Article
Biotechnology & Applied Microbiology
Yunpeng Bai, Binhui Lin, Miao Wang, Haoliang Ding, Weibing Sun, Jian Sun
Summary: This study demonstrated that MOWHTO combined with arthroscopic microfracture can effectively improve clinical outcomes in the treatment of varus medial compartmental knee osteoarthritis. Cartilage regeneration can be promoted by correcting varus deformities, which affects clinical outcomes.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Orthopedics
Kotaro Miyazaki, Akira Maeyama, Ichiro Yoshimura, Tomohiro Kobayashi, Tetsuro Ishimatsu, Takuaki Yamamoto
Summary: This study aimed to evaluate the influence of hindfoot alignment on lower limb alignment after MOWHTO. The results showed that the preoperative hindfoot alignment angle was a significant predictive factor of postoperative limb alignment, and if the angle was greater than or equal to 15.9 degrees, surgeons should reconsider the operative procedure and correction angle.
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2023)
Article
Medicine, General & Internal
Yoon Hae Kwak, Dae-Kyung Kwak, Hyun-Soo Moon, Nan Young Kim, Jae-Sung Yee, Je-Hyun Yoo
Summary: This study identified significantly upregulated serum miRNAs after HTO as potential prognostic biomarkers, however, further studies are needed to elucidate their clinical implications.
Article
Orthopedics
Koji Iwasaki, Eiji Kondo, Shinji Matsubara, Masatake Matsuoka, Kaori Endo, Isao Yokota, Tomohiro Onodera, Norimasa Iwasaki
Summary: This study evaluated the distribution of subchondral bone density across the proximal tibia in nonarthritic knees and knees of patients with osteoarthritis before and after high tibial osteotomy (HTO). Results showed that HTO shifted the high-density areas of the medial compartment of the proximal tibial articular surface toward the lateral compartment, with an increase in the most lateral region of the medial compartment.
AMERICAN JOURNAL OF SPORTS MEDICINE
(2021)
Article
Multidisciplinary Sciences
Jung-Kwon Bae, Kang-Il Kim, Jun-Ho Kim, Hyun-Gon Gwak, Chanwoo Kim
Summary: The study evaluated changes in bone tracer uptake (BTU) after MOWHTO and its correlation with clinical symptoms, radiologic parameters, and cartilage regeneration. Results showed significant decrease in BTU of the medial femoral condyle and tibial plateau after 2 years, along with improvements in AKS scores and arthroscopic cartilage status. Lower BMI and postoperative valgus alignment were significant predictors for postoperative BTU decrease, but changes in BTU did not reflect cartilage regeneration or clinical outcomes in the mid-term follow-up.
Article
Orthopedics
Michael Schlumberger, Damian Oremek, Moritz Brielmaier, Uli Buntenbroich, Philipp Schuster, Bernd Fink
Summary: The study evaluated the outcomes of medial unicondylar knee arthroplasty (UKA) after failed high tibial osteotomy (HTO) for medial knee osteoarthritis, finding a 93.0% survival rate among patients followed for an average of 4.3 years. Complications included excessive valgus alignment and tibial loosening with femoropatellar degeneration. Overall, good-to-excellent results were achieved in most cases, with improvement in knee function and quality of life observed in the majority of patients.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2021)
Article
Orthopedics
Man Soo Kim, Jae Jung Kim, Ki Ho Kang, Kyung Jun Sin, Yong In
Summary: This study aimed to investigate the impact of generalized joint laxity on the postoperative alignment and clinical outcomes of medial opening-wedge high tibial osteotomy (MOWHTO). The results revealed that generalized joint laxity significantly affected the overcorrection of alignment following MOWHTO. However, there was no significant difference in patient-reported outcomes between patients with and without generalized joint laxity after MOWHTO within 2 years.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Orthopedics
Man Soo Kim, Jae Jung Kim, Ki Ho Kang, Joon Soo Ihm, Yong In
Summary: This study aimed to investigate the effects of Medial opening-wedge high tibial osteotomy (MOWHTO) on ankle symptoms and ankle and hindfoot alignments in patients with different severity of ankle osteoarthritis (OA). The study found that ankle pain worsened in patients with severe ankle OA, while patient-reported outcome measures for the knee joint showed no differences between the two groups of patients.
