Article
Biochemistry & Molecular Biology
Jai Krishna Mahto, Neetu Neetu, Bhairavnath Waghmode, Eugene Kuatsjah, Monica Sharma, Debabrata Sircar, Ashwani Kumar Sharma, Shailly Tomar, Lindsay D. Eltis, Pravindra Kumar
Summary: Phthalate, a plasticizer, endocrine disruptor, and potential carcinogen, can be degraded by various bacteria through the action of enzyme PDOKF1. This enzyme has high catalytic activity towards phthalate and a unique hexameric structure. Residues Arg207 and Arg244 play crucial roles in positioning substrates for regiospecific hydroxylation at the active site of PDOKF1.
JOURNAL OF BIOLOGICAL CHEMISTRY
(2021)
Article
Biotechnology & Applied Microbiology
Huawei Li, Shaoxuan Ding, Wanchao Song, Yonghui Zhang, Jincheng Ding, Jie Lu
Summary: The study focused on anaerobic iron-reducing bacteria, specifically Comamonas testosteroni Y1, and found that it could utilize glucose and sucrose as electron donors during the iron reduction process. Additionally, the relationship between cell growth and Fe(III) formation was investigated, with a model successfully describing the correlation between the two variables.
BIOCHEMICAL ENGINEERING JOURNAL
(2022)
Article
Environmental Sciences
Lijin An, Xiong Luo, Minghan Wu, Liling Feng, Kaixiang Shi, Gejiao Wang, Barry P. Rosen, Mingshun Li
Summary: The study reveals a novel bacterial P-type ATPase playing a crucial role in antimony detoxification, with unique structure and function compared to other members. AntC acts as an Sb(III) chaperone facilitating Sb(III) efflux, enhancing resistance to Sb(III).
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Diana C. Pacyga, Joseph C. Gardiner, Jodi A. Flaws, Zhong Li, Antonia M. Calafat, Susan A. Korrick, Susan L. Schantz, Rita S. Strakovsky
Summary: This study found that exposure to phthalates may impact gestational hormones in pregnant women, with potential for associations that vary by gestational age and fetal sex. Specifically, certain phthalate metabolites were positively associated with total estrogen and testosterone levels, while negatively associated with the estrogen/androgen ratio.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Biotechnology & Applied Microbiology
Masae Horinouchi, Toshiaki Hayashi
Summary: The study focused on the degradation pathway of steroids in Comamonas testosteroni TA441, revealing the enzymes and intermediate compounds involved in the process, as well as the specific ring-cleavage steps.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2021)
Article
Environmental Sciences
Xinrui Hao, Xiaoju Guan, Xingxing Zhao, Minpeng Ji, Xin Wen, Panpan Chen, Fenfen Chen, Jianying Yang, Qingquan Lian, Leping Ye, Haolin Chen
Summary: Studies have shown that phthalates, such as MEHP, can significantly inhibit the proliferation and differentiation of stem Leydig cells (SLCs). It also affects the differentiation of SLCs into Leydig cells and adipocytes.
Article
Microbiology
Didem AKSU, Mamadou Malick DIALLO, Umut SAHAR, Tayyibe A. L. P. A. Y. UYANIKER, Guven OZDEMIR
Summary: In this study, the ability of Comamonas testosteroni strain 3a2 to effectively degrade para-toluic acid was investigated. The strain was able to degrade up to 1000 mg/L of para-toluic acid within 14 hours, with the highest degradation yield observed in the presence of yeast extract as a nitrogen source. Additionally, genes for various dioxygenases were detected in the genomic DNA of 3a2, indicating their role in the degradation process.
