The Ubiquitin-like with PHD and Ring Finger Domains 1 (UHRF1)/DNA Methyltransferase 1 (DNMT1) Axis Is a Primary Regulator of Cell Senescence

Ubiquitin E3 ligase UHRF1 regulates p53 ubiquitination and p53-dependent cell apoptosis in clear cell Renal Cell Carcinoma

(2015) Jian Ma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

UHRF1 Overexpression Drives DNA Hypomethylation and Hepatocellular Carcinoma

(2014) Raksha Mudbhary et al.   CANCER CELL

Regulation of p53 and Rb Links the Alternative NF-κB Pathway to EZH2 Expression and Cell Senescence

(2014) Alessio Iannetti et al.   PLoS Genetics

SUV39H1 downregulation induces deheterochromatinization of satellite regions and senescence after exposure to ionizing radiation

(2014) Corinne Sidler et al.   Frontiers in Genetics

Implications of time-series gene expression profiles of replicative senescence

(2013) You-Mi Kim et al.   AGING CELL

Involvement of mitophagy in oncogenic K-Ras-induced transformation

(2011) June-Hyung Kim et al.   Autophagy

ADP-ribose polymers localized on Ctcf–Parp1–Dnmt1 complex prevent methylation of Ctcf target sites

(2011) Michele Zampieri et al.   BIOCHEMICAL JOURNAL

Wnt5a Suppresses Epithelial Ovarian Cancer by Promoting Cellular Senescence

(2011) B. G. Bitler et al.   CANCER RESEARCH

Four faces of cellular senescence

(2011) Francis Rodier et al.   JOURNAL OF CELL BIOLOGY

DNA Methyltransferase Controls Stem Cell Aging by Regulating BMI1 and EZH2 through MicroRNAs

(2011) Ah-Young So et al.   PLoS One

Cellular senescence: A link between cancer and age-related degenerative disease?

(2011) Judith Campisi et al.   SEMINARS IN CANCER BIOLOGY

Regulation of DNA methyltransferase 1 by interactions and modifications

(2011) Weihua Qin et al.   Nucleus

The DNA-binding activity of mouse DNA methyltransferase 1 is regulated by phosphorylation with casein kinase 1δ/ε

(2010) Yasunori Sugiyama et al.   BIOCHEMICAL JOURNAL

Dysregulation of p53/Sp1 Control Leads to DNA Methyltransferase-1 Overexpression in Lung Cancer

(2010) R.-K. Lin et al.   CANCER RESEARCH

Widespread and tissue specific age-related DNA methylation changes in mice

(2010) S. Maegawa et al.   GENOME RESEARCH

Epigenetic alterations in aging

(2010) Susana Gonzalo   JOURNAL OF APPLIED PHYSIOLOGY

Cutting edge: Chk1 directs senescence and mitotic catastrophe in recovery from G2 checkpoint arrest

(2010) Angela Poehlmann et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Establishing, maintaining and modifying DNA methylation patterns in plants and animals

(2010) Julie A. Law et al.   NATURE REVIEWS GENETICS

A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability

(2010) Pierre-Olivier Estève et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNMT1 Stability Is Regulated by Proteins Coordinating Deubiquitination and Acetylation-Driven Ubiquitination

(2010) Z. Du et al.   Science Signaling

A comparative analysis of the cell biology of senescence and aging

(2009) Eun Seong Hwang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Senescence delay and repression of p16 INK4a by Lsh via recruitment of histone deacetylases in human diploid fibroblasts

(2009) Rui Zhou et al.   NUCLEIC ACIDS RESEARCH

Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells

(2009) P.-O. Esteve et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced glycogenesis is involved in cellular senescence via GSK3/GS modulation

(2008) Yong-Hak Seo et al.   AGING CELL

Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism

(2008) Kyohei Arita et al.   NATURE