AMERICAN JOURNAL OF SPORTS MEDICINE
(2023)
Article
Orthopedics
Jung-Kwon Bae, Jun-Ho Kim, Kang-Il Kim, Sang Hak Lee, Dong-Won Seo
Summary: After medial open-wedge high tibial osteotomy (MOWHTO), medial meniscus extrusion (MME) improved over time and was significantly correlated with preoperative medial proximal tibial angle (MPTA). However, the changes in MME after MOWHTO did not reflect postoperative clinical outcomes and arthroscopic articular cartilage improvement.
ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY
(2022)
Article
Orthopedics
Axiang He, Yin Wang, Yanan Chen, Ying Zhou, Hui Zhang, Yanjie Mao, Wanjun Liu, Xianlong Zhang
Summary: Patients aged 55 years or older, with a BMI of 28 or higher, and postoperative LLD of 10 mm or more are more likely to develop symptomatic LLD. Older or heavier patients with an expected LLD greater than 10 mm after OWHTO should be informed about the possibility of postoperative LLD symptoms.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2021)
Article
Orthopedics
Sung-Sahn Lee, Young Keun Lee, Il Su Kim, Dong Jin Ryu, Eui Yub Jung, Do Kyung Lee, Joon Ho Wang
Summary: This study investigated time-dependent alignment changes and predictive factors for postoperative alignment change after opening-wedge high tibial osteotomy (OWHTO). The results showed that 42% of cases had a correction loss of more than 1 degree after OWHTO. The overall postoperative hip-knee-ankle (HKA) angles progressed towards varus. Preoperatively greater valgus stress joint line convergence angles and less medial joint space width were predictive factors for greater change in alignment towards varus.
ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE
(2022)
Article
Biophysics
Elaheh Elyasi, Antoine Perrier, Mathieu Bailet, Yohan Payan
Summary: A biomechanical model was developed to predict the impact of high tibial osteotomy on patellar position and found a correlation between the wedge opening angles and the patellar position after the surgery.
JOURNAL OF BIOMECHANICS
(2022)
Article
Orthopedics
Min Song, Xiaodong Lin, Weichang Han, Jingyi Li, Wengang Liu
Summary: This study aimed to compare the efficacy of proximal tibial tubercle osteotomy (PTO) and distal tibial tubercle osteotomy (DTO) for the treatment of medial compartment knee osteoarthritis. The study found that PTO carries a higher risk of postoperative complications compared to DTO, but both surgical techniques have similar effects in correcting knee varus deformity and improving knee function.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
Article
Orthopedics
B. L. Schelker, C. S. Moret, O. Dogan, F. Amsler, H. Rasch, R. W. Huegli, M. T. Hirschmann
Summary: This study suggests that preoperative SPECT/CT scans can help surgeons identify potential risk factors for inferior clinical outcomes in patients undergoing medial opening-wedge high tibial osteotomy (MOWHTO), with elevated BTU in the patellar region being a potential risk factor for postoperative pain and stiffness. Despite the limited number of participants, the study highlights the importance of preoperative SPECT in modern knee surgery to analyze loading patterns on different compartments of the knee.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2022)
Article
Orthopedics
Shuntaro Nejima, Ken Kumagai, Shunsuke Yamada, Masaichi Sotozawa, Dan Kumagai, Hironori Yamane, Yutaka Inaba
Summary: In this retrospective study of varus knee osteoarthritis patients, it was found that preoperative joint line convergence angle and medial proximal tibial angle were independent predictors for a postoperative MPTA > 95 degrees. Around 40% of cases still required double level osteotomy to correct the postoperative MPTA despite initial surgical planning.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Orthopedics
Kyun-Ho Shin, Ki-Mo Jang, Seung-Beom Han
Summary: This study compared the outcomes of total knee arthroplasty for varus osteoarthritis with intentionally allowed residual varus alignment and mechanical alignment. The results showed that allowing residual varus alignment restored the parallel joint line, reduced coronal gap imbalances, and resulted in better patient-reported outcomes.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2022)
Article
Orthopedics
Kyun-Ho Shin, Ki-Mo Jang, Seung-Beom Han
Summary: This study compared the reliability of two gap assessment methods and identified factors affecting component gaps other than planned gaps. The results showed that component gap measurements were more accurate, reliable, and correlated with planned gap balance compared to bone surface gap measurements.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2022)
Article
Orthopedics
Kyung Wook Nha, Seung Joo Kim, Jong Hun Park, Ji Hoon Bae, Ki-Mo Jang, Sang-Gyun Kim
Summary: This study investigated the incidence of one-way valve lesions and their impact on clinical outcomes in patients undergoing arthroscopic cystectomy for Baker's cysts. The results showed that arthroscopic cystectomy demonstrated good clinical results in patients with and without one-way valve lesions.
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2023)
Review
Medicine, General & Internal
Jun-Gu Park, Seung-Beom Han, Hye Chang Rhim, Ok Hee Jeon, Ki-Mo Jang
Summary: Although there have been significant improvements in clinical outcomes after anterior cruciate ligament reconstruction, residual rotational instability of the knee joint is still a major concern. The anterolateral ligament (ALL) has garnered attention as a potential stabilizer for anterolateral rotational instability, but controversies surrounding its existence, prevalence, and insertion points remain.
WORLD JOURNAL OF CLINICAL CASES
(2022)
Article
Orthopedics
Kwangho Chung, Min Jung, Ki-Mo Jang, Sang-Hoon Park, Bum Joon Nam, Hyungjun Kim, Sung-Hwan Kim
Summary: This first in-human study compared the clinical efficacy and safety of a combination of particulated costal allocartilage and microfracture versus microfracture alone in treating knee cartilage defects. The results showed that microfracture augmented with particulated costal allocartilage resulted in superior cartilage repair quality and comparable functional outcomes to microfracture alone at the 48-week follow-up.
ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE
(2023)
Article
Medicine, General & Internal
Jin Hyuck Lee, Hye Chang Rhim, Ki-Mo Jang
Summary: This study aimed to investigate whether adding Kinesio Taping (KT) to exercise therapy has any beneficial effect in the treatment of patellofemoral pain syndrome (PFPS). The results showed that adding KT did not provide extra benefits in quadriceps muscle strength, acceleration time, and AKPS among PFPS patients.
MEDICINA-LITHUANIA
(2023)
Review
Medicine, General & Internal
Chul-Soo Lee, Ok-Hee Jeon, Seung-Beom Han, Ki-Mo Jang
Summary: The medial collateral ligament (MCL) is an important supporting ligament of the knee joint, and injuries to the MCL are common with excessive valgus loading. While conservative treatment is often effective, the healing process can take several weeks to months and the biomechanical properties of the healed MCL may differ, increasing the risk of re-injury. Preclinical studies have shown promising results for mesenchymal stem cell (MSC)-based approaches in MCL injuries, but clinical studies in this area are lacking. MSC-based approaches have the potential to enhance healing of the MCL in the future.
MEDICINA-LITHUANIA
(2023)
Article
Medicine, General & Internal
Dae Keun Suh, Il-Yup Cho, Sehyun Noh, Dong Joo Yoon, Ki-Mo Jang
Summary: This study investigated the anatomical and biomechanical characteristics of the anterolateral ligament (ALL) in Korean cadaveric knee joints. The ALL was identified as a distinct ligament structure with a 100% prevalence, playing a protective role in the internal rotational stability of the knee joint. Isolated transection of the ALL did not significantly affect ALL footprint distances or functional stability tests.
