Journal
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
Volume 20, Issue 5, Pages 423-430Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2017.1335309
Keywords
Ranunculaceae; Delphinium; anthriscifolium; C-18-diterpenoid alkaloids; cytotoxicity
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Five new C-18-diterpenoid alkaloids, anthriscifoltines C-G (1-5), along with four known diterpenoid alkaloids anthriscifolcines C-F (6-9), were isolated from the extract of Delphinium anthriscifolium var. majus. Their structures were elucidated by extensive spectroscopic analyses (including 1D-, 2D-NMR, and HR-ESI-MS). Compounds 1-5 were also evaluated for their cytotoxic activity against MCF-7, HepG2, and H460 human cancer cell lines. [GRAPHICS] .
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