ARCHIVES OF MICROBIOLOGY
(2021)
Article
Engineering, Environmental
Yuting Liang, Jiayi Li, Yaoyu He, Zhi Jiang, Wenfeng Shangguan
Summary: The study found that as the temperature increases, the model SVOC DMP gradually oxidizes on the surface of supported catalysts, with carbon dioxide as the main product, but aromatic products and small molecule products are still observed at different temperatures.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Engineering, Environmental
Yi Zhao, Xue-Nan Li, Hao Zhang, Jia-Gen Cui, Jia-Xin Wang, Ming-Shan Chen, Jin-Long Li
Summary: Male infertility is a significant concern due to the decline in sperm quality worldwide. Phthalates, particularly DEHP or its metabolite MEHP, have negative effects on male reproductive development and function, leading to reduced fertility. Lycopene, a natural antioxidant, has the potential to be used as a therapeutic option for male infertility. This research demonstrates that DEHP reduces testosterone production in Leydig cells and impairs secretory function in Sertoli cells, resulting in impaired spermatogenesis. Additionally, MEHP causes mitochondrial and oxidative damage, posing a serious threat to spermatogenesis. However, LYC supplementation reverses these changes. Mechanistically, DEHP disrupts the T/AR signaling pathway, contributing to male infertility. Overall, this study highlights the critical role of the T/AR signal transduction in male fertility and provides promising insights into the protective role of LYC in phthalate-induced male reproductive disorders.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Chemistry, Analytical
Wenhui Li, Xuecheng Zhang, Haojie Zhang, Cheng Zhang, Yingjie Chen, Cong Li, Yonghong Hu, Xiaoping Yu, Biao Zhang, Xiaodong Lin
Summary: A novel colorimetric immunoassay was developed using Pt@Au nanozymes and catalytic signal probes for the simultaneous detection of DMP and DBP. The method showed high sensitivity and accuracy and can be applied for quantitative analysis of DMP and DBP in baijiu and plastic bottled drinks.
Article
Environmental Sciences
Kun Gao, Bin Li, Chunye Xue, Jingwei Dong, Pingkang Qian, Qian Lu, Xiangyuan Deng
Summary: The study demonstrated that dimethyl phthalate (DMP) and diethyl phthalate (DEP) significantly inhibited photosynthesis and chlorophyll a biosynthesis of the marine diatom, leading to excessive ROS production. Moreover, the activities of antioxidant enzymes in the diatom increased with the increase of DMP and DEP concentrations, providing insights into the toxic mechanisms of phthalate esters in the marine environment and their ecological risks.
MARINE POLLUTION BULLETIN
(2021)
Article
Biotechnology & Applied Microbiology
R. Kaur, A. Kumari, G. Sharma, D. Singh, R. Kaur
Summary: The study aimed to explore the degradation potential of BBP and DMP by Bacillus marisflavi RR014 isolated from tap water, and to optimize the degradation process using response surface methodology. The results showed that the bacterium can degrade both phthalates under varying environmental conditions, and the degradation rate increases with pH, temperature, and salt concentration.
JOURNAL OF APPLIED MICROBIOLOGY
(2021)
Article
Environmental Sciences
Guowan Li, Zhujian Huang, Huashou Li, Zhenyao Zhang, Lihua Cui
Summary: The frequent detection and joint toxicity of sulfonamides (SAs) and phthalate acid esters (PAEs) in the water environment pose serious health and safety problems. Vertical flow constructed wetland (VFCW) provides a solution for reducing these problems. This study investigated the synergistic removal of sulfamethoxazole (SMX) and dimethyl phthalate (DMP) using various substrates in VFCW. Results showed that biochar, zeolite, vermiculite, peat, and sand exhibited excellent synergistic adsorption of SMX and DMP, providing an effective method to remove these substances.
Article
Microbiology
Zhigang He, Baopeng Ding, Qurban Ali, Huiyu Liu, Ying Zhao, Xiujuan Wang, Yingzuo Han, Huan Dong, Praveen Kumar Divvela, Yinghua Juan
Summary: Degradation of crop straw has been a challenge in the natural environment. Recently, there has been an increase in the exploration of cold-adapted microorganisms as they can solve the problem of corn straw degradation under low temperatures, offering new alternatives for sustainable agriculture.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Engineering, Environmental
Xiang Tang, Man Zhou, Guangming Zeng, Changzheng Fan
Summary: Different concentrations of DMP were found to have varying impacts on sludge anaerobic digestion, with 10.0 mg/L of DMP promoting methane production, favoring the growth of methanogens, and increasing the concentrations of certain dominant MGEs without changing the profile of ARGs dominated by multidrug resistance gene. This suggests that DMP may enhance the spread potential of ARGs.
CHEMICAL ENGINEERING JOURNAL
(2022)