MEDICINA-LITHUANIA
(2023)
Article
Cell Biology
Tae-Hwan Gil, Haiyan Zheng, Hyo Gyeong Lee, Ji-Won Shin, Sun Wook Hwang, Ki-Mo Jang, Ok Hee Jeon
Summary: Aging is a risk factor for osteoarthritis (OA) development. The therapeutic effect of senolytic drugs on OA is limited in aged mice. However, a drug combination of ABT263 and D+Q can reduce OA-related pain and peripheral sensitization.
Article
Medicine, General & Internal
Hye Chang Rhim, Ashley E. Gureck, Ki-Mo Jang
Summary: This case report presents three cases of obturator externus injury in professional soccer players, who initially presented with hip or groin pain commonly suspected to be quadriceps or adductor injuries. The players experienced pain on the left or right side after long distance shooting or passing during training sessions or matches. Magnetic resonance imaging (MRI) revealed grade II injury for two players and grade I injury for one player. Rehabilitation protocols, including relative rest, cryotherapy, and electrotherapy, were implemented and all patients were able to return to play after 10 days. The correct identification of obturator externus injury led to a favorable prognosis and relatively quick return to sport compared to quadricep or adductor injury.
MEDICINA-LITHUANIA
(2022)
Article
Medicine, General & Internal
Tae-Jin Lee, Ki-Mo Jang, Tae-Jin Kim, Sang-Min Lee, Ji-Hoon Bae
Summary: This study compared adjustable-loop femoral cortical suspensory fixation and interference screw fixation in terms of tunnel widening and clinical outcomes after anterior cruciate ligament reconstruction (ACLR). The results showed that tunnel widening in the adjustable-loop group was significantly greater than that in the interference screw group at the tibia levels. However, there were no significant differences between the two groups in terms of femoral tunnel widening and clinical outcomes at 2 years.
MEDICINA-LITHUANIA
(2022)
Article
Medicine, General & Internal
Jin Hyuck Lee, Ki Hun Shin, Seung-Beom Han, Kyo Sun Hwang, Seo Jun Lee, Ki-Mo Jang
Summary: Exercise therapy has been found to be effective for treating patellofemoral pain syndrome (PFPS). However, there is limited research on the effectiveness of balance exercise in PFPS patients. This study compared the outcomes of knee alignment-oriented static balance exercise (SBE) and dynamic balance exercise (DBE) in PFPS patients. The results showed that DBE was more effective in improving dynamic postural stability and quadriceps muscle reaction time compared to SBE.
Article
Medicine, General & Internal
Chul-Soo Lee, Seung-Beom Han, Ki-Mo Jang
Summary: Clinical outcomes after anterior cruciate ligament reconstruction have improved significantly, but residual rotational instability of the knee joint remains a major concern. Interest in the anterolateral ligament as a secondary stabilizer has led to attempts at combined reconstruction with the ACL, yet the ideal graft type and surgical technique have not been established.
MEDICINA-LITHUANIA
(2022)
Article
Orthopedics
Seung-Beom Han, Ki-Mo Jang, Jun-Hyun Kim, Sang-Bum Kim, Kyun-Ho Shin
Summary: The beneficial effects of residual varus (RV) alignment compared to mechanical alignment (MA) in total knee arthroplasty (TKA) for varus osteoarthritis are limited. Currently, TKA with neutral MA should be considered as the gold standard.
JOURNAL OF ORTHOPAEDIC SURGERY
(2022)
Review
Medicine, General & Internal
Jun-Gu Park, Seung-Beom Han, Chul-Soo Lee, Ok Hee Jeon, Ki-Mo Jang
Summary: This study reviewed the anatomy and biomechanics of anterolateral structures, surgical techniques, and the clinical outcomes of anterolateral procedures, including LET and ALLR, in patients with ACL deficiencies.
MEDICINA-LITHUANIA
(2022)
