Review of Biochemistry

Maintenance and Expression of Mammalian Mitochondrial DNA

(2016) Claes M. Gustafsson et al.   Annual Review of Biochemistry

MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism

(2016) Changhan Lee et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mammalian mitochondrial ribosomal small subunit (MRPS) genes: A putative role in human disease

(2016) Gopal Gopisetty et al.   GENE

Identification of a mitochondrial defect gene signature revealsNUPR1as a key regulator of liver cancer progression

(2015) Young-Kyoung Lee et al.   HEPATOLOGY

A Metabolic Phenotype Based on Mitochondrial Ribosomal Protein Expression as a Predictor of Lymph Node Metastasis in Papillary Thyroid Carcinoma

(2015) Jandee Lee et al.   MEDICINE

The complete structure of the 55S mammalian mitochondrial ribosome

(2015) B. J. Greber et al.   SCIENCE

The complete structure of the large subunit of the mammalian mitochondrial ribosome

(2014) Basil J. Greber et al.   NATURE

An integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer

(2014) Michael L Gatza et al.   NATURE GENETICS

RETRACTED ARTICLE: Human mitochondrial genome flaws and risk of cancer

(2013) Alok Kumar Singh et al.   Mitochondrial DNA

Decreased mitochondrial OGG1 expression is linked to mitochondrial defects and delayed hepatoma cell growth

(2013) Young-Kyoung Lee et al.   MOLECULES AND CELLS

Suppression of Mitochondrial Complex I Influences Cell Metastatic Properties

(2013) Xuelian He et al.   PLoS One

Mitochondrial Dysfunction Promotes Breast Cancer Cell Migration and Invasion through HIF1α Accumulation via Increased Production of Reactive Oxygen Species

(2013) Jia Ma et al.   PLoS One

Mitochondrial dysfunction promotes cell migration via reactive oxygen species-enhanced β5-integrin expression in human gastric cancer SC-M1 cells

(2012) Wen-Yi Hung et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mitochondria “fuel” breast cancer metabolism: Fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells

(2012) Federica Sotgia et al.   CELL CYCLE

GSK3 inactivation is involved in mitochondrial complex IV defect in transforming growth factor (TGF) β1-induced senescence

(2012) Hae-Ok Byun et al.   EXPERIMENTAL CELL RESEARCH

Involvement of mitophagy in oncogenic K-Ras-induced transformation

(2011) June-Hyung Kim et al.   Autophagy

Genetic polymorphisms and breast cancer risk: evidence from meta-analyses, pooled analyses, and genome-wide association studies

(2011) Sihua Peng et al.   BREAST CANCER RESEARCH AND TREATMENT

Functional Interaction between Responses to Lactic Acidosis and Hypoxia Regulates Genomic Transcriptional Outputs

(2011) X. Tang et al.   CANCER RESEARCH

Decreased lactate dehydrogenase B expression enhances claudin 1-mediated hepatoma cell invasiveness via mitochondrial defects

(2011) June-Hyung Kim et al.   EXPERIMENTAL CELL RESEARCH

Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fibroblasts and glycolytic tumor cells in the tumor microenvironment

(2011) Yanique I. Rattigan et al.   EXPERIMENTAL CELL RESEARCH

Genetic insights into OXPHOS defect and its role in cancer

(2010) Dhyan Chandra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes

(2010) J. H. Taube et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Complex I decrease is responsible for bioenergetic dysfunction in K-ras transformed cells

(2009) Alessandra Baracca et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS